Výsledky vyhledávání - "L. E. Silberstein"

VH4.21-encoded natural autoantibodies with anti-i specificity mirror those associated with cold hemagglutinin disease

Autor: M E Schutte, J H van Es, L E Silberstein, T Logtenberg

Publikováno v: The Journal of Immunology. 151:6569-6576

The Ig VH regions of virtually all human pathogenic cold agglutinin (CA) anti-i/l autoantibodies are encoded by a single Ig VH gene segment, VH4.21, in conjunction with a highly variable CDR3 structure. The anti-I specificity is often associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e0d86a291da4671e32b78fd5ba8de6a
https://doi.org/10.4049/jimmunol.151.11.6569

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Structural basis of a conserved idiotope expressed by an autoreactive human B cell lymphoma. Evidence that a VH CDR3 mutation alters idiotypy and specificity

Autor: L S Reidl, D F Friedman, J Goldman, R R Hardy, L C Jefferies, L E Silberstein

Publikováno v: The Journal of Immunology. 147:3623-3631

Our laboratory has previously investigated the relationship of autoimmune disease and B cell neoplasia in a patient with a diffuse, well differentiated splenic B cell lymphoma and associated autoimmune hemolysis due to an anti-Pr2 antibody. EBV-immor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4942129c762500832f247725881503ad
https://doi.org/10.4049/jimmunol.147.10.3623

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Variation in blood component irradiation practice: implications for prevention of transfusion-associated graft-versus-host disease

Autor: K C, Anderson, L T, Goodnough, M, Sayers, P T, Pisciotto, S R, Kurtz, T A, Lane, C S, Anderson, L E, Silberstein

Publikováno v: Blood. 77:2096-2102

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2d9780f244fa7cbf1b014e3bf32039
https://doi.org/10.1182/blood.v77.10.2096.2096

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16Cys encoded by the RHce gene is associated with altered expression of the e antigen and is frequent in the R0 haplotype

Autor: C M, Westhoff, L E, Silberstein, D E, Wylie, M, Skavdahl, M E, Reid

Publikováno v: British journal of haematology. 113(3)

Serological observations have suggested that numerous D, many e (especially in Blacks), several E, and rare c variants exist within the Rh blood group system. The molecular basis for expression of many of these variants has been elucidated. This stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca1771cd206d117d6d9c7abcf00cdf72
https://pubmed.ncbi.nlm.nih.gov/11380456

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Evidence that immunoglobulin specificities of AIDS-related lymphoma are not directed to HIV-related antigens

Autor: G, Cunto-Amesty, G, Przybylski, M, Honczarenko, J G, Monroe, L E, Silberstein

Publikováno v: Blood. 95(4)

Chronic B-cell stimulation may be a predisposing event in the early pathogenesis of the acquired immunodeficiency syndrome (AIDS)-related lymphoma (ARL). ARL-derived immunoglobulin (Ig) genes are significantly diversified from germline, suggesting th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::de9c562c44c532b46e65a7b5a0e2f60f
https://pubmed.ncbi.nlm.nih.gov/10666216

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SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells

Autor: M, Honczarenko, R S, Douglas, C, Mathias, B, Lee, M Z, Ratajczak, L E, Silberstein

Publikováno v: Blood. 94(9)

Chemokines and their receptors are broadly expressed in different tissues and are involved in diverse biologic processes. Gene inactivation studies have shown that both stromal cell derived factor-1 (SDF-1) and chemokine receptor 4 (CXCR4) are essent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1355030a4294af075d4fa0200f4c2e61
https://pubmed.ncbi.nlm.nih.gov/10556181

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Biased VH gene usage in early lineage human B cells: evidence for preferential Ig gene rearrangement in the absence of selection

Autor: S P, Rao, J M, Riggs, D F, Friedman, M S, Scully, T W, LeBien, L E, Silberstein

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(5)

Certain VH genes are predominantly expressed in mature B cells. We hypothesized that several, mutually nonexclusive VH-dependent mechanisms operating at distinct stages during B cell development may be responsible for overrepresentation of these VH g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::844831049487f39068ff669eaa16938c
https://pubmed.ncbi.nlm.nih.gov/10453015

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Evidence for early B-cell activation preceding the development of Epstein-Barr virus-negative acquired immunodeficiency syndrome-related lymphoma

Autor: G K, Przybylski, J, Goldman, V L, Ng, M S, McGrath, B G, Herndier, D P, Schenkein, J G, Monroe, L E, Silberstein

Publikováno v: Blood. 88(12)

To investigate the origin and pathogenesis of acquired immunodeficiency syndrome (AIDS)-related lymphoma (ARL), we studied 14 cases in which Epstein-Barr virus (EBV) infection was not an etiologic factor. By histology, 8 of the specimens were of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::05a7d8e8275919aaaa9f64799e2108b1
https://pubmed.ncbi.nlm.nih.gov/8977254

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Heteroduplex generator in analysis of Rh blood group alleles

Autor: J, Stoerker, C, Hurwitz, N C, Rose, L E, Silberstein, W E, Highsmith

Publikováno v: Clinical chemistry. 42(3)

We describe the use of heteroduplex analysis to enhance the resolution of different rhesus-derived (Rh) isotypes. Heteroduplex analysis of different domains of the Rh D and Rh CE loci can be performed to diagnose a variety of blood group incompatibil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84b4535c7d0204d051758b0ce70cbaf5
https://pubmed.ncbi.nlm.nih.gov/8598095

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