Zobrazeno 1 - 10
of 498
pro vyhledávání: '"L. Daugherty"'
Autor:
Monika Chauhan, Audrey L. Daugherty, Fatemeh (Ellie) Khadir, Ozgun F. Duzenli, Alexandra Hoffman, Jennifer A. Tinklenberg, Peter B. Kang, George Aslanidi, Christina A. Pacak
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Highly efficient adeno associated viruses (AAVs) targeting the central nervous system (CNS) are needed to deliver safe and effective therapies for inherited neurological disorders. The goal of this study was to compare the organ-specific tra
Externí odkaz:
https://doaj.org/article/cafeb29b8b2c4e6c854217899ac3adad
Autor:
Christina A. Pacak, Silveli Suzuki-Hatano, Fatemeh Khadir, Audrey L. Daugherty, Mughil Sriramvenugopal, Bennett J. Gosiker, Peter B. Kang, William Todd Cade
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Introduction The promising potential of adeno-associated virus (AAV) gene delivery strategies to treat genetic disorders continues to grow with an additional three AAV-based therapies recently approved by the Food and Drug Administration and
Externí odkaz:
https://doaj.org/article/f69833ae695641cf9607659cc8cf2067
Autor:
Grace Zhao, Timothy C Wang, Mingfa Zang, Jin Qian, Bruce L Daugherty, Seth Lederman, Rebecca J Boohaker, Rebecca Johnstone, Karr Stinson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9cfbdd1faa97408a8d3fbdab5140a4d5
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e6ff1a0b05e54862a4b42330f7f35bb4
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4373e684847c41f18097684d5ddfd0d9
This book helps secondary life science teachers who are receptive to engineering ideas but struggle to develop age-appropriate, standards-based lessons. Offers open-ended design challenges for presenting engineering concepts in quick, engaging ways.
Autor:
Christine C. Bruels, Hannah R. Littel, Audrey L. Daugherty, Seth Stafki, Elicia A. Estrella, Emily S. McGaughy, Don Truong, Jonathan P. Badalamenti, Lynn Pais, Vijay S. Ganesh, Anne O'Donnell‐Luria, Heather J. Stalker, Yang Wang, Christin Collins, Andrea Behlmann, Richard J. L. F. Lemmers, Silvère M. van derMaarel, Regina Laine, Partha S. Ghosh, Basil T. Darras, Carla D. Zingariello, Christina A. Pacak, Louis M. Kunkel, Peter B. Kang
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 8, Pp 1302-1309 (2022)
Abstract Many individuals with muscular dystrophies remain genetically undiagnosed despite clinical diagnostic testing, including exome sequencing. Some may harbor previously undetected structural variants (SVs) or cryptic splice sites. We enrolled 1
Externí odkaz:
https://doaj.org/article/9c66bfaff84f41c59607be77930bfc87
Autor:
Marianela G. Dalghi, Wily G. Ruiz, Dennis R. Clayton, Nicolas Montalbetti, Stephanie L. Daugherty, Jonathan M. Beckel, Marcelo D. Carattino, Gerard Apodaca
Publikováno v:
JCI Insight, Vol 6, Iss 19 (2021)
The mechanisms that link visceral mechanosensation to the perception of internal organ status (i.e., interoception) remain elusive. In response to bladder filling, the urothelium releases ATP, which is hypothesized to stimulate voiding function by co
Externí odkaz:
https://doaj.org/article/8abfefc5202543cabde55b70bd38d134
Autor:
Stephanie L. Daugherty, Jonathan M. Beckel, Kyoungeun A. Kim, Bruce A. Freeman, Jiaxin Liu, Shaoyong Wang, William C. de Groat, Xiulin Zhang
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Activation of TRP channels expressed in urinary bladder afferent nerves and urothelium releases neurotransmitters that influence bladder function. Experiments were undertaken to examine the mechanisms underlying effects of TRPA1 (allyl isothiocyanate
Externí odkaz:
https://doaj.org/article/06b4a14dbd334bba8ae0608b28b63a92
Autor:
Alejandro Labastida-Ramírez, Eloísa Rubio-Beltrán, Kristian A. Haanes, René de Vries, Ruben Dammers, A. J. J. C. Bogers, Antoon van den Bogaerdt, Bruce L. Daugherty, Alexander H. J. Danser, Carlos M. Villalón, Antoinette MaassenVanDenBrink
Publikováno v:
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Racemic isometheptene [(RS)-isometheptene] is an antimigraine drug that due to its cardiovascular side-effects was separated into its enantiomers, (R)- and (S)-isometheptene. This study set out to characterize the contribution of
Externí odkaz:
https://doaj.org/article/3485624633554dbd81bf0de4dc2835b2