Comprehensive Map of the Regulated Cell Death Signaling Network: A Powerful Analytical Tool for Studying Diseases

Autor: Emmanuel Barillot, Boris Zhivotovsky, L. Cristobal Monraz Gomez, Jean-Marie Ravel, Nicolas Sompairac, Guido Kroemer, Inna Kuperstein, Laurence Calzone, Andrei Zinovyev

Publikováno v: Cancers
Cancers, 2020, 12 (4), pp.990. ⟨10.3390/cancers12040990⟩
Cancers, MDPI, 2020, 12 (4), pp.990. ⟨10.3390/cancers12040990⟩
Volume 12
Issue 4
Cancers, Vol 12, Iss 990, p 990 (2020)

The processes leading to, or avoiding cell death are widely studied, because of their frequent perturbation in various diseases. Cell death occurs in three highly interconnected steps: Initiation, signaling and execution. We used a systems biology ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3f90b12ecb05af80a057e83c3a41c2
https://inria.hal.science/hal-03168365/document

Application of Atlas of Cancer Signalling Network in preclinical studies

Autor: Inna Kuperstein, Maria Kondratova, Emmanuel Barillot, Andrei Zinovyev, Jean-Marie Ravel, L. Cristobal Monraz Gomez

Publikováno v: Briefings in bioinformatics. 20(2)

Cancer initiation and progression are associated with multiple molecular mechanisms. The knowledge of these mechanisms is expanding and should be converted into guidelines for tackling the disease. Here, we discuss the formalization of biological kno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b203e8b7448b5977a2ef581d1793f638
https://pubmed.ncbi.nlm.nih.gov/29726961