Zobrazeno 1 - 10
of 160
pro vyhledávání: '"L. D. Luk'yanova"'
Autor:
Natalia V. Belosludtseva, Alexey A Mosentsov, L. L. Pavlik, E. L. Germanova, L. D. Luk'yanova, Natalya V. Khmil, Yulia I. Kirova, Galina D. Mironova
Publikováno v:
Journal of Bioenergetics and Biomembranes. 51:329-340
The mitochondrial structure and the contents of subunits (NDUFV2, SDHA, Cyt b, COX1) of mitochondrial respiratory complexes I-IV as well as of the hypoxia-inducible factor (HIF-1α) in the brain cortex (BC) of rats with high resistance (HR) and low r
Publikováno v:
Bulletin of Experimental Biology and Medicine. 166:426-431
We performed a complex study of the dependence of immediate reaction of catalytic subunits in mitochondrial enzymes (NDUFV2, SDHA, Cyt b, COX1, and ATP5A) in rat cerebral cortex (the most hypoxia-sensitive tissue) on the severity and duration of hypo
Publikováno v:
Bulletin of Experimental Biology and Medicine. 164:298-303
Hypoxia-induced immediate expression of transcription factor HIF-1α in the brain cortex is regulated by succinate produced in both the tricarbonic acid cycle and GABA shunt reactions and is induced by succinate-containing drugs. These facts prove th
Autor:
I. B. Mikheeva, L. D. Luk'yanova, L. L. Pavlik, Yu. I. Kirova, V. P. Berest, E. L. Germanova, Galina D. Mironova, Ya. M. Al’-Mugkhrabi
Publikováno v:
Bulletin of Experimental Biology and Medicine. 164:376-381
We performed ultrastructural study of cerebral cortex mitochondria in rats with different tolerance to oxygen deficiency (low resistant and highly resistant specimens). Low resistant rats were characterized by the prevalence of mitochondria with ligh
Autor:
Natalya V. Khmil, Galina D. Mironova, L. D. Luk'yanova, E. L. Germanova, M. I. Shigaeva, Lybov Pavlik, I. B. Mikheeva
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8636, p 8636 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences
Volume 22
Issue 16
This study was the first comprehensive investigation of the dependence of mitochondrial enzyme response (catalytic subunits of mitochondrial complexes (MC) I-V, including NDUFV2, SDHA, Cyt b, COX1 and ATP5A) and mitochondrial ultrastructure in the ra
Publikováno v:
Bulletin of Experimental Biology and Medicine. 155:767-770
Extralife, a Pentaphylloides fruticos extract, in concentrations of 0.005-10 μg/ml dose-dependently increased H2O2 production in rat heart mitochondria in the presence of respiration substrates. Extralife decreased ATP-induced accumulation of H2O2 r
Autor:
Yu. I. Kirova, L. D. Luk'yanova
Publikováno v:
Bulletin of Experimental Biology and Medicine. 151:292-296
We studied the effect of single hypoxic preconditioning exposure (hypobaric hypoxia, 5000 m, 60 min) on free radical processes, glutathione system, and antioxidant defense enzymes in tissues of rats with different resistance to acute hypoxia. The int
Publikováno v:
Bulletin of Experimental Biology and Medicine. 150:685-689
Different modes of hypoxic exposure led to phasic changes in activities of the complement system components in rats sensitive to hypoxia starting from the first minutes of the posthypoxic period and persisting for 24 h and longer. The direction of sh
Publikováno v:
Bulletin of Experimental Biology and Medicine. 148:587-591
Succinate-containing derivatives of 3-hydroxypyridine, mexidol and proxypin, serve as succinate donors for the respiratory chain and contribute to activation of the succinate oxidase pathway of oxidation. Under conditions of hypoxia, these changes pr
Publikováno v:
Bulletin of Experimental Biology and Medicine. 147:400-404
Single exposure to moderate (10% O(2)) hypobaric, normobaric, and intermittent hypoxia is followed by a preconditioning response of the organism. The mechanisms for immediate adaptation are activated during the hypoxic period. Intermittent reoxygenat