Zobrazeno 1 - 10
of 12
pro vyhledávání: '"L. E. Schechter"'
Autor:
C E, Beyer, Q, Lin, B, Platt, J, Malberg, G, Hornby, K M, Sullivan, D L, Smith, T, Lock, P J, Mitchell, N T, Hatzenbuhler, D A, Evrard, B L, Harrison, R, Magolda, M N, Pangalos, L E, Schechter, S, Rosenzweig-Lipson, T H, Andree
Publikováno v:
British journal of pharmacology. 157(2)
As a combination of 5-HT selective reuptake inhibitor (SSRI) with 5-HT(1A) receptor antagonism may yield a rapidly acting antidepressant, WAY-211612, a compound with both SSRI and 5-HT(1A) receptor antagonist activities, was evaluated in preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::636cfa6fa426239f78461e717e08ba25
https://pubmed.ncbi.nlm.nih.gov/19338583
https://pubmed.ncbi.nlm.nih.gov/19338583
Publikováno v:
British journal of pharmacology. 130(4)
Using in vivo microdialysis in the frontal cortex of the freely moving rat we evaluated the effects of chronic treatment with the serotonin specific reuptake inhibitor (SSRI) fluoxetine in the presence and absence of the 5-HT(1A)/beta-adrenergic anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc41d20f52496db8f1dd8debd390f290
https://pubmed.ncbi.nlm.nih.gov/10864885
https://pubmed.ncbi.nlm.nih.gov/10864885
Autor:
L. E. Schechter
Publikováno v:
CNS Drug Reviews. 6:13-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467ba2924658c258b6c8993313d44982
https://doi.org/10.1111/j.1527-3458.2000.tb00165.x
https://doi.org/10.1111/j.1527-3458.2000.tb00165.x
Autor:
L E, Schechter
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(1)
Previous investigations have demonstrated that compounds capable of blocking presynaptic potassium channels can stimulate neurotransmitter release at both peripheral and central synapses. This study examined the in vitro effects of the "classical" po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bd2ce59b40c7bce11c8d5f3f7e503ad
https://pubmed.ncbi.nlm.nih.gov/9223563
https://pubmed.ncbi.nlm.nih.gov/9223563
Autor:
K J, Rhodes, M M, Monaghan, N X, Barrezueta, S, Nawoschik, Z, Bekele-Arcuri, M F, Matos, K, Nakahira, L E, Schechter, J S, Trimmer
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(16)
Recent cloning of K+ channel beta subunits revealed that these cytoplasmic polypeptides can dramatically alter the kinetics of current inactivation and promote efficient glycosylation and surface expression of the channel-forming alpha subunits. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95febc3511dc57ae68d16ea3b862f7da
https://pubmed.ncbi.nlm.nih.gov/8756417
https://pubmed.ncbi.nlm.nih.gov/8756417
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 354(3)
Recombinant human 5-HT1D alpha and 5-HT1D beta receptor subtypes were stably expressed in NIH-3T3 fibroblasts (1D alpha cell line) and Y-1 adrenocortical tumor cells (1D beta cell line), respectively, for pharmacological evaluations of serotonergic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5a770a8a4d696656dd7f3684ceaefdd
https://pubmed.ncbi.nlm.nih.gov/8878051
https://pubmed.ncbi.nlm.nih.gov/8878051
Autor:
N Adham, Thomas M. Laz, P. J.-J. Vaysse, J. A. Bard, L E Schechter, H T Kao, C Gerald, T A Branchek, M A Olsen, Paul R. Hartig
Molecular cloning efforts have provided primary amino acid sequence and signal transduction data for a large collection of serotonin receptor subtypes. These include five 5-HT1-like receptors, three 5-HT2 receptors, one 5-HT3 receptor, two 5-HT5 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74627b5dbbc9087df24cbc21300b271
https://europepmc.org/articles/PMC398399/
https://europepmc.org/articles/PMC398399/
Autor:
H.-T. Kao, N. Adham, Richard L. Weinshank, P. R. Hartig, L E Schechter, Theresa A. Branchek, M. Macchi, J M Zgombick
Publikováno v:
Clinical Pharmacology in Psychiatry ISBN: 9783642780127
The fact that nearly all known serotonin receptor subtypes are single subunit proteins, members of the same gene superfamily (the G protein-coupled receptor or 7TM superfamily) and that most are intronless genes has helped accelerate the cloning of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11246793ec3ea25d0ef93a557eb79d11
https://doi.org/10.1007/978-3-642-78010-3_3
https://doi.org/10.1007/978-3-642-78010-3_3
Publikováno v:
Molecular pharmacology. 42(2)
The gene encoding a human 5-hydroxytryptamine (5-HT)1 receptor subtype was isolated from a human placental genomic library by using oligonucleotide probes derived from transmembrane regions of the cloned human 5-HT1D beta receptor. The deduced amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4602a844d176fb672a614d8c33de210a
https://pubmed.ncbi.nlm.nih.gov/1513320
https://pubmed.ncbi.nlm.nih.gov/1513320
Publikováno v:
Molecular pharmacology. 40(6)
RDC4 is a guanine nucleotide-binding protein-coupled receptor clone originally isolated from a canine thyroid cDNA library by Libert and colleagues [Science (Washington D. C.) 244:569-572 (1989)]. We have isolated the corresponding genomic clone for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dcdb00fdfcd942df5583f0396b3bfec
https://pubmed.ncbi.nlm.nih.gov/1758439
https://pubmed.ncbi.nlm.nih.gov/1758439