Zobrazeno 1 - 10
of 32
pro vyhledávání: '"L. Burton Nabors"'
Autor:
Lawrence S. Lamb, Larisa Pereboeva, Samantha Youngblood, G. Yancey Gillespie, L. Burton Nabors, James M. Markert, Anindya Dasgupta, Catherine Langford, H. Trent Spencer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Chemotherapeutic drugs such as the alkylating agent Temozolomide (TMZ), in addition to reducing tumor mass, can also sensitize tumors to immune recognition by transient upregulation of multiple stress induced NKG2D ligands (NKG2DL). However,
Externí odkaz:
https://doaj.org/article/c28e1cc2e93d4747993b3ae118687a18
Autor:
Etty N. Benveniste, Kevin Roarty, Keith Harrison, Cheryl Ann Palmer, Youn-Hee Choi, G. Yancey Gillespie, L. Burton Nabors, Emily C. Brantley
Purpose: STATs activate transcription in response to numerous cytokines, controlling proliferation, gene expression, and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogenesis of many cancers, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224ff55fdcbb8d843ad0bb5dbd46ea49
https://doi.org/10.1158/1078-0432.c.6516970.v1
https://doi.org/10.1158/1078-0432.c.6516970.v1
Autor:
Larisa Pereboeva, Catherine P. Langford, L. Burton Nabors, G. Yancey Gillespie, Anindya Dasgupta, Samantha Youngblood, Lawrence S. Lamb, H. Trent Spencer, James M. Markert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Chemotherapeutic drugs such as the alkylating agent Temozolomide (TMZ), in addition to reducing tumor mass, can also sensitize tumors to immune recognition by transient upregulation of multiple stress induced NKG2D ligands (NKG2DL). However, the pote
Autor:
David K. Crossman, Etty N. Benveniste, J Fraser Humphreys, Hyunmin Koo, Braden C. McFarland, Joseph A. Hakim, Kory Dees, L. Burton Nabors, Casey D. Morrow, Michael R. Crowley
Publikováno v:
Neuro-oncology Advances
Background Although immunotherapy works well in glioblastoma (GBM) preclinical mouse models, the therapy has not demonstrated efficacy in humans. To address this anomaly, we developed a novel humanized microbiome (HuM) model to study the response to
Autor:
Renato V. LaRocca, Reid C. Thompson, Noah C. Peeri, L. Burton Nabors, Travis Gerke, Gabriella M. Anic, Jordan H. Creed, Kathleen M. Egan, Jeffrey J. Olson, John D. Brockman, Sajeel Chowdhary
Publikováno v:
Cancer Epidemiol
Background Selenium is an essential trace element obtained through diet that plays a critical role in DNA synthesis and protection from oxidative damage. Selenium intake and polymorphisms in selenoproteins have been linked to the risk of certain canc
Autor:
Reid C. Thompson, Shitaldas J. Pamnani, Melissa H. Madden, Zachary J. Thompson, Peter A. Forsyth, Gabriella M. Anic, L. Burton Nabors, Jeffrey J. Olson, Kathleen M. Egan, Renato V. LaRocca
Publikováno v:
Journal of Neuro-Oncology. 118:297-304
Gender-specific incidence patterns and the presence of hormonal receptors on tumor cells suggest that sex hormones may play a role in the pathogenesis of primary brain tumors. However, epidemiological studies on the relation of hormonal risk factors
Autor:
Alvaro N.A. Monteiro, L. Burton Nabors, Jeffrey J. Olson, Gabriella M. Anic, Reid C. Thompson, Melissa H. Madden, James E. Browning, Kathleen M. Egan
Publikováno v:
Cancer Causes & Control. 25:25-32
There is growing evidence that circadian disruption may alter risk and aggressiveness of cancer. We evaluated common genetic variants in the circadian gene pathway for associations with glioma risk and patient outcome in a US clinic-based case-contro
Autor:
Reid C. Thompson, James E. Browning, Kathleen M. Egan, Jeffrey J. Olson, Ernest K. Amankwah, Melissa H. Madden, L. Burton Nabors
Publikováno v:
Cancer Epidemiology. 37:162-165
Background : The human SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex plays essential roles in a variety of cellular processes and has been implicated in human cancer. However, the role of germline genetic variants in this comp
Autor:
Kathleen M. Egan, Melissa H. Madden, James E. Browning, Jeffrey J Olson, Alvaro N.A. Monteiro, L. Burton Nabors, Rebekah Baskin, Reid C. Thompson
Publikováno v:
European Journal of Human Genetics. 23:132-134
Genome-wide association studies have recently identified a cancer susceptibility locus at 10p12 mapping to MLLT10 associated with the onset of diverse tumors. We genotyped two tightly linked single-nucleotide polymorphisms (SNPs) at MLLT10 associated
Autor:
Emily C. Brantley, L. Burton Nabors, G. Yancey Gillespie, Kevin Roarty, Cheryl A. Palmer, Etty N. Benveniste, Youn Hee Choi, Keith Harrison
Publikováno v:
Clinical Cancer Research. 14:4694-4704
Purpose: STATs activate transcription in response to numerous cytokines, controlling proliferation, gene expression, and apoptosis. Aberrant activation of STAT proteins, particularly STAT-3, is implicated in the pathogenesis of many cancers, includin