Oral absorption of oxycodone in patients with short bowel syndrome

Autor: Lars Vinter-Jensen, Lona L. Christrup, Louise Ladebo, Henrik Rasmussen, Asbjørn Mohr Drewes, Johanne Hestvang, Anne Estrup Olesen, Maja Schjønning Mikkelsen

Publikováno v: Ladebo, L, Vinter-Jensen, L, Hestvang, J, Mikkelsen, M S, Rasmussen, H H, Christrup, L L, Drewes, A M & Olesen, A E 2021, ' Oral absorption of oxycodone in patients with short bowel syndrome ', Scandinavian Journal of Gastroenterology, vol. 56, no. 9, pp. 1023-1029 . https://doi.org/10.1080/00365521.2021.1944299

BACKGROUND: Short bowel syndrome is a disorder with several complications such as malnutrition and failure of drug therapy. Treatment with opioids is needed in many patients, and oral medication is preferred. However, optimal dosing is a difficult ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4d945dcbdfe0365d2fdbb35cd971e2
https://doi.org/10.1080/00365521.2021.1944299

Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone

Autor: Asbjørn Mohr Drewes, Grzegorz J. Pacyk, Jens Peter Kroustrup, Kenneth T. Kongstad, David J. R. Foster, Ahmad Y. Abuhelwa, Lona L. Christrup, Louise Ladebo, Anne Estrup Olesen

Publikováno v: Ladebo, L, Abuhelwa, A Y, Foster, D J R, Kroustrup, J P, Pacyk, G J, Kongstad, K T, Drewes, A M, Christrup, L L & Olesen, A E 2021, ' Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone ', Basic & Clinical Pharmacology & Toxicology, vol. 129, no. 3, pp. 232-245 . https://doi.org/10.1111/bcpt.13634

The physiological changes following Roux-en-Y gastric bypass (RYGB) surgery may impact drug release from mechanistically different controlled-release tablets, making generic substitution inappropriate. This study aimed to characterise the pharmacokin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b934d490e6e88500dc8fb6a9d66a46
https://hdl.handle.net/11541.2/148124

Chronic abdominal pain and persistent opioid use after bariatric surgery

Autor: Amalie Højmose Simoni, Lona L. Christrup, Louise Ladebo, Søren Paaske Johnsen, Asbjørn Mohr Drewes, Anne Estrup Olesen

Publikováno v: Simoni, A H, Ladebo, L, Christrup, L L, Drewes, A M, Johnsen, S P & Olesen, A E 2020, ' Chronic abdominal pain and persistent opioid use after bariatric surgery ', Scandinavian Journal of Pain, vol. 20, no. 2, pp. 239–251 . https://doi.org/10.1515/sjpain-2019-0092
Simoni, A H, Ladebo, L, Christrup, L L, Drewes, A M, Johnsen, S P & Olesen, A E 2020, ' Chronic abdominal pain and persistent opioid use after bariatric surgery ', Scandinavian Journal of Pain, vol. 20, no. 2, pp. 239-251 . https://doi.org/10.1515/sjpain-2019-0092

Background and aims Bariatric surgery remains a mainstay for treatment of morbid obesity. However, long-term adverse outcomes include chronic abdominal pain and persistent opioid use. The aim of this review was to assess the existing data on prevalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d3ed6a1318fa3501c5073806e5ed7a
https://vbn.aau.dk/ws/files/399417009/_18778879_Scandinavian_Journal_of_Pain_Chronic_abdominal_pain_and_persistent_opioid_use_after_bariatric_surgery.pdf

Offset Analgesia and The Impact of Treatment with Oxycodone and Venlafaxine: A Placebo-Controlled, Randomized Trial in Healthy Volunteers

Autor: Anne Estrup Olesen, Asbjørn Mohr Drewes, Dina Lelic, Thomas Dahl Nissen, Matias Nilsson, Christina Brock, Lona L. Christrup

Publikováno v: Olesen, A E, Nissen, T D, Nilsson, M, Lelic, D, Brock, C, Christrup, L L & Drewes, A M 2018, ' Offset Analgesia and The Impact of Treatment with Oxycodone and Venlafaxine : A Placebo-Controlled, Randomized Trial in Healthy Volunteers ', Basic and Clinical Pharmacology and Toxicology, vol. 123, no. 6, pp. 727-731 . https://doi.org/10.1111/bcpt.13078

Offset analgesia (OA) is a pain-modulating mechanism described as a disproportionately large decrease in pain intensity evoked by a discrete decrease in stimulus temperature. The role of the opioidergic, serotonergic and noradrenergic systems on OA r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdc09d44206186c919a4cbf89feb27d
https://doi.org/10.1111/bcpt.13078

Recreational drug use at a major music festival: trend analysis of anonymised pooled urine

Autor: Mette Findal Andreasen, Lotte C. G. Hoegberg, Dan Staerk, Jesper Soe, Kenneth T. Kongstad, Cecilie Deleuran Christiansen, Lona L. Christrup, Rasmus Telving

Publikováno v: Hoegberg, L C G, Christiansen, C, Soe, J, Telving, R, Andreasen, M F, Staerk, D, Christrup, L L & Kongstad, K T 2018, ' Recreational drug use at a major music festival: trend analysis of anonymised pooled urine ', Clinical Toxicology, vol. 56, no. 4, pp. 245-255 . https://doi.org/10.1080/15563650.2017.1360496

Objective: The spread of new psychoactive substances (NPS) has expanded rapidly in the last decade. The complexity of the pharmacological effects of NPS challenges the traditional treatment guidelines, and information of the emergence of new arrivals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db078ea99cfd8c20283315b75c93332
https://doi.org/10.1080/15563650.2017.1360496