Zobrazeno 1 - 10
of 25
pro vyhledávání: '"L. E. Diamond"'
Autor:
David J, Saxby, Bryce Adrian, Killen, C, Pizzolato, C P, Carty, L E, Diamond, L, Modenese, J, Fernandez, G, Davico, M, Barzan, G, Lenton, S Brito, da Luz, E, Suwarganda, D, Devaprakash, R K, Korhonen, J A, Alderson, T F, Besier, R S, Barrett, D G, Lloyd
Publikováno v:
Biomechanics and modeling in mechanobiology. 19(4)
Many biomedical, orthopaedic, and industrial applications are emerging that will benefit from personalized neuromusculoskeletal models. Applications include refined diagnostics, prediction of treatment trajectories for neuromusculoskeletal diseases,
Publikováno v:
International Journal of Impotence Research. 16:135-142
PT-141, a cyclic heptapeptide melanocortin analog, was evaluated following subcutaneous administration to healthy male subjects and to patients with erectile dysfunction (ED) who report an inadequate response to Viagra. An inadequate response was def
Publikováno v:
International Journal of Impotence Research. 16:51-59
PT-141, a cyclic heptapeptide melanocortin analog, was evaluated following intranasal administration in healthy male subjects and in Viagra-responsive erectile dysfunction (ED) patients. Erectile response was assessed by RigiScan trade mark in health
Publikováno v:
Annals of the New York Academy of Sciences. 994:96-102
PT-141, a synthetic peptide analogue of alpha-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R, which are expressed primarily in the central nervous system. Administration of PT-141 to rats and nonhuman primates results in pen
Autor:
Sara A. J. Thompson, John S. Logan, Masahide Tone, Yukiko Tone, Louise Walsh, Herman Waldmann, L E Diamond, Elizabeth M. Shanahan
Publikováno v:
Journal of Biological Chemistry. 274:710-716
CD59 is a complement regulatory protein and may also act as a signal-transducing molecule. CD59 transgenic mice have been generated using a CD59 minigene (CD59 minigene-1). Although this minigene contained a 4.6-kilobase pair 5'-flanking region from
Publikováno v:
Molecular and Cellular Biology. 10:1265-1269
The DNA sequence of the c-myc-regulated gene mrl (G. C. Prendergast and M. D. Cole, Mol. Cell. Biol. 9:124-134, 1989) reveals that it encodes plasminogen activator inhibitor 1 (PAI-1), a regulator of extracellular proteolysis. Comparison of the human
Autor:
John S. Logan, L E Diamond, Guerard W. Byrne, Patrick G. Dean, Mark D. Stegall, Cga McGregor, Ari J. Cohen, H Dalla Valle, J.P Grande
Publikováno v:
Transplantation proceedings. 33(1-2)
Autor:
S S, Lin, M J, Hanaway, G V, Gonzalez-Stawinski, C L, Lau, W, Parker, R D, Davis, G W, Byrne, L E, Diamond, J S, Logan, J L, Platt
Publikováno v:
Transplantation. 70(12)
A major impediment to the transplanting of porcine organs into humans is the susceptibility of porcine organs to acute vascular rejection, which can destroy a vascularized xenograft over a period of hours to days. Acute vascular rejection of porcine-
Autor:
M F, Levy, J, Crippin, S, Sutton, G, Netto, J, McCormack, T, Curiel, R M, Goldstein, J T, Newman, T A, Gonwa, J, Banchereau, L E, Diamond, G, Byrne, J, Logan, G B, Klintmalm
Publikováno v:
Transplantation. 69(2)
Whole organ extracorporeal perfusion of a genetically modified humanized (transgenic) pig liver has been proposed as a technology that may sustain patients with severe liver failure while awaiting human liver transplantation.We report on two cases of
Publikováno v:
Xenotransplantation. 6(3)
We have previously created transgenic pigs bearing the human complement regulatory proteins CD59 and decay-accelerating factor (DAF) by either the intercellular transfer or the cDNA transgenic method. To achieve more physiologic protein expression, w