Zobrazeno 1 - 10
of 456
pro vyhledávání: '"L. Eales"'
Autor:
Kate E.R. Hollinshead, Haydn Munford, Katherine L. Eales, Chiara Bardella, Chunjie Li, Cristina Escribano-Gonzalez, Alpesh Thakker, Yannic Nonnenmacher, Katarina Kluckova, Mark Jeeves, Robert Murren, Federica Cuozzo, Dan Ye, Giulio Laurenti, Wei Zhu, Karsten Hiller, David J. Hodson, Wei Hua, Ian P. Tomlinson, Christian Ludwig, Ying Mao, Daniel A. Tennant
Publikováno v:
Cell Reports, Vol 22, Iss 12, Pp 3107-3114 (2018)
Summary: Since the discovery of mutations in isocitrate dehydrogenase 1 (IDH1) in gliomas and other tumors, significant efforts have been made to gain a deeper understanding of the consequences of this oncogenic mutation. One aspect of the neomorphic
Externí odkaz:
https://doaj.org/article/26706adfa2534c22a56f1079550fabca
Autor:
Simon J. McIlroy, Cristobal A. Onetto, Bianca McIlroy, Florian-Alexander Herbst, Morten S. Dueholm, Rasmus H. Kirkegaard, Eustace Fernando, Søren M. Karst, Marta Nierychlo, Jannie M. Kristensen, Kathryn L. Eales, Paul R. Grbin, Reinhard Wimmer, Per Halkjær Nielsen
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Enhanced biological phosphorus removal (EBPR) involves the cycling of biomass through carbon-rich (feast) and carbon-deficient (famine) conditions, promoting the activity of polyphosphate accumulating organisms (PAOs). However, several alternate meta
Externí odkaz:
https://doaj.org/article/4d97d385e3184012a48e99703a6d7b23
Akademický článek
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Autor:
Rebecca L. Westbrook, Esther Bridges, Jennie Roberts, Cristina Escribano-Gonzalez, Katherine L. Eales, Lisa A. Vettore, Paul D. Walker, Elias Vera-Siguenza, Himani Rana, Federica Cuozzo, Kattri-Liis Eskla, Hans Vellama, Abeer Shaaban, Colin Nixon, Hendrik Luuk, Gareth G. Lavery, David J. Hodson, Adrian L. Harris, Daniel A. Tennant
Publikováno v:
Cell reports. 38(5)
The demands of cancer cell proliferation alongside an inadequate angiogenic response lead to insufficient oxygen availability in the tumor microenvironment. Within the mitochondria, oxygen is the major electron acceptor for NADH, with the result that
Autor:
Katherine L. Eales, Edward A. Wilkinson, Garth Cruickshank, James H. R. Tucker, Daniel A. Tennant
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Gliomas are highly malignant brain tumours characterised by extensive areas of poor perfusion which subsequently leads to hypoxia and reduced survival. Therapies that address the hypoxic microenvironment are likely to significantly improve patient ou
Autor:
Ying Mao, Ian Tomlinson, Dan Ye, Federica Cuozzo, Haydn Munford, Daniel A. Tennant, Giulio Laurenti, Robert Murren, Yannic Nonnenmacher, Katarina Kluckova, Katherine L. Eales, Mark Jeeves, Kate E.R. Hollinshead, Wei Hua, Karsten Hiller, Christian Ludwig, Wei Zhu, David J. Hodson, Alpesh Thakker, Chiara Bardella, Cristina Escribano-Gonzalez, Chunjie Li
Publikováno v:
Cell Reports, Vol 22, Iss 12, Pp 3107-3114 (2018)
Hollinshead, K E R, Munford, H, Eales, K L, Bardella, C, Li, C, Escribano-Gonzalez, C, Thakker, A, Nonnenmacher, Y, Kluckova, K, Jeeves, M, Murren, R, Cuozzo, F, Ye, D, Laurenti, G, Zhu, W, Hiller, K, Hodson, D J, Hua, W, Tomlinson, I P, Ludwig, C, Mao, Y & Tennant, D A 2018, ' Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis ', Cell Reports, vol. 22, no. 12, pp. 3107-3114 . https://doi.org/10.1016/j.celrep.2018.02.084
Cell Reports
Hollinshead, K E R, Munford, H, Eales, K L, Bardella, C, Li, C, Escribano-Gonzalez, C, Thakker, A, Nonnenmacher, Y, Kluckova, K, Jeeves, M, Murren, R, Cuozzo, F, Ye, D, Laurenti, G, Zhu, W, Hiller, K, Hodson, D J, Hua, W, Tomlinson, I P, Ludwig, C, Mao, Y & Tennant, D A 2018, ' Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis ', Cell Reports, vol. 22, no. 12, pp. 3107-3114 . https://doi.org/10.1016/j.celrep.2018.02.084
Cell Reports
Summary Since the discovery of mutations in isocitrate dehydrogenase 1 (IDH1) in gliomas and other tumors, significant efforts have been made to gain a deeper understanding of the consequences of this oncogenic mutation. One aspect of the neomorphic
Akademický článek
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Akademický článek
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Publikováno v:
Neuro-oncology Advances
Advancements in prevention, detection and treatment over the last 40 years have significantly transformed cancer healthcare however there are a few cancers, such as brain tumours, which are consistently lagging behind. The most common adult brain tum
Publikováno v:
Systematic and Applied Microbiology. 40:396-399
An industrial wastewater treatment plant (WWTP) in Australia has long suffered from bulking problems associated with the proliferation of Thiothrix spp. The WWTP consists of a covered anaerobic lagoon (CAL) followed by a sequencing batch reactor (SBR