Zobrazeno 1 - 10
of 20
pro vyhledávání: '"L. C. Happerfield"'
Publikováno v:
The Journal of Pathology. 183:412-417
Insulin-like growth factors (IGFs) play an important role in normal cellular growth and development and have been implicated in the regulation of tumour growth. Two receptors are recognized, IGFR-1 and IGFR-2, of which one, IGFR-1, is a transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bc925288e2271f2920437dff0887e73
https://doi.org/10.1002/(sici)1096-9896(199712)183:4<412::aid-path944>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199712)183:4<412::aid-path944>3.0.co
Publikováno v:
European Journal of Cancer. 33:1846-1850
c-erbB-3, A recently identified member of the type I tyrosine kinase receptor family, has been shown to be overexpressed in invasive ductal carcinoma of breast. In this study, expression of the c-erbB-3 protein was examined in 57 cases of pure ductal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a80e8a5f50603ca8444902e6e17a19
https://doi.org/10.1016/s0959-8049(97)00244-x
https://doi.org/10.1016/s0959-8049(97)00244-x
Publikováno v:
Journal of Clinical Pathology. 50:669-673
AIM: To investigate the relation between angiogenesis and inflammation in invasive carcinoma of the breast. METHODS: Sections from 75 invasive carcinomas of the breast were stained using immunohistochemistry for von Willebrand factor, CD3, CD8, CD45R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b622df9b7d26f84e2d09ade4c621c2ae
https://doi.org/10.1136/jcp.50.8.669
https://doi.org/10.1136/jcp.50.8.669
Publikováno v:
The Journal of Pathology. 181:200-206
Several recent studies suggest that vascular density may be an independent prognostic indicator in invasive carcinoma of the breast. Increased vascularity has also been shown in ductal carcinoma in situ (DCIS). The prognostic significance of the infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd50694979be2b8d0e31c0f177a3048a
https://doi.org/10.1002/(sici)1096-9896(199702)181:2<200::aid-path726>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199702)181:2<200::aid-path726>3.0.co
Publikováno v:
British Journal of Cancer
The significance of inflammation in carcinoma of the breast is controversial. Little attention has been paid to different patterns of inflammation or inflammation associated with different histological types of carcinoma. We have looked at the patter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb752e49922f09f3974102815260fe06
https://doi.org/10.1038/bjc.1996.438
https://doi.org/10.1038/bjc.1996.438
Publikováno v:
Histopathology. 28:301-308
The relevant anti-tumour mechanisms of recombinant interleukin-2 (rIL-2) in vivo are unclear but an influx of T-lymphocytes and macrophages has been noted in regressing lesions. One of the dose limiting toxicities of rIL-2 is the development of a cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8658cdf36d111d17cea32af4e48c71b4
https://doi.org/10.1046/j.1365-2559.1996.d01-430.x
https://doi.org/10.1046/j.1365-2559.1996.d01-430.x
Publikováno v:
The Journal of Pathology. 178:190-194
Laminated occlusive thrombus was induced in the rat inferior vena cava (IVC) by a distal stenosis and injection of thrombin. Immunocytochemistry was performed on serial cryostat sections of the thrombus for tissue plasminogen activator (tPA) and a va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::355f3ca7c7f6b3b42036985ea2dbdf2e
https://doi.org/10.1002/(sici)1096-9896(199602)178:2<190::aid-path454>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199602)178:2<190::aid-path454>3.0.co
Autor:
L C Happerfield, Pete Smith, Walter M Gregory, L.G. Bobrow, David Miles, R D Rubens, R. Gillibrand
Publikováno v:
British Journal of Cancer
Sialyl-Tn (STn) is a carcinoma-associated carbohydrate determinant expressed on cancer-associated mucins and has the structure NANA alpha(2-6)alpha GalNAc. Expression of STn in colon and ovarian cancer is associated with a poor prognosis independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792bd771f6000923cd6f241fbbcbfdec
https://doi.org/10.1038/bjc.1994.486
https://doi.org/10.1038/bjc.1994.486
Autor:
Yataro Daigo, Carlos Caldas, Paul D.P. Pharoah, L.G. Bobrow, Elena Cattaneo, Grace Callagy, L C Happerfield
Publikováno v:
Diagnostic molecular pathology : the American journal of surgical pathology, part B. 12(1)
The histopathologic classification of breast cancer stratifies tumors based on tumor grade, stage, and type. Despite an overall correlation with survival, this classification is poorly predictive and tumors with identical grade and stage can have mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cff45e0f33c19d2dde52658d3503c98
https://pubmed.ncbi.nlm.nih.gov/12605033
https://pubmed.ncbi.nlm.nih.gov/12605033
Publikováno v:
The Journal of pathology. 183(4)
Insulin-like growth factors (IGFs) play an important role in normal cellular growth and development and have been implicated in the regulation of tumour growth. Two receptors are recognized, IGFR-1 and IGFR-2, of which one, IGFR-1, is a transmembrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e410c06d4f98b01cc3c5a948349a127e
https://pubmed.ncbi.nlm.nih.gov/9496257
https://pubmed.ncbi.nlm.nih.gov/9496257