Zobrazeno 1 - 10 of 71 pro vyhledávání: '"L. F. Martins"'
1
Akademický článek
Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites
Autor: Margarida L. F. Martins, Paniz Heydari, Wenlong Li, Alejandra Martínez-Chávez, Nikkie Venekamp, Maria C. Lebre, Luc Lucas, Jos H. Beijnen, Alfred H. Schinkel
Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)
The psychedelic alkaloid ibogaine is increasingly used as an oral treatment for substance use disorders, despite being unlicensed in most countries and having reported adverse events. Using wild-type and genetically modified mice, we investigated the
Externí odkaz: https://doaj.org/article/42ec522121d9424fb99e7f0e402b71a9
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3
Akademický článek
The Neuroprotective Action of Amidated-Kyotorphin on Amyloid β Peptide-Induced Alzheimer’s Disease Pathophysiology
Autor: Rita F. Belo, Margarida L. F. Martins, Liana Shvachiy, Tiago Costa-Coelho, Carolina de Almeida-Borlido, João Fonseca-Gomes, Vera Neves, Hugo Vicente Miranda, Tiago F. Outeiro, Joana E. Coelho, Sara Xapelli, Cláudia A. Valente, Montserrat Heras, Eduard Bardaji, Miguel A. R. B. Castanho, Maria José Diógenes, Ana M. Sebastião
Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
Kyotorphin (KTP, l-tyrosyl-l-arginine) is an endogenous dipeptide initially described to have analgesic properties. Recently, KTP was suggested to be an endogenous neuroprotective agent, namely for Alzheimer’s disease (AD). In fact, KTP levels were
Externí odkaz: https://doaj.org/article/23add04407fb425ba6cdc74be1ceea14
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5
P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib
Autor: Nancy H.C. Loos, Hilde Rosing, Margarida L. F. Martins, Maria C. Lebre, Danielle de Jong, Alfred H. Schinkel, Jos H. Beijnen, Matthijs M. Tibben, Sümeyra Mucuk
Publikováno v: Molecular pharmaceutics. 18(12)
Niraparib (Zejula), a selective oral PARP1/2 inhibitor registered for ovarian, fallopian tube, and primary peritoneal cancer treatment, is under investigation for other malignancies, including brain tumors. We explored the impact of the ABCB1 and ABC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c061d7a3983347bd5f4f1d4ccf059ff2
https://pubmed.ncbi.nlm.nih.gov/34730366
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6
The suitability of oral diacetylmorphine in treatment-refractory patients with heroin dependence: A scoping review
Autor: Wim van den Brink, Margarida L. F. Martins, Thilo Beck, Erica A. Wilthagen, Ambros Uchtenhagen, Nelda de Grave, Alfred H. Schinkel, Jos H. Beijnen, Eugenia Oviedo-Joekes
Publikováno v: Drug and alcohol dependence. 227
Objective To review the scientific literature on the pharmacokinetics, pharmacodynamics and clinical efficacy and safety of (supervised) oral diacetylmorphine for patients with severe heroin dependence. Methods The PubMed, Embase, Web of Science and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebacc0f563cc4d6a7a8ed4ddc347b26c
https://pubmed.ncbi.nlm.nih.gov/34482044
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8
Teoria e Prática Multidisciplinar em Saúde - Volume 1
Autor: Thadeu R de ARAÚJO, Pollyana R de ARAÚJO, Simone P FERREIRA, Vilk J S BARROS, Eudilene R SILVEIRA, Errus J C VIANA, Rebeca L MONTEIRO, Thaís R NOGUEIRA, Claudiane B de SOUSA, Andrea F L SANTOS, Naelson R de S GOMES, Luanna S de M EVANGELISTA, Stephanie O SILVA, Vitoria LC LIMA, José M de A COSTA, Kelly S COSTA, Milenia F COSTA, Tailana SA LEITE, Diellison L dos S LIMA, Luís FP CUBILLOS, Angela dos S SILVA, Wellington M LEITE, Ingrid RL VIEIRA, João GR dos SANTOS, Márcia A FERNANDES, Sandra C PILLON, Isabel Teresa F C BRANCO, Leilanir de Sousa CARVALHO, Gabriela G de S LIMA, Esther de S FERREIRA, Lauana O CARNEIRO, Andréia G de SOUSA, Magda M de Sousa LIMA, Francisco J M BRANDÃO, Dariane V de ARAÚJO, Joselany Á CAETANO, Lívia M BARROS, Adriana R NASCIMENTO, Nicolle A F BARROSO, Mônica A G LIMA, Yara A GUIMARÃES, Gabriela S RODRIGUES, Maria L X FEIJÃO, Antônia T B CASTRO, Yandra K B BRAGA, Francisca N S DUARTE, Luciene S PONTES, Francisca N da Silva SABINO, Alana F RIOS, Antonio L F MARTINS, Tiago S FARIAS, Andréa C A MOREIRA, Alexia L COSTA, Paloma AF LIMA, Pallysson P SILVA, Beatriz GS OLIVEIRA, Ana AA COSTA, Débora M CAVALHEIRO, Lairton B OLIVEIRA, Stéfany RS MELO, Antonio B do N RODRIGUES, Lucas R UCHÔA, Thalia M De S SOARES, Anaalyce P G OLIVEIRA, Kayra C GUIMARÃES, Caio A de OLIVEIRA, Antonio C M BARROS, Caroline R de ALMEIDA, Lucas ANANIAS, Maria Andréia A BORGES, Helen C V PIRES, Renato A LOPES, Marineide R Do AMORIM, André S ROCHA, Ana A PEREIRA, Maria A C MELO, Janaína C de SOUSA, Kyaya G de CARVALHO, Camilla A L VIEIRA, Paulo H D QUINDERÉ, Artur B GOMES, Érica C TEIXEIRA, Irma B F CALOU, Jardel A COSTA, Ana J R S CASTRO, Aldaisa P LOPES, Fernanda KC MACEDO, Gabrielly C NASCIMENTO, Vanessa M M ROCHA, Wanessa S MACEDO, Ticiana M L AMORIM, Aurélio V G BARBOSA, Mayara A F, Tamares D BANDEIRA, Janaina K de OLIVEIRA, Tália C de LIMA, Emanuella S da SILVA, Maria A G BARBOSA, Benedita N S PEREIRA, Francisco M S M JÚNIOR, José R P LIMA, Francisco F M RUFINO, Ana Mara F MELO, Carlos A F de OLIVEIRA, Bruno V P COSTA, Keyla M G M COELHO, Sara de L SAMPAIO, Cristiano A F LAGES, Samilly G de OLIVEIRA, Francisca D de P BRAGA, Maria H A LEITÃO, Suelane C S de LIMA, Danieles G OLIVEIRA, Adrielly C OLIVEIRA, Deidiane M ALVES, Deysilane dos S GONÇALVES, Antônio RG SIMPLÍCIO, Bruno A FROTA, Luiz G da S NETO, Elisangela P OLIVEIRA, Izonete P da S MELO, Katiane V da SILVA, Layza K de J SILVA, Iasmin E dos S SILVA, Emanuelle S FERREIRA, Lyandra D SILVA, Marcelo N RÊGO, Marcos P C CASTRO, Nilmara C SILVA, Camila GB ARAÚJO, Eveny S MELO, Karina S RODRIGUES, Cristiane E LIMA, Isabel CP LIMA, Gabriella PACHECO, Marília S SOUSA, Artur S COSTA, Maria PS NASCIMENTO, Rafael GA BACELAR, José H S FILHO, Gilmara F DIAS, Juliana A IANICELI, João F S JÚNIOR, Victor LF TÔRRES, Eldo JR SANTOS, Maria M GP NÓBREGA, Maria CS MURATORI, Helder ML JÚNIOR, Vitória S BRAGA, Heloisa R M LIMA, Edvaldo P de MOURA FILHO, Rodrigo S SILVA, João A de Moraes CASTRO, Vinicius O C NOGUEIRA, Herika da S SOUZA, Karynne M de SAMPAIO, Mayane C A PEREIRA, Isabela S UCHÔA, Francisco APS FREITAS, Matheus F de CASTRO, Suzanne TT NASCIMENTO, Maria do AV MAGALHÃES, Jackson BG DANTAS, Larissa MF GONÇALVES, Julia MV DADA, Vanessa CASTRO, Fernando M De CARVALHO, Tuanny CM DAMASCENO, Marlos E De S COSTA, Felicianna CF MACHADO, Antônio ANM JÚNIOR, Manoel L Da SILVA FILHO, Jackson L F CARVALHO, Bárbara EN SILVA, Ana Lívia CB OLIVEIRA, Jardel Nascimento da CRUZ, Andreia Rodrigues de Moura da Costa VALLE, Jéssica AM de OLIVEIRA, Nathássia M de MEDEIROS, Gislene Cristiene M TÔRRES, Jhonata de C RIBEIRO, Eduardo B A de LIMA, Simone R ROCHA, Francisco E da S JÚNIOR, Mara J M COSTA, Kaliny V dos Santos A PEREIRA, Andressa L de Sousa SANTANA, Antônia S de Jesus SOUSA, Diego F B ARAGÃO, Ediney R LEAL, Estevão E L DINIZ, Francisco E de Sousa BORGES, Fabiana N D OSTERNES, Hisla S do NASCIMENTO, John L L VIEIRA, Márdila C F e CARVALHO, Maria H C SARAIVA, Nerley P MESQUITA, Paula V de Sousa VERA, Rita de Cássia D MOURA, Robson W V de MOURA, Sayure G A da SILVA, Werbethe A N da SILVA, Kellícia R ARRAIS, Kamilla R ARRAIS, Andréa P da SILVA, Julyanne dos S NOLÊTO, Hernandes F C OLIVEIRA, Klicia G N MENESES, Aline R OLIVEIRA, Dinaura M CRUZ, Lara R LIRA, Conceição N D de SOUSA, Jefferson T NUNES, Larissa R LIRA, Ana K S de OLIVEIRA, Lianna P CUNHA, Elivone C da SILVA, Graciana R O PAZ, Deusineide da C MORAES, Maria de L F de Sousa ALENCAR, Patricia de S SANTOS, Jancielle S SANTOS, Lílian M V de MORAES, Suelen C R da ROCHA, Bárbara E do N SILVA, Michele R de OLIVEIRA, Izaiane P R de SOUSA, Hiêza M ARAÚJO, Débora V L C GUIMARÃES, Maria A A PEREIRA, Jessianny P C RODRIGUES, Alana M FONTENELE, Shuziany C G de LIMA, Aline P de AGUIAR, Erica R XIMENES, Pedro H G AMARAL, Débora S de OLIVEIRA, Kimberly M M FONTENELE, Rebeca F da SILVA, Antônia E A LIMA, Leyde V B da SILVA, Matheus S SOTERO, Mateus VIG NASCIMENTO, Amanda A FERREIRA, Yula PSF de MENESES, Ingride S LINHARES, Luana S PINHEIRO, Moisés M da SILVA, Amanda A M de CARVALHO, Nithelly O CABRAL, Natalia de S CABRAL, Maria A F da SILVA, Iasmim M LIMA, Josiane da S OLIVEIRA, Maria Francisca de S O CABRAL, Ana R N LIMA, Mônica N de LIMA, Rayane M BRITO, Maria J da SILVA, Francisca T P de SOUZA, Francisca C de SOUSA, Laime A M de ARAÚJO, Danielle P da SILVA, Larissa da S LANDIM, Márcio A de ALMEIDA, Murilo R P JUNIOR, Valéria G de LUCENA, Tainá A ROCHA, Paula H de F CAROLINO, Nara M P LEAL, Francisco O da S MARTINS, Maria A de S RAMOS, Francisca E de Sousa BORGES
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::751d512fa30ccbd25f2ad78d350b8e5f
https://doi.org/10.29327/513530
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9
Akademický článek
Genetic and morphometric divergence of an invasive bird: the introduced house sparrow (Passer domesticus) in Brazil.
Autor: Marcos R Lima, Regina H F Macedo, Thaís L F Martins, Aaron W Schrey, Lynn B Martin, Staffan Bensch
Publikováno v: PLoS ONE, Vol 7, Iss 12, p e53332 (2012)
Introduced species are interesting systems for the study of contemporary evolution in new environments because of their spatial and temporal scales. For this study we had three aims: (i) to determine how genetic diversity and genetic differentiation
Externí odkaz: https://doaj.org/article/de8bcab2351d46e194bf18ac0b4be333
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