Výsledky vyhledávání - "L. F. de Leij"

Susceptibility to development of Mycobacterium ulcerans disease: review of possible risk factors

Autor: Y. Stienstra, W. T. A. van der Graaf, G. J. te Meerman, T. H. The, L. F. de Leij, T. S. van der Werf

Publikováno v: Tropical Medicine & International Health, 6(7), 554-562. Wiley

Mycobacterium ulcerans disease, also known as Buruli ulcer (BU), is a disease of subcutaneous fat tissue. BU is prevalent in riverine and swamp areas of the tropical zone in Africa, Asia and South America, and a few scattered foci in Australia. The m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d73594f61897dd954574f1c3c3c5dd3
https://pubmed.ncbi.nlm.nih.gov/11469950

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The epithelial glycoprotein 2 (EGP-2) promoter-driven epithelial-specific expression of EGP-2 in transgenic mice: a new model to study carcinoma-directed immunotherapy

Autor: P M, McLaughlin, M C, Harmsen, W H, Dokter, B J, Kroesen, H, van der Molen, M G, Brinker, H, Hollema, M H, Ruiters, C H, Buys, L F, de Leij

Publikováno v: Cancer research. 61(10)

The human pancarcinoma-associated epithelial glycoprotein-2 (EGP-2), a M(r) 38,000 transmembrane antigen also known as 17-1A or Ep-CAM, is commonly used for targeted immunotherapy of carcinomas because it is strongly expressed by most carcinomas. EGP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc47d7c873ea72167757f5e5573f1636
https://pubmed.ncbi.nlm.nih.gov/11358833

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Rapid decreases in donor-specific cytotoxic T lymphocyte precursor frequencies and graft outcome after liver and lung transplantation

Autor: A, de Haan, A P, van den Berg, W, van der Bij, B G, Hepkema, E, Bruin-van Dijk, I, van der Gun, S P, Lems, M J, Slooff, E B, Haagsma, L F, de Leij, J, Prop

Publikováno v: Transplantation. 71(6)

A decrease in donor-specific T cell precursor frequencies as seen late, one or more years, after transplantation is assumed to reflect transplantation tolerance, a condition important for long term acceptance of the allograft. However, such late decr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d2a76326095d00c4961c1b2a9133eb11
https://pubmed.ncbi.nlm.nih.gov/11330529

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Pharmacokinetics and whole body distribution of elastase derived angiostatin (K1-3) in rats

Autor: G, Molema, I, van Veen-Hof, A M, van Loenen-Weemaes, J H, Proost, L F, de Leij, D K, Meijer

Publikováno v: International journal of cancer. 91(1)

In the current study, we determined short-term pharmacokinetics and whole body distribution of elastase derived angiostatin [angiostatin(k1-3)] in rats after i.v. injection of radiolabelled protein. Since in gamma-camera studies, no tumor specific an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::900e74fa88867ff6d92bd8c3da233d27
https://pubmed.ncbi.nlm.nih.gov/11149408

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Enzyme and cytokine effects on the impaired onset of the murine foreign-body reaction to dermal sheep collagen

Autor: I M, Khouw, P B, van Wachem, J A, Plantinga, L F, de Leij, M J, van Luyn

Publikováno v: Journal of biomedical materials research. 54(2)

Subcutaneous implantation of biodegradable hexamethylenediisocyanate crosslinked dermal sheep collagen (HDSC) elicited little foreign-body reaction in mice in contrast to rats. If the factor(s) resulting in this minor foreign-body reaction are better

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54516c98708b02cde911923174865557
https://pubmed.ncbi.nlm.nih.gov/11093183

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The foreign body reaction to a biodegradable biomaterial differs between rats and mice

Autor: I M, Khouw, P B, van Wachem, G, Molema, J A, Plantinga, L F, de Leij, M J, van Luyn

Publikováno v: Journal of biomedical materials research. 52(3)

Before a biomaterial can be applied in the clinic, biocompatibility must be tested in in vivo models, by monitoring the foreign body reaction. In this study, we compared the foreign body reaction (FBR) to the biodegradable biomaterial hexamethylenedi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5076371af0aa98c0d7e980c29ee44422
https://pubmed.ncbi.nlm.nih.gov/11007611

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Purging of epithelial tumor cells from peripheral blood stem cells by means of the bispecific antibody BIS-1

Autor: C P, Schröder, B J, Kroesen, L F, de Leij, E G, de Vries

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)

Peripheral blood stem cell (PBSC) support in breast cancer patients allows high-dose chemotherapy, but tumor cell contamination of the PBSCs is a potential source of relapse. Specific carcinoma cell killing can be obtained by retargeting activated T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce07094396d254a08ffafe0914ef858f
https://pubmed.ncbi.nlm.nih.gov/10873108

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Activation of alloreactive T cells by allogeneic nonprofessional antigen-presenting cells and interleukin-12 from bystander autologous professional antigen-presenting cells

Autor: A, de Haan, I, van der Gun, E, van Dijk, B G, Hepkema, J, Prop, L F, de Leij

Publikováno v: Transplantation. 69(8)

After solid organ transplantation most alloantigens are presented to the recipient's immune system by normal tissue cells, which can be considered to act as nonprofessional antigen-presenting cells (APC). It is well accepted that such nonprofessional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02680b8433ed4d93a0a7ebc618c360d8
https://pubmed.ncbi.nlm.nih.gov/10836375

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Decreased donor-specific cytotoxic T cell precursor frequencies one year after clinical lung transplantation do not reflect transplantation tolerance: a comparison of lung transplant recipients with or without bronchiolitis obliterans syndrome

Autor: A, de Haan, I, van der Gun, B G, Hepkema, W J, de Boer, W, van der Bij, L F, de Leij, J, Prop

Publikováno v: Transplantation. 69(7)

Decreased in vitro T cell alloreactivity, demonstrated by decreased frequencies of peripheral blood donor-specific T cell precursors, may reflect a tolerant state after transplantation and lower the risk for development of chronic graft dysfunction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::692bdfe99c5b1138a7334f713ce300bc
https://pubmed.ncbi.nlm.nih.gov/10798767

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The ubiquitin-activating enzyme E1-like protein in lung cancer cell lines

Autor: P M, McLaughlin, W, Helfrich, K, Kok, M, Mulder, S W, Hu, M G, Brinker, M H, Ruiters, L F, de Leij, C H, Buys

Publikováno v: International journal of cancer. 85(6)

The UBE1L gene isolated from the chromosome 3p21 region has an extremely reduced level of mRNA in lung cancer. Sequence analysis showed a 45% homology to the human ubiquitin-activating enzyme E1 at the amino acid level. To further characterize the pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::170d86e94f74727fe2fd8d564c42697d
https://pubmed.ncbi.nlm.nih.gov/10709110

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