Výsledky vyhledávání - "L. E. Phillips"

TRAIL responses are enhanced by nuclear export inhibition in osteosarcoma

Autor: E. McDermott, Kate L E Phillips, Nicola Wright, Neil Cross

Publikováno v: Biochemical and biophysical research communications. 517(2)

Tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is a promising anti-tumour agent that induces apoptosis of malignant cells through activation of death receptors. Death receptor agonistic antibodies are in clinical trials as TRAIL-mim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d143c488cb5f4ad5838af8c4d56d9a
https://pubmed.ncbi.nlm.nih.gov/31362889

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Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes

Autor: Rowena A.D. Bunning, C. L. Le Maitre, Ashley Cole, Neil Chiverton, K. Cullen, Lee Breakwell, Kate L E Phillips, A. R. Michael, Gail Haddock, Alison K. Cross

Publikováno v: Osteoarthritis and Cartilage. 23(7):1165-1177

Summary Objective These studies investigated cytokine and chemokine receptor profiles in nucleus pulposus (NP) cells, and the effects of receptor stimulation on mRNA levels of extracellular matrix (ECM) components, degrading enzymes and cytokine and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d93a27fb10d6c501f5e68c033d37a46e

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CCL21 and Dendritic Cell Suppression in Paediatric B Cell Acute Lymphoblastic Leukaemia

Autor: Kate L E Phillips, Russell Keenan

Publikováno v: Blood. 134:3959-3959

Despite the accumulation of genetic mutations likely to generate antigenic neoepitopes, acute lymphoblastic leukaemia (ALL) cells are poor at eliciting anti-tumour immune responses. Similarly to dendritic cells (DCs), B cells have antigen presenting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dad20b6bb6a043a17673bdcf78872488
https://doi.org/10.1182/blood-2019-130093

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Inflammatory Cytokines Induce NOTCH Signaling in Nucleus Pulposus Cells

Autor: Kate L E Phillips, Abbie L. A. Binch, Zhaomin Zheng, Jianru Wang, Christine L. Le Maitre, Alison K. Cross, Ye Tian, Sara L Dunn, Irving M. Shapiro, Hua Wang, Neil Chiverton, Makarand V. Risbud

Publikováno v: Journal of Biological Chemistry. 288:16761-16774

The objective of the study was to investigate how inflammatory cytokines, IL-1β, and TNF-α control NOTCH signaling activity in nucleus pulposus (NP) cells. An increase in expression of selective NOTCH receptors (NOTCH1 and -2), ligand (JAGGED2), an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0cfbccae66b4cb409e805d6839ca969
https://doi.org/10.1074/jbc.m112.446633

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Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1

Autor: Alison K. Cross, Kate L E Phillips, Gail Haddock, Neil Chiverton, Christine L. Le Maitre, Rowena A.D. Bunning, Ye Tian, Makarand V. Risbud, Jianru Wang, Irving M. Shapiro

Publikováno v: Arthritis & Rheumatism. 65:832-842

Objective. To investigate tumor necrosis factor α (TNF α) and interleukin-1β (IL-1 β) regulation of CCL3 expression in nucleus pulposus (NP) cells and in macrophage migration. Methods. Quantitative reverse transcription polymerase chain reaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47c2b7fa639d1dd004b434100147036
https://doi.org/10.1002/art.37819

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Improving outcomes for hospital patients with critical bleeding requiring massive transfusion: the Australian and New Zealand Massive Transfusion Registry study methodology

Autor: K. M. Venardos, James P. Isbister, Erica M. Wood, N. J. Aoki, Nick Andrianopoulos, A. J. Zatta, Peter Cameron, Zoe McQuilten, L. E. Phillips, John Oldroyd, D. J. Cooper

Publikováno v: Scopus-Elsevier
BMC Research Notes

Background: The Australian and New Zealand (ANZ) Massive Transfusion (MT) Registry (MTR) has been established to improve the quality of care of patients with critical bleeding (CB) requiring MT (≥ 5 units red blood cells (RBC) over 4 h). The MTR is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413e5aca48e1795f173ec6023e14a189
https://doi.org/10.1186/s13104-016-2261-6

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Evaluation of clinical coding data to determine causes of critical bleeding in patients receiving massive transfusion: a bi-national, multicentre, cross-sectional study

Autor: Z K, McQuilten, A J, Zatta, N, Andrianopoulos, N, Aoki, L, Stevenson, K G, Badami, R, Bird, M F, Cole-Sinclair, C, Hurn, P A, Cameron, J P, Isbister, L E, Phillips, E M, Wood

Publikováno v: Transfusion medicine (Oxford, England). 27(2)

To evaluate the use of routinely collected data to determine the cause(s) of critical bleeding in patients who receive massive transfusion (MT).Routinely collected data are increasingly being used to describe and evaluate transfusion practice.Chart r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fded0a2a9a1d6ea663c848850a3f245
https://pubmed.ncbi.nlm.nih.gov/27966239

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Locating the type specimens of New Zealand marine algae described by Levring

Autor: L. E. Phillips, Wendy A. Nelson

Publikováno v: New Zealand Journal of Botany. 39:349-353

Sixteen marine macroalgae from New Zealand were described by Tore Levring in two papers in 1949 and 1955. From the time of publication there has been confusion about the location and the identity of type material of the taxa Levring described. Althou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94e2bc7df0b1bde23ba9612444bccb3c
https://doi.org/10.1080/0028825x.2001.9512740

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