Zobrazeno 1 - 6
of 6
pro vyhledávání: '"L. Daniel Howell"'
Autor:
Xiu Bao Chang, John W. Hanrahan, Alexandra Evagelidis, John R. Riordan, Valerie Chappe, Deborah A. R. Hinkson, Jie Liao, L. Daniel Howell
Publikováno v:
Proceedings of the National Academy of Sciences. 101:390-395
Protein kinase C (PKC) phosphorylation stimulates the cystic fibrosis transmembrane conductance regulator (CFTR) channel and enhances its activation by protein kinase A (PKA) through mechanisms that remain poorly understood. We have examined the effe
Autor:
L. Daniel Howell
Americans are chronic shoe-wearers. We wear shoes almost constantly, certainly in public spaces, and often within the comfortable walls of our own homes. We need shoes. We need them for warmth and for protection. We wear shoes to be fashionable and b
Autor:
Jonathan A. Cohn, Andrew M. Kaz, Christoph Randak, Roy A. Borchardt, Jolanta Kole, L. Daniel Howell
Gating of the CFTR Cl− channel is associated with ATP hydrolysis at the nucleotide-binding domains (NBD1, NBD2) and requires PKA (protein kinase A) phosphorylation of the R domain. The manner in which the NBD1, NBD2 and R domains of CFTR (cystic fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa2779e9cad2712228e6ca1da838aa81
https://europepmc.org/articles/PMC1223935/
https://europepmc.org/articles/PMC1223935/
Publikováno v:
Biochemical and biophysical research communications. 271(2)
Residues 417–830 of the cystic fibrosis transmembrane conductance regulator (CFTR) were expressed as a glutathione- S -transferase fusion protein. This fusion protein, NBD1/R/GST, contains the regulatory and first nucleotide binding domains of CFTR
Publikováno v:
Gastroenterology. 120:A84-A84
Autor:
L. Daniel Howell, Jonathan A. Cohn, Christoph Randak, Yvette Mettey, Caroline Norez, Renaud Dérand, Laurence Bulteau-Pignoux, Michel Joffre, Frédéric Becq, Jean Michel Vierfond, Luis J. V. Galietta, Leila Romio, Olga Zegarra-Moran
Publikováno v:
Scopus-Elsevier
CIÊNCIAVITAE
CIÊNCIAVITAE
We have designed and synthesized benzo[c]quinolizinium derivatives and evaluated their effects on the activity of G551D cystic fibrosis transmembrane conductance regulator (CFTR) expressed in Chinese hamster ovary and Fisher rat thyroid cells. We dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e217a0f988e90b1b40955875dd962eb2
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035195682&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0035195682&partnerID=MN8TOARS