Zobrazeno 1 - 10
of 122
pro vyhledávání: '"L. Camón"'
Publikováno v:
Journal of Neuroscience Research. 66:1101-1111
Department of Neurochemistry, Institut d’Investigacions Biome`diques de Barcelona, Consejo Superior deInvestigaciones Cienti´ficas-Institut d’Investigacions Biome`diques August Pi i Sunyer, Barcelona, SpainPutrescine (PUT) increases have been s
Publikováno v:
Neuroscience Letters. 217:1-4
The motor responses (such as stereotypic behavior or convulsions) induced in rats by N-methyl- d -aspartate (NMDA) administered systemically were followed by a rapid, moderate increase in the putrescine concentration in plasma which preceded an incre
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Dopamine (DA) released by substantia nigra pars compacta (SNc) neurons is a key regulator of motor activity. A deficiency in the striatum DA content due to SNc degeneration is a characteristic of Parkinson's disease. The involvement of excitotoxic me
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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We examined the effects of the local infusion of kainic acid (KA), by reverse dialysis in the rat striatum, on the concentration of polyamines in the extracellular striatal compartment and in tissue. KA infusion markedly increased (3-fold) extracellu
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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We study the brain regional distribution of putrescine after excitotoxic damage. After status epilepticus induced by kainic acid (9 mg/kg, i.p.) we found an increase of putrescine in all the regions analyzed. Three kind of regions can be identified a
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The distribution of polyamines in the human basal ganglia was examined, using dansyl-derivatives and high pressure liquid chromatography with fluorimetric detection. A heterogeneous distribution of putrescine, spermidine (SD) and spermine (SM) was ob
Publikováno v:
Journal of neuroscience research. 51(3)
While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role of metabotropic glutamate receptors (mGluRs) in epileptogenesis and neuronal injury. Intrac
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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While it is well documented that the overactivation of ionotropic glutamate receptors leads to seizures and excitotoxic injury, little is known about the role of metabotropic glutamate receptors (mGluRs) in epileptogenesis and neuronal injury. Intrac
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Putrescine has been suggested to have an inhibitory effect on the excitability of the central nervous system. In the present study we found that 2 and 3 weeks after status epilepticus induced by kainic acid, rats had increased concentrations of putre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d825b6b9b3405cfc17adb0282572c8
http://hdl.handle.net/10261/268830
http://hdl.handle.net/10261/268830
Publikováno v:
Amino Acids 12: 1-7 (1997).
The cerebral ODC/polyamine system is disturbed by brain injury. The main modifications are important increases in ODC activity and putrescine concentration, with minor variations in spermidine and spermine concentrations. A great diversity of stimuli