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Akademický článek

Neocortical cholinergic pathology after neonatal brain injury is increased by Alzheimer's disease-related genes in mice

Autor: Leslie Doucette, Victoria Turnbill, Katherine Carlin, Andrew Cavanagh, Benjamin Sollinger, Nazli Kuter, Debra L. Flock, Shenandoah Robinson, Raul Chavez-Valdez, Lauren Jantzie, Lee J. Martin, Frances J. Northington

Publikováno v: Neurobiology of Disease, Vol 200, Iss , Pp 106629- (2024)

Hypoxic-ischemic encephalopathy (HIE) in neonates causes mortality and neurologic morbidity, including poor cognition with a complex neuropathology. Injury to the cholinergic basal forebrain and its rich innervation of cerebral cortex may also drive

Externí odkaz: https://doaj.org/article/035c2c747a734edb8ecad5c525f26ffc

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Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia‐ischemia

Autor: Debra L. Flock, Raul Chavez-Valdez, Frances J. Northington, Victoria Turnbill, Lee J. Martin, Daniella Asafu‐Adjaye, Panagiotis Kratimenos

Publikováno v: J Comp Neurol

Neonatal hypoxic-ischemic encephalopathy (HIE) causes lifelong neurologic disability. Despite the use of therapeutic hypothermia, memory deficits and executive functions remain severely affected. Cholinergic neurotransmission from the basal forebrain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4047ad052eaa5b0d21701af17e866a8b
https://doi.org/10.1002/cne.25263

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Cover Image, Volume 530, Issue 8

Autor: Frances J. Northington, Panagiotis Kratimenos, Victoria Turnbill, Debra L. Flock, Daniella Asafu‐Adjaye, Raul Chavez‐Valdez, Lee J. Martin

Publikováno v: Journal of Comparative Neurology. 530

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b6a1e4ae94c8fc633cdfbcc128d1631
https://doi.org/10.1002/cne.25327

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Author response for 'Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia‐ischemia'

Autor: null Frances J. Northington, null Panagiotis Kratimenos, null Victoria Turnbill, null Debra L. Flock, null Daniella Asafu‐Adjaye, null Raul Chavez‐Valdez, null Lee J. Martin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f9db234adff8b16d54376542e5228fe
https://doi.org/10.1002/cne.25263/v3/response1

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Author response for 'Basal forebrain magnocellular cholinergic systems are damaged in mice following neonatal hypoxia‐ischemia'

Autor: Raul Chavez-Valdez, Panagiotis Kratimenos, Lee J. Martin, Debra L. Flock, Daniella Asafu‐Adjaye, Victoria Turnbill, Frances J. Northington

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1fec8807de94d52ca72c5c90a142159d
https://doi.org/10.1002/cne.25263/v2/response1

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Akademický článek

Neonatal mice lacking functional Fas death receptors are resistant to hypoxic–ischemic brain injury

Autor: Ernest M. Graham, R.Ann Sheldon, Debra L. Flock, Donna M. Ferriero, Lee J. Martin, Declan P. O'Riordan, Frances J. Northington

Publikováno v: Neurobiology of Disease, Vol 17, Iss 1, Pp 89-98 (2004)

Neonatal hypoxia–ischemia (HI) upregulates Fas death receptor expression in the brain, and alterations in expression and activity of Fas signaling intermediates occur in neonatal brain injury. B6.MRL-Tnfrsf6lpr mice lacking functional Fas death rec

Externí odkaz: https://doaj.org/article/c0761381b0ae432b853620a4137bd7c0

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An Inhibitor of the Mitochondrial Permeability Transition Pore Lacks Therapeutic Efficacy Following Neonatal Hypoxia Ischemia in Mice

Autor: Oliver Avaritt, Courtney L. Robertson, Debbie L. Flock, Lee J. Martin, Manda Saraswati, Frances J. Northington, Jing Fang, Raul Chavez-Valdez

Publikováno v: Neuroscience. 406:202-211

Neonatal hypoxic ischemic (HI) brain injury causes lifelong neurologic disability. Therapeutic hypothermia (TH) is the only approved therapy that partially mitigates mortality and morbidity. Therapies specifically targeting HI-induced brain cell deat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa5fcfcc821f289fbabaf2b470a0ba65
https://doi.org/10.1016/j.neuroscience.2019.02.030

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Calbindin-1 Expression in the Hippocampus following Neonatal Hypoxia-Ischemia and Therapeutic Hypothermia and Deficits in Spatial Memory

Autor: Dafne Sanabria, Raul Chavez-Valdez, Janasha Goffigan-Holmes, Debra L. Flock, Johana Diaz

Publikováno v: Dev Neurosci

Hippocampal injury following neonatal hypoxia-ischemia (HI) leads to memory impairments despite therapeutic hypothermia (TH). In the hippocampus, the expression of calbindin-1 (Calb1), a Ca2+-buffering protein, increases during postnatal development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69abcea61ea05ced9d32cef55b705d52
https://doi.org/10.1159/000497056

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Seizure Susceptibility Correlates with Brain Injury in Male Mice Treated with Hypothermia after Neonatal Hypoxia-Ischemia

Autor: Debra L. Flock, Melanie A. McNally, Raul Chavez-Valdez, Carl E. Stafstrom, Ryan J. Felling, Frances J. Northington

Publikováno v: Dev Neurosci

Hypoxic-ischemic encephalopathy is a common neonatal brain injury associated with significant morbidity and mortality despite the administration of therapeutic hypothermia (TH). Neonatal seizures and subsequent chronic epilepsy are frequent in this p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ab4e3e0caeadae2faba885747f6ddf
https://doi.org/10.1159/000496468

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Akademický článek

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