Zobrazeno 1 - 10 of 264 pro vyhledávání: '"L. Franken"'
1
Akademický článek
Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming
Autor: Dieke van Dinther, Henrike Veninga, Salvador Iborra, Ellen G.F. Borg, Leoni Hoogterp, Katarzyna Olesek, Marieke R. Beijer, Sjoerd T.T. Schetters, Hakan Kalay, Juan J. Garcia-Vallejo, Kees L. Franken, Lamin B. Cham, Karl S. Lang, Yvette van Kooyk, David Sancho, Paul R. Crocker, Joke M.M. den Haan
Publikováno v: Cell Reports, Vol 22, Iss 6, Pp 1484-1495 (2018)
Summary: Splenic CD169+ macrophages are located in the marginal zone to efficiently capture blood-borne pathogens. Here, we investigate the requirements for the induction of CD8+ T cell responses by antigens (Ags) bound by CD169+ macrophages. Upon Ag
Externí odkaz: https://doaj.org/article/84df6989ba8c45e3a1b26eff608999f9
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2
Akademický článek
Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome
Autor: Fergal J. Duffy, January Weiner, Scott Hansen, David L. Tabb, Sara Suliman, Ethan Thompson, Jeroen Maertzdorf, Smitha Shankar, Gerard Tromp, Shreemanta Parida, Drew Dover, Michael K. Axthelm, Jayne S. Sutherland, Hazel M. Dockrell, Tom H. M. Ottenhoff, Thomas J. Scriba, Louis J. Picker, Gerhard Walzl, Stefan H. E. Kaufmann, Daniel E. Zak, The GC6-74 Consortium, S. H. E. Kaufmann, S. K. Parida, R. Golinski, J. Maertzdorf, J. Weiner, M. Jacobson, G. McEwen, G. Walzl, G. F. Black, G. van der Spuy, K. Stanley, M. Kriel, N. Du Plessis, N. Nene, A. G. Loxton, N. N. Chegou, S. Suliman, T. Scriba, M. Fisher, H. Mahomed, J. Hughes, K. Downing, A. Penn-Nicholson, H. Mulenga, B. Abel, M. Bowmaker, B. Kagina, W. Kwong, C. W. Hanekom, T. H. M. Ottenhoff, M. R. Klein, M. C. Haks, K. L. Franken, A. Geluk, K. E. van Meijgaarden, S. A. Joosten, D. van Baarle, F. Miedema, W. H. Boom, B. Thiel, J. Sadoff, D. Sizemore, S. Ramachandran, L. Barker, M. Brennan, F. Weichold, S. Muller, L. Geiter, G. Schoolnik, G. Dolganov, T. Van, H. Mayanja-Kizza, M. Joloba, S. Zalwango, M. Nsereko, B. Okwera, H. Kisingo, H. M. Dockrell, S. Smith, P. Gorak-Stolinska, Y.-G. Hur, M. Lalor, J.-S. Lee, A. C. Crampin, N. French, B. Ngwira, A. B. Smith, K. Watkins, L. Ambrose, F. Simukonda, H. Mvula, F. Chilongo, J. Saul, K. Branson, D. Kassa, A. Abebe, T. Mesele, B. Tegbaru, R. Howe, A. Mihret, A. Aseffa, Y. Bekele, R. Iwnetu, M. Tafesse, L. Yamuah, M. Ota, J. Sutherland, P. Hill, R. Adegbola, T. Corrah, M. Antonio, T. Togun, I. Adetifa, S. Donkor, P. Andersen, I. Rosenkrands, M. Doherty, K. Weldingh
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB index cases (HHCs) and a string
Externí odkaz: https://doaj.org/article/1eba36dc045c44aa95b786e37918a63e
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3
Akademický článek
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4
Akademický článek
Pulmonary lymphangiomatosis: insights into an ultra-rare disease
Autor: M. Polke, N. Polke, S. Piel, E. Brunnemer, J. Wälscher, K. Buschulte, A. Warth, C. P. Heussel, M. Eichinger, L. Frankenstein, M. Eichhorn, S. Miliauskas, F. J. F. Herth, M. Kreuter
Publikováno v: Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Pulmonary lymphangiomatosis (PL) is an ultrarare disease characterized by diffuse infiltration of the lung, pleura and/or mediastinum by abnormal lymphatic proliferation. Consented diagnostic or treatment approaches are not establ
Externí odkaz: https://doaj.org/article/7e98172422a1443db1fec9552c75a7d6
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5
Akademický článek
A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts
Autor: Fergal J. Duffy, Ethan Thompson, Katrina Downing, Sara Suliman, Harriet Mayanja-Kizza, W. Henry Boom, Bonnie Thiel, January Weiner III, Stefan H. E. Kaufmann, Drew Dover, David L. Tabb, Hazel M. Dockrell, Tom H. M. Ottenhoff, Gerard Tromp, Thomas J. Scriba, Daniel E. Zak, Gerhard Walzl, the GC6-74 Consortium, S. H. E. Kaufmann, S. K. Parida, R. Golinski, J. Maertzdorf, J. Weiner, M. Jacobson, G. McEwen, G. Walzl, G. Black, G. van der Spuy, K. Stanley, M. Kriel, N. Du Plessis, N. Nene, A. Loxton, N. N. Chegou, S. Suliman, T. Scriba, H. Mahomed, M. Erasmus, O. Xasa, A. Veldsman, J. Hughes, K. Downing, A. Penn-Nicholson, H. Mulenga, B. Abel, M. Bowmaker, B. Kagina, W. Kwong C, W. Hanekom, T. H. M. Ottenhoff, M. R. Klein, M. C. Haks, K. L. Franken, A. Geluk, K. E. van Meijgaarden, S. A. Joosten, D. van Baarle, F. Miedema, W. H. Boom, B. Thiel, J. Sadoff, D. Sizemore, S. Ramachandran, L. Barker, M. Brennan, F. Weichold, S. Muller, L. Geiter, G. Schoolnik, G. Dolganov, T. Van, H. Mayanja-Kizza, M. Joloba, S. Zalwango, M. Nsereko, B. Okwera, H. Kisingo, H. Dockrell, S. Smith, P. Gorak-Stolinska, Y.-G. Hur, M. Lalor, J.-S. Lee, A. C. Crampin, N. French, B. Ngwira, A. B. Smith, K. Watkins, L. Ambrose, F. Simukonda, H. Mvula, F. Chilongo, J. Saul, K. Branson, D. Kassa, A. Abebe, T. Mesele, B. Tegbaru, R. Howe, A. Mihret, A. Aseffa, Y. Bekele, R. Iwnetu, M. Tafesse, L. Yamuah, M. Ota, J. Sutherland, P. Hill, R. Adegbola, T. Corrah, M. Antonio, T. Togun, I. Adetifa, S. Donkor, P. Andersen, I. Rosenkrands, M. Doherty, K. Weldingh
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Biomarkers that predict who among recently Mycobacterium tuberculosis (MTB)-exposed individuals will progress to active tuberculosis are urgently needed. Intracellular microRNAs (miRNAs) regulate the host response to MTB and circulating miRNAs (c-miR
Externí odkaz: https://doaj.org/article/a450c97d56b9481c89cbc4507d35a4ef
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6
Akademický článek
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7
Akademický článek
Uptake of HLA Alloantigens via CD89 and CD206 Does Not Enhance Antigen Presentation by Indirect Allorecognition
Autor: Eytan Breman, Jurjen M. Ruben, Kees L. Franken, Mirjam H. M. Heemskerk, Dave L. Roelen, Frans H. Claas, Cees van Kooten
Publikováno v: Journal of Immunology Research, Vol 2016 (2016)
In organ transplantation, alloantigens are taken up by antigen presenting cells and presented via the indirect pathway to T-cells which in turn can induce allograft rejection. Monitoring of these T-cells is of major importance; however no reliable as
Externí odkaz: https://doaj.org/article/7d51bfd1bb4d4304ab38afd41f3d8a15
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8
Akademický článek
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9
Akademický článek
Host cytokine responses induced after overnight stimulation with novel M. tuberculosis infection phase-dependent antigens show promise as diagnostic candidates for TB disease.
Autor: Paulin N Essone, Novel N Chegou, Andre G Loxton, Kim Stanley, Magdalena Kriel, Gian van der Spuy, Kees L Franken, Tom H Ottenhoff, Gerhard Walzl
Publikováno v: PLoS ONE, Vol 9, Iss 7, p e102584 (2014)
BACKGROUND: We previously identified Mycobacterium tuberculosis (M.tb) antigen-induced host markers that showed promise as TB diagnostic candidates in 7-day whole blood culture supernatants. The aim of the present study was to evaluate the utility of
Externí odkaz: https://doaj.org/article/458f59a62f4c443da9d238626a1ee5e3
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