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P-053 Delayed presentations, increased complications, and worse outcomes after aneurysmal subarachnoid hemorrhage in the COVID-19 Era

Autor: Feras Akbik, Jonathan A Grossberg, Charles M Cawley, K. Martin, Ali Alawieh, C. Yang, Frank C. Tong, Daniel L. Barrow, R. Rindler, L. Danyluk, O. Sadan, Brian M. Howard, Owen Samuels

Publikováno v: Oral poster abstracts.

Introduction The COVID-19 pandemic has led to excess mortality out of proportion to documented COVID-19 cases while also affecting the care of non-COVID-19 related diseases. No data exist on the effects of the COVID-19 pandemic on the care and outcom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11f542fd0bc0e04bcf41bbd8bfe92c99
https://doi.org/10.1136/neurintsurg-2021-snis.89

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Immunomodulatory Activity of Synthetic Triterpenoids: Inhibition of Lymphocyte Proliferation, Cell-Mediated Cytotoxicity, and Cytokine Gene Expression Through Suppression of NF-κB

Autor: Andrew L. Danyluk, Yongbo Liu, Subhash C. Gautam, Scott A. Dulchavsky, Xiaohua Gao, Dorrah Deeb, Joseph Media

Publikováno v: Immunopharmacology and Immunotoxicology. 30:581-600

Synthetic oleanane triterpenoids (CDDO, CDDO-Im and CDDO-Me) are potent anti-inflammatory agents, but have not been investigated for effects on T cell-mediated immune responses. Here we demonstrate that CDDOs have profound immunosuppressive effects o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19fcc2a112a522059435fc8688c9e0f
https://doi.org/10.1080/08923970802135559

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Treatment with bone marrow-derived stromal cells accelerates wound healing in diabetic rats

Autor: Michael Chopp, David Kwon, Deborah S. Dulchavsky, Subhash C. Gautam, Andrew L. Danyluk, Kevin R. Mcintosh, Ali S. Arbab, Scott A. Dulchavsky, Mona Bansal, Xiaohua Gao, Yong Bo Liu

Publikováno v: International Wound Journal. 5:453-463

Bone marrow stem cells participate in tissue repair processes and may have a role in wound healing. Diabetes is characterised by delayed and poor wound healing. We investigated the potential of bone marrow-derived mesenchymal stromal cells (BMSCs) to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f6266c00cca2b4665937e46c592383
https://doi.org/10.1111/j.1742-481x.2007.00408.x

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Therapeutic Efficacy of Curcumin/TRAIL Combination Regimen for Hormone-Refractory Prostate Cancer

Autor: Dorrah Deeb, Tanja Andrzejewski, Subhash C. Gautam, Scott A. Dulchavsky, Ali S. Arbab, Andrew L. Danyluk, Xiaohua Gao

Publikováno v: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 17:257-267

Because of lack of effective treatment options for hormone-refractory prostate cancer at the present time, the need for developing novel therapeutic strategies and targets to treat and prevent the progression of hormone-sensitive prostate cancer to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621e3d102f355568ae89ff96803930c1
https://doi.org/10.3727/096504008786991611

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Curcumin [1,7-Bis(4-hydroxy-3-methoxyphenyl)-1–6-heptadine-3,5-dione; C21H20O6] Sensitizes Human Prostate Cancer Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand/Apo2L-Induced Apoptosis by Suppressing Nuclear Factor-κB via Inhibition of the Prosurvival Akt Signaling Pathway

Autor: Scott A. Dulchavsky, Shaza Al-Holou, Xiaohua Gao, Dorrah Deeb, Hao Jiang, Andrew L. Danyluk, Subhash C. Gautam

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 321:616-625

Our previous studies have shown that dietary pigment curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L)-induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::157fa16a8a25bfbab3e8ffb31c415224
https://doi.org/10.1124/jpet.106.117721

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Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway

Autor: Dorrah, Deeb, Hao, Jiang, Xiaohua, Gao, Shaza, Al-Holou, Andrew L, Danyluk, Scott A, Dulchavsky, Subhash C, Gautam

Publikováno v: The Journal of pharmacology and experimental therapeutics. 321(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9e685ddafcab3f2a2f5f3081902f474
https://pubmed.ncbi.nlm.nih.gov/17289836

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Self-Inflicted Blindness: Outline of a Rehabilitation Program

Autor: C.M. Tapper, R.C. Bland, L. Danyluk

Publikováno v: Canadian Journal of Occupational Therapy. 47:71-75

This paper describes a rehabilitation program carried out over sixteen months with a twenty-five year old male with schizophrenia and self-inflicted blindness. The overall goal of treatment was for the patient to acquire skills that would enable him

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a9e3b2fb0b5eb9c6ba15a257d9f1b87
https://doi.org/10.1177/000841748004700207

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Self-inflicted eye injuries and self-inflicted blindness

Autor: L. Danyluk, R.C. Bland, C.M. Tapper

Publikováno v: The Journal of nervous and mental disease. 167(5)

The case of a young man, suffering from schizophrenia, who injured his eyes with his hands and blinded himself, is described, along with his rehabilitation program. The classical and contemporary literature on self-inflicted blindness and self-inflic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cb02c607e9ea6b376d851b393c9018
https://pubmed.ncbi.nlm.nih.gov/448334

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