Zobrazeno 1 - 10
of 247
pro vyhledávání: '"L. Charlotte"'
Autor:
Anniek Strijdhorst, L. Charlotte J. de Bree, Reinout van Crevel, Hanna K. de Jong, Sabine M. Hermans
Publikováno v:
Clinical Infection in Practice, Vol 22, Iss , Pp 100354- (2024)
We describe the case of a 70-year-old immunocompromised patient who developed a severe disseminated Mycobacterium bovis BCG infection with several infected prosthetic joints and soft tissue abscesses following intravesical BCG instillation for bladde
Externí odkaz:
https://doaj.org/article/6dc10a3dcdfc42638af3a3f47b6fbeca
Autor:
Anaísa V. Ferreira, Sarantos Kostidis, Laszlo A. Groh, Valerie A.C.M. Koeken, Mariolina Bruno, Ilayda Baydemir, Gizem Kilic, Özlem Bulut, Theano Andriopoulou, Victoria Spanou, Kalliopi D. Synodinou, Theologia Gkavogianni, Simone J.C.F.M. Moorlag, L. Charlotte de Bree, Vera P. Mourits, Vasiliki Matzaraki, Werner J.H. Koopman, Frank L. van de Veerdonk, Georgios Renieris, Martin Giera, Evangelos J. Giamarellos-Bourboulis, Boris Novakovic, Jorge Domínguez-Andrés
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112658- (2023)
Summary: Itaconate is an immunomodulatory metabolite produced by immune cells under microbial stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti-inflammatory responses. We show that dimethyl itaconate, a derivative
Externí odkaz:
https://doaj.org/article/6e7649ccdf4846afb0796f373689a5d6
Autor:
Wenchao Li, Simone J.C.F.M. Moorlag, Valerie A.C.M. Koeken, Rutger J. Röring, L. Charlotte J. de Bree, Vera P. Mourits, Manoj K. Gupta, Bowen Zhang, Jianbo Fu, Zhenhua Zhang, Inge Grondman, Krista E. van Meijgaarden, Liang Zhou, Ahmed Alaswad, Leo A.B. Joosten, Reinout van Crevel, Cheng-Jian Xu, Mihai G. Netea, Yang Li
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112487- (2023)
Summary: Bacillus Calmette-Guérin (BCG) vaccination is a prototype model for the study of trained immunity (TI) in humans, and results in a more effective response of innate immune cells upon stimulation with heterologous stimuli. Here, we investiga
Externí odkaz:
https://doaj.org/article/eb1c8ea632d74699ab8d95c27ce700ab
Autor:
Joshua Gillard, Bastiaan A. Blok, Daniel R. Garza, Prashanna Balaji Venkatasubramanian, Elles Simonetti, Marc J. Eleveld, Guy A. M. Berbers, Pieter G. M. van Gageldonk, Irma Joosten, Ronald de Groot, L. Charlotte J. de Bree, Reinout van Crevel, Marien I. de Jonge, Martijn A. Huynen, Mihai G. Netea, Dimitri A. Diavatopoulos
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Acellular pertussis (aP) booster vaccines are central to pertussis immunization programs, although their effectiveness varies. The Bacille Calmette-Guérin (BCG) vaccine is a prototype inducer of trained immunity, which enhances immune respo
Externí odkaz:
https://doaj.org/article/03fd26af521743d3bf22ca86c1c84e94
Autor:
Martin Stražar, Vera P. Mourits, Valerie A. C. M. Koeken, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Leo A. B. Joosten, Reinout van Crevel, Hera Vlamakis, Mihai G. Netea, Ramnik J. Xavier
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background The bacillus Calmette-Guérin (BCG) vaccine protects against tuberculosis and heterologous infections but elicits high inter-individual variation in specific and nonspecific, or trained, immune responses. While the gut microbiome
Externí odkaz:
https://doaj.org/article/55e912bb35d948619f632bcf4e2b1b3d
Autor:
Yunus Kuijpers, Xiaojing Chu, Martin Jaeger, Simone J. C. F. M. Moorlag, Valerie A. C. M. Koeken, Bowen Zhang, Aline de Nooijer, Inge Grondman, Manoj Kumar Gupta, Nico Janssen, Vera P. Mourits, L. Charlotte J. de Bree, Quirijn de Mast, Frank L. van de Veerdonk, Leo A. B. Joosten, Yang Li, Mihai G. Netea, Cheng-Jian Xu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Recent genome-wide association studies (GWASs) of COVID-19 patients of European ancestry have identified genetic loci significantly associated with disease severity. Here, we employed the detailed clinical, immunological and multi-omics dataset of th
Externí odkaz:
https://doaj.org/article/0b35664509264d24882986c6d51eaca4
Autor:
Jona Walk, L. Charlotte J. de Bree, Wouter Graumans, Rianne Stoter, Geert-Jan van Gemert, Marga van de Vegte-Bolmer, Karina Teelen, Cornelus C. Hermsen, Rob J. W. Arts, Marije C. Behet, Farid Keramati, Simone J. C. F. M. Moorlag, Annie S. P. Yang, Reinout van Crevel, Peter Aaby, Quirijn de Mast, André J. A. M. van der Ven, Christine Stabell Benn, Mihai G. Netea, Robert W. Sauerwein
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Immune activation induces long-term alterations of setpoints, impacting responses to subsequent unrelated stimuli. Here the authors show that volunteers vaccinated with BCG respond to controlled human malaria infection with increased clinical symptom
Externí odkaz:
https://doaj.org/article/548440850a244fa5947c578ae0771c61
Autor:
Jorge Domínguez-Andrés, Rob J.W. Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A. Blok, L. Charlotte J. de Bree, Mariolina Bruno, Özlem Bulut, Priya A. Debisarun, Helga Dijkstra, Jéssica Cristina dos Santos, Anaísa V. Ferreira, Daniela Flores-Gomez, Laszlo A. Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A.C.M. Koeken, Heidi Lemmers, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jelmer H. van Puffelen, Katrin Rabold, Rutger J. Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P. Riksen, Leo A.B. Joosten, Mihai G. Netea
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100365- (2021)
Summary: A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline he
Externí odkaz:
https://doaj.org/article/e0ee4ea53a9e4be785098507068f1cd9
Autor:
Jona Walk, Farid Keramati, L. Charlotte J. de Bree, Rob J. W. Arts, Bas Blok, Mihai G. Netea, Hendrik G. Stunnenberg, Robert W. Sauerwein
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Innate immune memory responses (also termed “trained immunity”) have been described in monocytes after BCG vaccination and after stimulation in vitro with microbial and endogenous ligands such as LPS, β-glucan, oxidized LDL, and monosodium urate
Externí odkaz:
https://doaj.org/article/ddcae7fd4b7542da9b9a7fbeae4f466b
Autor:
Simone J.C.F.M. Moorlag, Yessica Alina Rodriguez-Rosales, Joshua Gillard, Stephanie Fanucchi, Kate Theunissen, Boris Novakovic, Cynthia M. de Bont, Yutaka Negishi, Ezio T. Fok, Lydia Kalafati, Panayotis Verginis, Vera P. Mourits, Valerie A.C.M. Koeken, L. Charlotte J. de Bree, Ger J.M. Pruijn, Craig Fenwick, Reinout van Crevel, Leo A.B. Joosten, Irma Joosten, Hans Koenen, Musa M. Mhlanga, Dimitri A. Diavatopoulos, Triantafyllos Chavakis, Mihai G. Netea
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108387- (2020)
Summary: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) protects against some heterologous infections, probably via induction of non-specific innate immune memory in monocytes and natural killer (NK) cells, a process known as trained immuni
Externí odkaz:
https://doaj.org/article/867252fa4e9041d0b4262603d849461e