Zobrazeno 1 - 7
of 7
pro vyhledávání: '"L. F. Gumarova"'
Autor:
I. V. Galyametdinova, A. A. Parfenov, Vladimir V. Zobov, V. E. Semenov, Nail Nazarov, L. R. Khasanshina, D. A. Kondrashina, A. B. Vyshtakalyuk, L. F. Gumarova, G. P. Belyaev
Publikováno v:
Russian Chemical Bulletin. 68:2307-2315
A salt-like conjugate of xymedone with para-aminobenzoic acid in a series of pyrimidine derivatives was synthesized, and its hepatoprotective properties were studied. The compound studied exhibits a cytoprotective effect at a concentration of 25 μmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7874bd7817fce605075a0c783f8c244
https://doi.org/10.1007/s11172-019-2704-z
https://doi.org/10.1007/s11172-019-2704-z
Autor:
Darya A Kondrashina, I. V. Galyametdinova, Grigory P Belyaev, A. B. Vyshtakalyuk, Vyacheslav E. Semenov, Vladimir V. Zobov, A. A. Parfenov, Leyla R Khasanshina, L. F. Gumarova, Nail Nazarov
Publikováno v:
Journal of biochemical and molecular toxicologyREFERENCES. 35(3)
The aim of the study was to investigate the hepatoprotective properties of the conjugate of the xymedon drug substance with succinic acid (1a). The study presents an in vitro comparative evaluation of the cytotoxicity and cytoprotective properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::680ceff37bf8dc15b5bbb4ee4dba81b1
https://pubmed.ncbi.nlm.nih.gov/33156957
https://pubmed.ncbi.nlm.nih.gov/33156957
Autor:
A. D. Latipova, Vladimir V. Zobov, L. F. Gumarova, A. B. Vyshtakalyuk, A. A. Parfenov, M. A. Sysoeva, E. V. Sysoeva
Publikováno v:
BioNanoScience. 9:528-538
The purpose of this study is to identify hepatoprotective properties of melanins from aqueous extracts of Inonotus obliquus distinguished by microwave modes used in extraction in both in vitro and in vivo studies. In vitro tests were used in studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeed85f070fe5d7f7e84bfb641f4b652
https://doi.org/10.1007/s12668-019-0595-y
https://doi.org/10.1007/s12668-019-0595-y
Autor:
Vyacheslav E. Semenov, Georgii Valentinovich Cherepnev, A. B. Vyshtakalyuk, Vladimir V. Zobov, L. F. Gumarova, I. V. Galyametdinova, A. A. Parfenov, N. G. Nazarov
Publikováno v:
BioNanoScience. 8:845-858
The main purpose of the work is to study pharmacological peculiar properties of effect of pyrimidine derivatives, salt-like conjugates of the pyrimidine-based drug Xymedon (I) with biogenic acids (succinic (II), l-ascorbic (III), para-aminobenzoic (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c67829c0ecda05b319d44a4b83f52ea5
https://doi.org/10.1007/s12668-018-0526-3
https://doi.org/10.1007/s12668-018-0526-3
Autor:
I. V. Galyametdinova, K. N. Bushmeleva, I. A. Sudakov, L. F. Gumarova, A. A. Parfenov, A. B. Vyshtakalyuk, Nail Nazarov, V. E. Semenov, Vladimir V. Zobov
Publikováno v:
Russian Chemical Bulletin. 67:705-711
Antiradical activity and antioxidant properties of a conjugate of Xymedon with l-ascorbic acid were studied. In contrast to Xymedon, a conjugate of Xymedon with l-ascorbic acid was found to react with free radicals. Pro-oxidant activity of the conjug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b852d16b3924129a19ea72bc1a8aa4a
https://doi.org/10.1007/s11172-018-2126-3
https://doi.org/10.1007/s11172-018-2126-3
Autor:
A. B. Vyshtakalyuk, I. V. Galyametdinova, A. A. Parfenov, Vladimir V. Zobov, Vyacheslav Semenov, L. F. Gumarova, Nail Nazarov
Publikováno v:
BioNanoScience. 7:616-622
The main objective of this work was a comparative evaluation of hepatoprotective activity of pyrimidine derivative of the active compound of Xymedon (1-(s-oxyethyl)-4.6-dimethyl-1.2-dihydro-2-oxopirimidon) and its derivatives with methionine and asco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2493cd2ddd6899938a2e972cb5058ec
https://doi.org/10.1007/s12668-017-0461-8
https://doi.org/10.1007/s12668-017-0461-8
Autor:
I. V. Galyametdinova, A. A. Parfenov, A. B. Vyshtakalyuk, Svetlana A. Kondrashova, Nail Nazarov, M. S. Shashyn, Oksana A. Lenina, V. E. Semenov, V. S. Reznic, Vladimir V. Zobov, Sh. K. Latypov, G. V. Cherepnev, L. F. Gumarova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 43:604-611
Based on the active ingredient of the drug Ximedon (1,2-dihydro-4,6-dimethyl-1-N-(2-hydroxyethyl)pyrimidone-2, referred below to as pyrimidine (I), novel derivatives containing biogenic acids: succinic, L-ascorbic, para-aminobenzoic, nicotinic, and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348c107d2b1772efe5411547eb9f841f
https://doi.org/10.1134/s106816201704015x
https://doi.org/10.1134/s106816201704015x