Zobrazeno 1 - 10
of 45
pro vyhledávání: '"L. G. Humber"'
Autor:
L G Humber, Arvid Carlsson, Arne Svensson, Ekman A, A A Asselin, Håkan Wikström, Bengt Andersson, I Nilsson, Kjell A. Svensson, C Chidester
Publikováno v:
Journal of Medicinal Chemistry. 32:2273-2276
The enantiomers of 6,7,8,9-tetrahydro-N,N-dimethyl-3H-benz[e]indol-8- amine (1a) were prepared and tested for their actions on central dopamine and serotonin (5-HT) receptors. The dopaminergic effects were shown to reside in the (1)-R enantiomer. It
Publikováno v:
Canadian Journal of Chemistry. 54:2715-2722
The compound butaclamol hydrobromide crystallizes in space group P21/c with cell dimensions; a = 14.38(3), b = 13.31(3), c = 12.07(3) Å, β = 101.64(8)°. The structure was solved by Patterson methods and non-hydrogen atoms have been refined isotrop
Publikováno v:
Journal of Heterocyclic Chemistry. 13:311-316
The condensations of 1-(2-hydroxyphenyl) pyrroles with a variety of carbonyl compounds are shown to give new 4-substituted-4H-4-methylpyrrolo[2,1-c][1,4]benzoxazines. Some of the products were further functionalized. The ir, uv, and pmr spectra of th
Publikováno v:
Journal of Heterocyclic Chemistry. 12:937-940
The condensation of thiotryptophol with β-ketoesters and successive hydrolysis of the intermediates afforded the title compounds which represent a novel ring system. The reaction of thiotryptophol with ethyl propiolate in the presence of sodium meth
Publikováno v:
Canadian Journal of Chemistry. 58:1444-1448
(±)-Deoxybutaclamol, C25H31N, crystallizes in space group P21/a with cell dimensions: a = 16.626(3), b = 10.646(2), c = 11.278(3) Å, β = 90.47(4)°. The structure was solved by direct methods using the QTAN program. The coordinates were refined by
Autor:
L. G. Humber
Publikováno v:
Canadian Journal of Chemistry. 49:857-862
A simple six-step synthesis, from homoveratrylamine, of 5,6-dimethoxy-2,3,7,8,9,9a-hexahydro-1-(p-toluenesulfonyl)-1H-benzo[d,e-1,7]naphthyridine, the first representative of a novel heterocyclic ring system, is described. Various transformation prod
Publikováno v:
Journal of Medicinal Chemistry. 14:982-985
Publikováno v:
Journal of Heterocyclic Chemistry. 3:247-251
The syntheses of various oxidation states of the novel benzo[1, 2]cyclohepta[3, 4, 5-d, e]-isoquinoline ring system is described. The ring system was obtained by the Schmidt rearrangement, with exclusive alkyl migration, of 1, 6, 7, 11b-tetrahydro -
Publikováno v:
Canadian Journal of Chemistry. 42:2852-2861
Several routes to the synthesis of 1,4-disubstituted bicyclo[2.2.2]octanes have been explored and the syntheses of several such derivatives are reported. The 1,4-disubstituted bicyclo[2.2.2]-octane nucleus could not be prepared through an elimination
Autor:
W. I. Taylor, L. G. Humber
Publikováno v:
Canadian Journal of Chemistry. 33:1268-1270
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