Zobrazeno 1 - 10
of 60
pro vyhledávání: '"L. C. Blaber"'
Autor:
Mullin John Guilfoyle, Herman J. Crowley, Robert William Guthrie, L. C. Blaber, A. Faraone, B. Simko, Francis A. Mennona, R. W. Kierstead
Publikováno v:
Journal of Medicinal Chemistry. 26:1561-1569
A series of binary (aryloxy)propanolamines has been prepared and examined in vitro and in vivo for beta-adrenoreceptor blocking activity. These symmetrical compounds consist of two (S)-(phenyloxy)propanolamine pharmacophores coupled through alkylened
Autor:
L. C. Blaber, W. C. Bowman
Publikováno v:
British Journal of Pharmacology and Chemotherapy. 14:456-466
The effects of edrophonium and choline have been compared with those of the depolarizing substances acetylcholine, decamethonium, and suxamethonium, in both innervated and chronically denervated tibialis anterior muscles of cats under chloralose anae
Autor:
L. C. Blaber
Publikováno v:
British Journal of Pharmacology and Chemotherapy. 15:476-484
The ability of ambenonium and a methoxy analogue to antagonize paralysis produced either by tubocurarine or by decamethonium has been studied in the tibialis anterior muscle of the cat under chloralose anaesthesia. In small doses, both oxamides facil
Autor:
L. C. Blaber
Publikováno v:
British Journal of Pharmacology. 47:109-116
1. Trains of end-plate potentials (e.p.p.s) have been recorded from the isolated tenuissimus of the cat. The muscle was paralyzed either by transversely cutting the muscle fibres or by non-depolarizing blocking drugs. 2. The following parameters of t
Autor:
L. C. Blaber, W. C. Bowman
Publikováno v:
British Journal of Pharmacology and Chemotherapy. 20:326-344
Repetitive discharges recorded from the ventral root and from the gastrocnemius muscle in response to single motor nerve shocks applied close to the muscle after injection of edrophonium, neostigmine or ambenonium were studied in cats anaesthetized w
Autor:
L. C. Blaber
Publikováno v:
British Journal of Pharmacology and Chemotherapy. 20:63-73
A close correlation has been shown to exist between the in vitro anticholinesterase potencies of ambenonium, neostigmine, methoxyambenonium and edrophonium chloride and their abilities to increase muscle contractions produced by close-arterial inject
Autor:
A. G. Karczmar, L. C. Blaber
Publikováno v:
Annals of the New York Academy of Sciences. 144:571-583
Autor:
J. G. Mullin, L. C. Blaber, A. Faraone, B. Simko, Robert William Guthrie, F. A. Mennona, Richard W. Kierstead, Herman J. Crowley
Publikováno v:
Chemischer Informationsdienst. 15
Autor:
P. J. MACHIN, D. N. HURST, R. M. BRADSHAW, L. C. BLABER, D. T. BURDEN, A. D. FRYER, R. A. MELARANGE, C. SHIVDASANI
Publikováno v:
Chemischer Informationsdienst. 15
Publikováno v:
Journal of cardiovascular pharmacology. 6(1)
The effects of bufuralol and its carbinol metabolite have been compared with those of propranolol in the anaesthetised and conscious cat and dog. Bufuralol and its carbinol metabolite are nonselective beta-adrenoceptor antagonists; the former has equ