Zobrazeno 1 - 10
of 117
pro vyhledávání: '"L. C. Iorio"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(1)
The present study investigated whether blockade of conditioned avoidance responding (CAR) in rats by selective D1 and D2 receptor antagonists could be differentially affected by anticholinergics. The results show that atropine and scopolamine dose-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ba79b314704ab740ade3974894f2b15
https://pubmed.ncbi.nlm.nih.gov/1830098
https://pubmed.ncbi.nlm.nih.gov/1830098
Pharmacological evaluation of SCH-12679: evidence for an in vivo antagonism of D1-dopamine receptors
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 252(2)
The benzazepine compound SCH-12679 has been shown to have clinical efficacy against aggressive behavior in mentally deficient patients. The purpose of the present investigation was to evaluate the potential mechanism of action of SCH-12679. Because o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::833f1f5a320d4addd9eb42433916afa6
https://pubmed.ncbi.nlm.nih.gov/1968972
https://pubmed.ncbi.nlm.nih.gov/1968972
Publikováno v:
Agents and Actions. 14:590-597
SCH 29851 [8-chloro[6,11-dihydro-11-(1-carboethoxy-4-piperidylidene)- 5-H-benzo [5,6]cyclohepta[1,2-b]-pyridine] was discovered as part of a search for a new antihistamine without effects on the central nervous system (CHS). Antihistaminic potency an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8daaff1153c37f5943d8936dc7f254bb
https://doi.org/10.1007/bf01978891
https://doi.org/10.1007/bf01978891
Publikováno v:
Journal of Pharmacy and Pharmacology. 20:368-372
N 6,2′-O-Dibutyryl 3′,5′-cyclic adenosine monophosphate (dibutyryl 3′,5′-amp), isoprenaline and theophylline relax the guinea-pig tracheal chain preparation; whereas 3′,5′-cyclic adenosine monophosphate (3′,5′-amp) does not. The rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a6bb0597b7f04850cd24244d31225e
https://doi.org/10.1111/j.2042-7158.1968.tb09761.x
https://doi.org/10.1111/j.2042-7158.1968.tb09761.x
Autor:
J. H. Trapold, Nicholas Paolella, L. C. Iorio, George Leslie, John H. Gogerty, Clarence Hoffman, Galantay Eugene E
Publikováno v:
Journal of Medicinal Chemistry. 12:444-449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698e4e29151366d248ef9a316fad5400
https://doi.org/10.1021/jm00303a025
https://doi.org/10.1021/jm00303a025
Publikováno v:
Journal of Medicinal Chemistry. 19:436-438
A series of aryl bicyclic analogs of succinimide and glutarimide was prepared and evaluated for CNS depressant activity. The 8a-aryl-3,4,6,7,8,8a-hexahydro-2H-pyrrolo[2,1-beta][1,3]oxazin-6-ones possessed the best overall spectrum of activity relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef6f909e1a43c333312fcf6259f5cba
https://doi.org/10.1021/jm00225a023
https://doi.org/10.1021/jm00225a023
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 213(3)
The antinociceptive effects of the non-narcotic analgesics clonixin, flunixin, acetylsalicylic acid, aminopyrine and phenylbutazone in the yeast paw test were blocked by l-lysine. Blockade occurred at doses of l-lysine which did not affect pain thres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dfa595f921957f2a39ee1a4d1f71ead
https://pubmed.ncbi.nlm.nih.gov/6782234
https://pubmed.ncbi.nlm.nih.gov/6782234
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 226(2)
SCH 23390 [R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepine-7-ol) possesses pharmacologic effects similar to standard antipsychotics, including selective supression of conditioned avoidance responding in rats and squirrel monkeys,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e916812c4e970029cfdef836bf5a774
https://pubmed.ncbi.nlm.nih.gov/6135795
https://pubmed.ncbi.nlm.nih.gov/6135795
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 245(3)
SCH 34826 [(S)-N-[N-[1-[[(2,2-dimethyl-1,3-dioxolan-4yl) methoxy]carbonyl]-2-phenylethyl]-L-phenylalanine]-beta-alanine] was synthesized as a p.o. active prodrug enkephalinase inhibitor. In vivo, it is de-esterified to SCH 32615 (N-[L-(-1-carboxy-2-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c587c5717d616f3bc297956697be30d
https://pubmed.ncbi.nlm.nih.gov/3164388
https://pubmed.ncbi.nlm.nih.gov/3164388
Autor:
Max Denzer, L. C. Iorio, R. J. Strohschein, G. Corriveau, Galantay Eugene E, R. Simpson, Ryan Ea, Douglas C. Knorr, N. A. Paodella, John H. Gogerty, Y. Uike
Publikováno v:
Chemischer Informationsdienst. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e33ec01e30c2d3e7df696798d810fd7b
https://doi.org/10.1002/chin.197515250
https://doi.org/10.1002/chin.197515250