Zobrazeno 1 - 10
of 24
pro vyhledávání: '"L. E. Rikans"'
Autor:
K R Hornbrook, L E Rikans
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1362:116-127
The free radical hypothesis of aging proposes that deleterious actions of oxygen-derived radicals are responsible for the functional deterioration associated with aging. Because cellular membranes house the production apparatus of these radicals and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02afceedf378870ff2f6c6d4cfb9efdb
https://doi.org/10.1016/s0925-4439(97)00067-7
https://doi.org/10.1016/s0925-4439(97)00067-7
Autor:
L E, Rikans, T, Yamano
Publikováno v:
Journal of biochemical and molecular toxicology. 14(2)
The mechanism of cadmium-mediated acute hepatotoxicity has been the subject of numerous investigations and although some uncertainties persist, sufficient evidence has emerged to provide a reasonable account of the toxic process. Acute hepatotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf93c2dd5fa9c8ecb20ac4f0f684ac1
https://pubmed.ncbi.nlm.nih.gov/10630425
https://pubmed.ncbi.nlm.nih.gov/10630425
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(4)
The aim of this study was to determine the influence of aging on diquat-induced redox cycling in liver microsomes and diquat hepatotoxicity in rats. Diquat-stimulated production of superoxide anion radical and NADPH-cytochrome c (P-450) reductase act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd2f77fe9074d5bfce63d21de5acc870
https://pubmed.ncbi.nlm.nih.gov/8104118
https://pubmed.ncbi.nlm.nih.gov/8104118
Autor:
L E, Rikans, Y, Cai
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(1)
The effect of age on the toxicity of diquat, a redox cycling compound, was investigated in hepatocytes isolated from mature (6 months) and old (24-29 months) male Fischer 344 rats. Hepatocytes of old rats were more sensitive than those of mature rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f674222f12aba11a4da2f8c4d2d40f9e
https://pubmed.ncbi.nlm.nih.gov/1320687
https://pubmed.ncbi.nlm.nih.gov/1320687
Publikováno v:
Oklahoma Notes ISBN: 9780387977799
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c168969d587fc07a714588c49008e3c
https://doi.org/10.1007/978-1-4684-0524-8_6
https://doi.org/10.1007/978-1-4684-0524-8_6
Publikováno v:
Oklahoma Notes ISBN: 9780387977799
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e30c5e1cd684a7258f8b534063dbf27
https://doi.org/10.1007/978-1-4684-0524-8_7
https://doi.org/10.1007/978-1-4684-0524-8_7
Publikováno v:
Oklahoma Notes ISBN: 9780387971940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d51d382a1b178fec32f7b050751cd448
https://doi.org/10.1007/978-1-4684-0353-4_1
https://doi.org/10.1007/978-1-4684-0353-4_1
Publikováno v:
Oklahoma Notes ISBN: 9780387971940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::989487c0677daf513f2efaf0e7596cc1
https://doi.org/10.1007/978-1-4684-0353-4_6
https://doi.org/10.1007/978-1-4684-0353-4_6
Publikováno v:
Oklahoma Notes ISBN: 9780387971940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a08dedd37c50f08de53b42a4b0831f6e
https://doi.org/10.1007/978-1-4684-0353-4_7
https://doi.org/10.1007/978-1-4684-0353-4_7
Publikováno v:
Oklahoma Notes ISBN: 9780387971940
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63136ece0d220c4ce6e7dccc1601e746
https://doi.org/10.1007/978-1-4684-0353-4_3
https://doi.org/10.1007/978-1-4684-0353-4_3