Zobrazeno 1 - 10
of 47
pro vyhledávání: '"L. G. Babich"'
Autor:
L. G. Babich, S. G. Shlykov, O. A. Yesypenko, A. O. Bavelska-Somak, A. G. Zahoruiko, I. R. Horak, L. B. Drobot, S. O. Kosterin
Publikováno v:
The Ukrainian Biochemical Journal, Vol 94, Iss 2, Pp 24-30 (2022)
According to our earlier data, calix[4]arene chalcone amides modulate Ca ions exchange in the myometrium mitochondria and the level of inner membrane polarization that can potentially affect cell survival. To test this hypothesis, we studied the effe
Externí odkaz:
https://doaj.org/article/e4a3a92d825345df916fb24f66c87312
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 5-12 (2021)
Functional activity of mitochondria depends on ionized calcium content in its matrix. Thus, investigation of the ways to influence Ca2+ transport and accumulation in these organelles is an urgent issue. The aim of this work was to evaluate ionized ca
Externí odkaz:
https://doaj.org/article/90c0bf44f3454548b32081b162d8dab1
Autor:
S. G. Shlykov, A. M. Kushnarova-Vakal, A. V. Sylenko, L. G. Babich, О. Yu. Chunikhin, O. A. Yesypenko, V. I. Kalchenko, S. O. Kosterin
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 3, Pp 46-55 (2019)
Mitochondria are a key player in a wide range of the most important functions of the cell. Calixarenes are supramolecular compounds that have been widely used in bioorganic chemistry and biochemistry. The aim of this work was to study the effects of
Externí odkaz:
https://doaj.org/article/78860ea88ea14f45a9558e5cb2ed2fe7
Autor:
L. G. Babich, S. G. Shlykov, A. M. Kushnarova-Vakal, N. I. Kupynyak, V. V. Manko, V. P. Fomin, S. O. Kosterin
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 3, Pp 32-40 (2018)
The aim of the study was to show the relationships between ionized Ca concentration ([Ca2+]m) in the mitochondria matrix and functional activity of this organelle. [Ca2+]m was determined using the fluorescent probe Fluo-4, AM. Total level of Ca2+ acc
Externí odkaz:
https://doaj.org/article/8add5031a8ed482a86eef510a46eb27a
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 3, Pp 17-24 (2017)
It is known that Ca2+ accumulation in the mitochondria undergoes complex regulation by Ca2+ itself. But the mechanisms of such regulation are still discussed. In this paper we have shown that Ca ions directly or indirectly regulate the level of myome
Externí odkaz:
https://doaj.org/article/01c37ec5d516401ba6ab141e15166298
Publikováno v:
The Ukrainian Biochemical Journal, Vol 88, Iss 4, Pp 5-11 (2016)
Са2+-dependent regulation of Ca2+ exchange in mitochondria is carried out with participation of calmodulin. We have shown previously that calmodulin antagonists reduced the level of mitochondrial membrane polarization and induced increase of the io
Externí odkaz:
https://doaj.org/article/c8be84355b3d4e05836854e4fd8e88a5
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 5, Pp 54-60 (2015)
It is known that Са2+-dependent regulation of this cation exchange in mitochondria is carried out with participation of calmodulin. We had shown in a previous work using two experimental models: isolated mitochondria and intact myometrium cells, th
Externí odkaz:
https://doaj.org/article/0d52e2785f194909b324197aa4483750
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 6, Pp 18-30 (2014)
Review focuses on the analysis of literature data and own results concerning properties of mitochondria Са2+ transporting systems and their regulation. Three mechanisms for mitochondrial Ca2+ uptake are described: the electrogenic mitochondrial C
Externí odkaz:
https://doaj.org/article/be666391fdd844fea8b19c282fc26053
Publikováno v:
The Ukrainian Biochemical Journal, Vol 86, Iss 1, Pp 29-41 (2014)
Influence of calmodulin antagonists on mitochondrial membrane potential was investigated using a flow cytometry method, confocal microscopy and fluorescent potential-sensitive probes TMRM and MTG. Influence of different concentrations of calmodulin
Externí odkaz:
https://doaj.org/article/26721df6dff9476f9ee033214d39ce4e
Publikováno v:
Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 5-12 (2021)
Functional activity of mitochondria depends on ionized calcium content in its matrix. Thus, investigation of the ways to influence Ca2+ transport and accumulation in these organelles is an urgent issue. The aim of this work was to evaluate ionized ca