Zobrazeno 1 - 10
of 219
pro vyhledávání: '"L. Burkhart"'
Autor:
Zoe Hall, Catherine H. Wilson, Deborah L. Burkhart, Tom Ashmore, Gerard I. Evan, Julian L. Griffin
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1390-1399 (2020)
Nonsmall cell lung cancer (NSCLC) is a leading cause of cancer-related deaths. While mutations in Kras and overexpression of Myc are commonly found in patients, the role of altered lipid metabolism in lung cancer and its interplay with oncogenic Myc
Externí odkaz:
https://doaj.org/article/94731872d8ec41e79cf6a6bed5eb809f
Autor:
Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan, Catherine H. Wilson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Levels of the transcription factor Myc are deregulated in a range of different cancers. Here the authors show that Myc induces rapid transcriptional responses in some mouse tissues (liver), but not others (heart), and that transcriptional and prolife
Externí odkaz:
https://doaj.org/article/6242a1a22a8f47f48a5d16c07381d895
Autor:
Leigh Ellis, Massimo Loda, Bo Xu, Zafardjan Dalimov, Phillip M. Galbo, David P. Labbé, Kristine M. Wadosky, Katherine L. Morel, Deborah L. Burkhart
Chemoprevention trials for prostate cancer by androgen receptor or androgen synthesis inhibition have proven ineffective. Recently, it has been demonstrated that the histone methlytransferase, EZH2 is deregulated in mouse and human high-grade prostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9549ed71a0cde3b8bdbb4805ed93c85f
https://doi.org/10.1158/1940-6207.c.6547697.v1
https://doi.org/10.1158/1940-6207.c.6547697.v1
Autor:
Leigh Ellis, Massimo Loda, Bo Xu, Zafardjan Dalimov, Phillip M. Galbo, David P. Labbé, Kristine M. Wadosky, Katherine L. Morel, Deborah L. Burkhart
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d71c9767778c873cc2b01118b1131f
https://doi.org/10.1158/1940-6207.22534898.v1
https://doi.org/10.1158/1940-6207.22534898.v1
Autor:
Julian L. Griffin, Gerard I. Evan, Trevor Littlewood, Albert Koulman, Tom Ashmore, Deborah L. Burkhart, Catherine H. Wilson, Zsuzsanna Ament, Zoe Hall
Relative abundances of free fatty acids, phosphatidylglycerols and phosphatidylinositols in tumour compared to normal lung tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342614b219d5bb2f551db277d1a7e990
https://doi.org/10.1158/0008-5472.22410917.v1
https://doi.org/10.1158/0008-5472.22410917.v1
Autor:
Julian L. Griffin, Gerard I. Evan, Trevor Littlewood, Albert Koulman, Tom Ashmore, Deborah L. Burkhart, Catherine H. Wilson, Zsuzsanna Ament, Zoe Hall
Figure legends for supplemental Figures S1-S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459bb0114244c72875e0d65f6ab33318
https://doi.org/10.1158/0008-5472.22410902.v1
https://doi.org/10.1158/0008-5472.22410902.v1
Autor:
Julian L. Griffin, Gerard I. Evan, Trevor Littlewood, Albert Koulman, Tom Ashmore, Deborah L. Burkhart, Catherine H. Wilson, Zsuzsanna Ament, Zoe Hall
MYC-mediated pathogenesis in lung cancer continues to attract interest for new therapeutic strategies. In this study, we describe a transgenic mouse model of KRAS-driven lung adenocarcinoma that affords reversible activation of MYC, used here as a to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c856fd3197712afcbc9dfb3dddd2b2c1
https://doi.org/10.1158/0008-5472.c.6508106.v1
https://doi.org/10.1158/0008-5472.c.6508106.v1
Autor:
Julian L. Griffin, Gerard I. Evan, Trevor Littlewood, Albert Koulman, Tom Ashmore, Deborah L. Burkhart, Catherine H. Wilson, Zsuzsanna Ament, Zoe Hall
LC-MS/MS method details for eicosanoid analysis (Tables S1 and S2); Lipid ID by accurate mass and tandem MS (Tables S3 and S4); Fold change for eicosanoid-related species with MYC activated (Table S5).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8e9f1fc1d99bd0f466a9dd68b12f9b
https://doi.org/10.1158/0008-5472.22410899
https://doi.org/10.1158/0008-5472.22410899
Autor:
Julien Sage, E. Alejandro Sweet-Cordero, Anthony N. Karnezis, Deborah L. Burkhart, Chenwei Lin, Jamie F. Conklin, Gloria Yiu, Kwon-Sik Park, Bethany E. Schaffer
Supplementary Figure 6A from Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a9f5f7eac692bf856b648157e18f3e
https://doi.org/10.1158/0008-5472.22383335.v1
https://doi.org/10.1158/0008-5472.22383335.v1
Autor:
Julien Sage, E. Alejandro Sweet-Cordero, Anthony N. Karnezis, Deborah L. Burkhart, Chenwei Lin, Jamie F. Conklin, Gloria Yiu, Kwon-Sik Park, Bethany E. Schaffer
Supplementary Figure 2 from Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5327b4a308b7e187aa55f6d57bd7cc
https://doi.org/10.1158/0008-5472.22383350.v1
https://doi.org/10.1158/0008-5472.22383350.v1