Zobrazeno 1 - 10
of 18
pro vyhledávání: '"L. D. Wallen"'
Autor:
Samuel Hawgood, V. K. M. Han, C. H. Lee, Joseph A. Kitterman, Cheryl J. Chapin, Lennell Allen, Leland G. Dobbs, L. D. Wallen, P. Joe
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 272:L95-L105
Previous fetal studies indicated that endocrine factors control surfactant maturation, whereas mechanical forces affect lung growth, but not surfactant. We altered mechanical forces in fetal sheep lungs at 100-108 days gestation by tracheal ligation
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 149:1005-1011
Aberrant pulmonary arterial flow has been associated with pulmonary hypoplasia, which is a common cause of death in newborns. The current experiments were designed to confirm whether interruption of postductal main pulmonary artery (MPA) flow causes
Publikováno v:
The Journal of endocrinology. 155(2)
A role for IGF binding proteins (IGFBPs) in lung development is suggested by the identification of IGFBPs in lung tissue and production of IGFBPs by fetal lung cells in culture. To characterize the expression of IGFBPs during lung development in the
Autor:
L. D. Wallen, Victor K. M. Han
Publikováno v:
The American journal of physiology. 267(5 Pt 1)
Insulin-like growth factors (IGF) I and II genes are expressed in developing lung tissue, but the details of distribution during different stages of lung development have not been delineated. To define the role of IGFs in lung development, the expres
Publikováno v:
Journal of developmental physiology. 16(3)
Pulmonary hypoplasia is increasing as a cause of neonatal death. To understand the pathophysiology of pulmonary hypoplasia, the physiology of fetal lung growth must first be understood. Lung fluid production and fetal breathing are primary factors re
Autor:
Joseph A. Kitterman, C.-C. H. Lee, Ronald I. Clyman, Françoise Mauray, Renate D. Savich, F. A. Guerra, L. D. Wallen
Publikováno v:
Journal of Applied Physiology. 64:2160-2166
To test the hypothesis that prostaglandin (PG) E2 is a respiratory depressant in the newborn lamb, 12 chronically catheterized, unanesthetized lambs (age 2–6 days) were infused with progressively increasing doses of PGE2 (0.1, 0.5, 1.0, and 5.0 mic
Autor:
D. T. Murai, C.-C. H. Lee, Françoise Mauray, Ronald I. Clyman, Joseph A. Kitterman, L. D. Wallen
Publikováno v:
Journal of Applied Physiology. 64:759-766
There is evidence that prostaglandins (PG), specifically PGE2, participate in the regulation of fetal breathing movements (FBM). During late gestation, when FBM occur intermittently and primarily during low-voltage electrocortical activity, the conce
Autor:
D. T. Murai, Joseph A. Kitterman, C.-C. H. Lee, Ronald I. Clyman, L. D. Wallen, Françoise Mauray
Publikováno v:
Journal of Applied Physiology. 60:526-531
In fetal sheep, plasma prostaglandin (PG) E2 concentrations are high, and fetal breathing movements (FBM) occur intermittently, primarily during low-voltage fast electrocortical activity (LVFA). There is evidence suggesting that prostaglandins, speci
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 59(2)
The role of the peripheral chemoreceptors in the control of fetal breathing movements has not been fully defined. To determine whether denervation of the peripheral chemoreceptors affects fetal breathing movements, we studied 14 chronically catheteri
Publikováno v:
Journal of developmental physiology. 12(2)
Prostaglandins may be involved in some aspects of fetal lung development, including surfactant metabolism, tracheal fluid production, and possibly lung growth. In the fetus, during the days before delivery, plasma PGE2 concentration increases and con