Zobrazeno 1 - 10
of 41
pro vyhledávání: '"L. E. Babiss"'
Publikováno v:
Journal of Virology. 66:1884-1890
Tumorigenesis is a multistep process involving both genetic and epigenetic changes resulting in altered cellular gene expression. While many phenotypic attributes of transformed cells have been described, the cellular genes responsible for these phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1a2962c4b3504c18f465d095144f6f
https://doi.org/10.1128/jvi.66.4.1884-1890.1992
https://doi.org/10.1128/jvi.66.4.1884-1890.1992
Autor:
L E Babiss, Guy R. Adami
Publikováno v:
Molecular and Cellular Biology. 12:1630-1638
By in vitro analysis, the major late promoter (MLP) of adenovirus has been shown to be a simple promoter requiring two elements for efficient transcription: a minimal promoter element (MPE), where the general transcription factor-polymerase II comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42452c72e185375ea932fa90ecf0ae36
https://doi.org/10.1128/mcb.12.4.1630
https://doi.org/10.1128/mcb.12.4.1630
Publikováno v:
The EMBO Journal. 10:4169-4175
Changes in MHC class I expression are frequently observed in tumors, which represents at least one mechanism by which tumor cells escape immune surveillance. MHC class I expression is often suppressed in type 12 adenovirus (Ad12)-transformed rodent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7fb9b70661385d2fbc0ea655f3dd481
https://doi.org/10.1002/j.1460-2075.1991.tb04995.x
https://doi.org/10.1002/j.1460-2075.1991.tb04995.x
Autor:
Guy R. Adami, L E Babiss
Publikováno v:
The EMBO Journal. 10:3457-3465
Many cellular and viral genes are parts of complex transcription units containing multiple splicing choices. During the course of an adenoviral replicative cycle, different spliced versions of a single gene predominate, depending on the stage of infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44b718101c7e39705ff3982320e71a8
https://doi.org/10.1002/j.1460-2075.1991.tb04910.x
https://doi.org/10.1002/j.1460-2075.1991.tb04910.x
Autor:
L E Babiss, Jeffrey M. Friedman
Publikováno v:
Molecular and Cellular Biology. 10:6700-6708
We present evidence that differences in the levels of N-myc mRNA among different cell types are the result of posttranscriptional control. First, we noted that while steady-state mouse N-myc mRNA could be detected only in fetal mouse brain, it was tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2bfbece06c24a042ce6355269478533
https://doi.org/10.1128/mcb.10.12.6700
https://doi.org/10.1128/mcb.10.12.6700
Publikováno v:
Molecular and Cellular Biology. 10:3896-3905
The far-upstream mouse albumin enhancer (-10.5 to -8.43 kilobases) has both positive and negative regulatory domains which contribute to the rate and tissue specificity of albumin gene transcription. (R. S. Herbst, N. Friedman, J. E. Darnell, Jr., an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e0cecd709c8325593af3ee5d7b9923
https://doi.org/10.1128/mcb.10.8.3896-3905.1990
https://doi.org/10.1128/mcb.10.8.3896-3905.1990
Publikováno v:
Journal of Virology. 64:161-172
Most of the eucaryotic enhancer elements so far described consist of multiple DNA binding sites for proteins that act either synergistically or antagonistically to modulate the rate of transcription. In this report, we show that the activity of the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d6b481b928522de186b1043af6a23b
https://doi.org/10.1128/jvi.64.1.161-172.1990
https://doi.org/10.1128/jvi.64.1.161-172.1990
Publikováno v:
Journal of Cellular Biochemistry. 42:33-44
Mutants of type 5 adenovirus that lack all or part of the early region IA(EIA) gene enhancer element transform rodent embryo fibroblast (CREF) cells at higher efficiencies than wild-type virus. An analysis of viral E1A cytoplasmic mRNA levels in muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1971faf816eb7c07c61118963a12fb
https://doi.org/10.1002/jcb.240420104
https://doi.org/10.1002/jcb.240420104
Publikováno v:
Combinatorial chemistryhigh throughput screening. 9(2)
The process of Drug Discovery is a complex and high risk endeavor that requires focused attention on experimental hypotheses, the application of diverse sets of technologies and data to facilitate high quality decision-making. All is aimed at enhanci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7eaa66bcf9bc13e5577559159e9c00
https://pubmed.ncbi.nlm.nih.gov/16475967
https://pubmed.ncbi.nlm.nih.gov/16475967
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 6(9)
The misregulation of cell cycle checkpoints has been implicated in the onset of neoplasia. To thoroughly understand the differences in checkpoint regulation between normal and transformed cells, we have compared the cell cycle responses of normal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9768bb65d9f79b266259e475b06e015
https://pubmed.ncbi.nlm.nih.gov/8519681
https://pubmed.ncbi.nlm.nih.gov/8519681