Spectral Properties of Topical Retinoids Prevent DNA Damage and Apoptosis After Acute UV-B Exposure in Hairless Mice¶

Autor: L. Didierjean, Ambros Hügin, Jean-Hilaire Saurat, Christian Tran, Olivier Sorg, Denise Grand, Pierre Carraux

Publikováno v: Photochemistry and Photobiology. 81:830-836

We showed in a recent study that topical retinyl palmitate prevented UV-B-induced DNA damage and erythema in humans. Given that retinyl palmitate is a precursor of retinoic acid, the biological form of vitamin A that acts through nuclear receptors, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22893b6fd168cbb263a501d28c51cbc6
https://doi.org/10.1111/j.1751-1097.2005.tb01450.x

Oxidative Stress-Independent Depletion of Epidermal Vitamin A by UVA

Autor: Christian Tran, Olivier Sorg, L. Didierjean, Françoise Falson, Pierre Carraux, Jean-Hilaire Saurat

Publikováno v: Journal of Investigative Dermatology. 118(3):513-518

In hairless mice, epidermal vitamin A (retinol and retinyl esters) is strongly decreased following a single exposure to UVB. Here, using the same mouse model, we studied the effects of UVA on epidermal vitamin A content, lipid peroxidation, and CRBP-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ab1ced6b60ff53774ee5767a8c0e0d

Topical 9-cis-retinaldehyde for delivery of 9-cis-retinoic acid in mouse skin

Autor: J. O. Sass, C. Plum, Denise Grand, Pierre Carraux, Olivier Sorg, J.-H. Saurat, Heinz Nau, L. Didierjean

Publikováno v: Experimental Dermatology. 8:199-203

The 9-cis-retinoic acid (9cRA) is an endogenous ligand of retinoid X nuclear receptors (RXRs). Although the epidermis contains five times more RXRs than RARs, little is known on the activity of topical 9cRA. In order to circumvent surface isomerizati

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https://doi.org/10.1111/j.1600-0625.1999.tb00371.x

Contents, Vol. 191, 1995

Autor: Y. Shigenaga, M. Harms, I. Masouyé, B. Didona, R. Happle, E. Svejgaard, T. Kanzaki, A. Fiedler, P. Elsner, C. Willa-Craps, J.-H. Saurat, L. Didierjean, J. Sayag, G. Dawn, R. Hoffmann, P.H. Itin, C. Gelmetti, H.C. Korting, I. Braide, I. Ikeda, H. Ogawa, P.A. Piletta, R. Schultheiss, M. Yoshioka, M.C. Koeppel, E. Frenk, M. Yamazaki, T. Ono, T. Hisa, C. Mazzanti, C. Angeli-Besson, J.-M. Geiger, T. Kageshita, M.-H. Schmid, T. Fukumitsu, A.J. Kanwar, U.-F. Haustein, S. Ullman, P. Fileccia, D. Hohl, M.A. Fernández-Pugnaire, S. Mizoguchi, C. Nishikawa, C.R. Çelebi, T. Hamada, N. Kürkçüoğlu, T. Hunziker, T. Gobello, L. Andrac, R. Ammann, D. Guggisberg, V. Delgado-Florencio, S. Dhar, K. Rosén, K. Unno, M. Yssing, S. Cambiaghi, T. Rufli, T. Horio, C. Remondat, G. Scarabelli, B. Vion, H. Yaguchi, G. Pistritto, H. Miyauchi, P. Jacquet, A.M. Calza, C. Bertrand, G. Burg, S.A. Buechner, T. Karlsmark, I. Katayama, C. Hansson, C. Schepis, T. Yamamoto, M. Pechère, F. Atzori, K. Nishioka, R. Cavalieri, R. Tsuboi, N. Illum, M. Takigawa, P. Nenoff, M. Papi, M. Siragusa, Y. Hirachi, M. Setoyama, L.R. Braathen, P. Blecher

Publikováno v: Dermatology. 191:I-VI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a6eb20dfa0d96880884497f614859de
https://doi.org/10.1159/000246566

Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro

Autor: Raymonde Hotz, L. Didierjean, Georges Siegenthaler, Jean-Hilaire Saurat, Ulf Hellman, D Chatellard-Gruaz

Publikováno v: Biochemical Journal. 302:363-371

Epidermal fatty acid-binding protein (E-FABP) was isolated from human skin and purified to homogeneity. Its molecular mass was estimated to be 15 kDa and the pI of non-denaturing protein was 5.6. Scatchard-plot analysis revealed one class of binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4bac37dca554354cf894ea6bea92b55
https://doi.org/10.1042/bj3020363