Zobrazeno 1 - 10
of 16
pro vyhledávání: '"L. Cristina Gavrilescu"'
Autor:
Stuart W. Hicks, Katharine C. Lai, L. Cristina Gavrilescu, Yong Yi, Surina Sikka, Prerak Shah, Meghan E. Kelly, Jenny Lee, Leanne Lanieri, Jose F. Ponte, Callum M. Sloss, Angela Romanelli
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 9, Pp 661-671 (2017)
Naratuximab emtansine (IMGN529) is an investigational antibody-drug conjugate consisting of a CD37-targeting antibody conjugated to the maytansine-derived microtuble disruptor, DM1. IMGN529 has shown promising preclinical and clinical activity in non
Externí odkaz:
https://doaj.org/article/7f5d54c2865f4fee8b837a40cbdf54db
Autor:
Jose F. Ponte, Katharine C. Lai, Meghan E. Kelly, Angela Romanelli, Surina Sikka, Callum M. Sloss, Stuart W. Hicks, L. Cristina Gavrilescu, Prerak Shah, Jenny Lee, Yong Yi, Leanne Lanieri
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 9, Pp 661-671 (2017)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Naratuximab emtansine (IMGN529) is an investigational antibody-drug conjugate consisting of a CD37-targeting antibody conjugated to the maytansine-derived microtuble disruptor, DM1. IMGN529 has shown promising preclinical and clinical activity in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc65cee4813d48eb4185e60444cd9099
https://doi.org/10.1016/j.neo.2017.06.001
https://doi.org/10.1016/j.neo.2017.06.001
Autor:
Jan Pinkas, Ling Dong, Yulius Setiady, Luke Harris, Sharon Chicklas, L. Cristina Gavrilescu, Richard Gregory, Joe Ponte
Publikováno v:
Cancer Immunology Research. 8:B21-B21
Background: Immune checkpoint blockade, specifically targeting PD-1/PD-L1, is a promising approach for cancer therapy. However, for some common cancers, such as epithelial ovarian cancer (EOC), PD1/PDL1 blockade as monotherapy has a low response rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b56c37782c31f5b98ee519fa33cafd1
https://doi.org/10.1158/2326-6074.tumimm18-b21
https://doi.org/10.1158/2326-6074.tumimm18-b21
Autor:
Jessica Flechtner, Paul J. Giannasca, L. Cristina Gavrilescu, Mojca Skoberne, Scott Munzer, Richard Malley, Bharat Dixit, Kristin Moffitt, Angela Howard, Todd Gierahn
Publikováno v:
Infection and Immunity. 82:2079-2086
Infections with Streptococcus pneumoniae cause substantial morbidity and mortality, particularly in children in developing nations. Polysaccharide-conjugate vaccines provide protection against both invasive disease and colonization, but their use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::539708055a9acdf767cc612a6d6718a3
https://doi.org/10.1128/iai.01632-13
https://doi.org/10.1128/iai.01632-13
Autor:
Kathryn Selvitelli, Steven Boule, Kerry Donahue, L. Cristina Gavrilescu, Katharine C. Lai, Stuart W. Hicks, Min Li, Surina Sikka
Publikováno v:
Cancer Research. 79:4817-4817
With cancer among the leading causes of death worldwide, the search for better, personalized treatments is imperative. Novel techniques such as next generation sequencing have identified many assayable genetic biomarkers associated with cancer in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97576ac5f2ebbd269c14c77632584f8e
https://doi.org/10.1158/1538-7445.am2019-4817
https://doi.org/10.1158/1538-7445.am2019-4817
Autor:
Hans G. Klingemann, Yi Fen Lu, Monica Betancur, Richard A. Van Etten, L. Cristina Gavrilescu, Katherine Lazarides
Publikováno v:
Blood. 119:273-284
Among hematologic neoplasms, chronic myeloid leukemia (CML) is exquisitely sensitive to graft-versus-leukemia (GVL) because patients relapsing after allogeneic hematopoietic stem-cell transplantation (alloHSCT) can be cured by donor leukocyte infusio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc4dfbbb4685a0a9052403854543900
https://doi.org/10.1182/blood-2011-01-331009
https://doi.org/10.1182/blood-2011-01-331009
Publikováno v:
Infection and Immunity. 71:6109-6115
Apoptosis, or programmed cell death (PCD), is a physiological response that eliminates unwanted cells, an evolutionarily ancient process that is present in all multicellular organisms. Apoptosis is used during embryogenesis as a way to shape future a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea4cc73d65f657b149dcfba81da57e8
https://doi.org/10.1128/iai.71.11.6109-6115.2003
https://doi.org/10.1128/iai.71.11.6109-6115.2003
Publikováno v:
Infection and Immunity. 69:4898-4905
The immunomodulatory role of neutrophils during infection withToxoplasma gondiiwas investigated. Monoclonal antibody-mediated depletion revealed that neutrophils are essential for survival during the first few days of infection. Moreover, neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6abcea60aed65c89397b3bdd239358
https://doi.org/10.1128/iai.69.8.4898-4905.2001
https://doi.org/10.1128/iai.69.8.4898-4905.2001
Publikováno v:
Current Protocols in Pharmacology
Human myeloproliferative diseases are common hematologic disorders characterized by clonal overproduction of maturing myeloid or erythroid cells, often caused by expression of a mutant, dysregulated tyrosine kinase (TK). These diseases can be accurat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b90e08d6249fc8fb1eee9bd0c4890b
https://pubmed.ncbi.nlm.nih.gov/22294220
https://pubmed.ncbi.nlm.nih.gov/22294220
Autor:
Jian Zhong, L. Cristina Gavrilescu, Stephen Garafalo, Lauren Murray, John H. Kehrl, Richard A. Van Etten, John M. Kyriakis, Amy Simon, Arpad Molnar
Systemic inflammation arising from the organismal distribution of pathogen-associated molecular patterns is a major cause of clinical morbidity and mortality. Herein we report a critical and previously unrecognized in vivo role for germinal center ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ad9f6561df13137d789fc90e2fce24
https://europepmc.org/articles/PMC2657458/
https://europepmc.org/articles/PMC2657458/
