Výsledky vyhledávání - "L. C. Wilkes"

Effect of gastrin-releasing peptide on the secretion of mouse islet hormones in vitro

Autor: J. M. Conlon, Keith D. Buchanan, M. G. Thompson, C. J. Bailey, L. C. Wilkes

Publikováno v: Scopus-Elsevier

Collagenase-isolated mouse islets were incubated with gastrin-releasing peptide (GRP). At 5·6 mmol glucose/1, 10 nmol GRP/l increased the release of insulin (by 50%) and glucagon (by twofold), decreased the release of pancreatic polypeptide (by 35%)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8333914c52a93097ecb37d470326b4
https://doi.org/10.1677/joe.0.1270335

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Characterization of the endothelin binding site on bovine adrenomedullary chromaffin cells: comparison with vascular smooth muscle cells. Evidence for receptor heterogeneity

Autor: L C, Wilkes, M R, Boarder

Publikováno v: The Journal of pharmacology and experimental therapeutics. 256(2)

Specific binding sites for synthetic endothelin (ET) isoforms, ET-1 and ET-3 were studied in a bovine adrenomedullary chromaffin cell-rich preparation, and compared to those on A10 cells, a vascular smooth muscle cell line. Both [125I]ET-1 and [125I]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::38964a95f324f944539f1d86386b1564
https://pubmed.ncbi.nlm.nih.gov/1847205

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Effects of gastric inhibitory polypeptide, vasoactive intestinal polypeptide and peptide histidine isoleucine on the secretion of hormones by isolated mouse pancreatic islets

Autor: C. J. Bailey, Keith D. Buchanan, P. H. Armstrong, L. C. Wilkes, J. M. Conlon

Publikováno v: Scopus-Elsevier

The release of insulin, glucagon, somatostatin and pancreatic polypeptide (PP) by isolated mouse pancreatic islets was determined during 30-min incubations at 5.6 and 16.7 mmol glucose/l in the absence and presence of gastric inhibitory polypeptide (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5535285e6537e3a09033a9b5c8301f0e
https://pubmed.ncbi.nlm.nih.gov/1973701

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Effects of growth hormone-releasing hormone on the secretion of islet hormones and on glucose homeostasis in lean and genetically obese-diabetic (ob/ob) mice and normal rats

Autor: Keith D. Buchanan, L. C. Wilkes, J. M. Conlon, Peter R. Flatt, C. J. Bailey

Publikováno v: Journal of Endocrinology. 123:19-24

The effect of synthetic human growth hormone-releasing hormone(1–40) (hGHRH-40) on the function of the endocrine pancreas and on glucose homeostasis in lean and genetically obese-diabetic (ob/ob) mice and normal rats has been examined. The addition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6851585b62e98cc03a095f5328a873f9
https://doi.org/10.1677/joe.0.1230019

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