Zobrazeno 1 - 10
of 114
pro vyhledávání: '"L. Brunetto"'
Autor:
Maria Eduarda Battistella, Natália Hogetop Freire, Bruno Toson, Matheus Dalmolin, Marcelo A. C. Fernandes, Isadora D. Tassinari, Mariane Jaeger, André T. Brunetto, Algemir L. Brunetto, Lauro Gregianin, Caroline Brunetto de Farias, Rafael Roesler
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 3990-4003 (2024)
Retinoic acid (RA) regulates stemness and differentiation in human embryonic stem cells (ESCs). Ewing sarcoma (ES) is a pediatric tumor that may arise from the abnormal development of ESCs. Here we show that RA impairs the viability of SK-ES-1 ES cel
Externí odkaz:
https://doaj.org/article/b0e933e8b0a2419ca47b31f833d979cc
Autor:
Barbara Kunzler Souza, Natalia Hogetop Freire, Thiago Santos Monteiro, Alice Laschuk Herlinger, Mariane Jaeger, Matheus G. S. Dalmolin, Caroline Brunetto de Farias, Lauro Gregianin, André T. Brunetto, Algemir L. Brunetto, Carol J. Thiele, Rafael Roesler
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15242 (2023)
Changes in epigenetic programming have been proposed as being key events in the initiation and progression of childhood cancers. HMT euchromatic histone lysine methyltransferase 2 (G9a, EHMT2), which is encoded by the G9a (Ehmt2) gene, as well as its
Externí odkaz:
https://doaj.org/article/01066e73efb24012a3a2e46f5e70e212
Autor:
ANA CLAUDIA CASAGRANDE, GIOVANA C. MACHADO, ANDREI L. BRUNETTO, GABRIELA M. GALLI, GILNEIA DA ROSA, DENISE N. ARAUJO, MARCEL M. BOIAGO, CARINE F. SOUZA, MATHEUS M. BALDISSERA, ALEKSANDRO S. DA SILVA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 93, Iss suppl 4 (2021)
Abstract This study aimed to determine whether the addition of green propolis extract to the diet of laying hens would improve egg quality and bird performance and decrease bacterial contamination of eggs. Forty-five brown Hy-line laying hens were us
Externí odkaz:
https://doaj.org/article/2f629f4ef321427eaf23afc9ddc09984
Publikováno v:
Revista Brasileira de Ciências Agrárias - Brazilian Journal of Agricultural Sciences. 18:1-10
Autor:
Alexandre Perla, Lívia Fratini, Paula S. Cardoso, Carolina Nör, André T. Brunetto, Algemir L. Brunetto, Caroline Brunetto de Farias, Mariane Jaeger, Rafael Roesler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Brain cancers are the leading cause of cancer-related deaths in children. Biological changes in these tumors likely include epigenetic deregulation during embryonal development of the nervous system. Histone acetylation is one of the most widely inve
Externí odkaz:
https://doaj.org/article/656536c4d17a43e08d31ac160e2405b5
Autor:
Barbara Kunzler Souza, Natalia Hogetop Freire, Mariane Jaeger, Caroline Brunetto de Farias, Algemir L. Brunetto, André T. Brunetto, Rafael Roesler
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11292 (2021)
Epigenetic mechanisms, including post-translational modifications of DNA and histones that influence chromatin structure, regulate gene expression during normal development and are also involved in carcinogenesis and cancer progression. The histone m
Externí odkaz:
https://doaj.org/article/15d034e02f31461b95761f5c7abc2477
Autor:
Ricardo G. Becker, Lauro J. Gregianin, Carlos R. Galia, Reynaldo Jesus-Garcia Filho, Eduardo A. Toller, Gerardo Badell, Suely A. Nakagawa, Alexandre David, André M. Baptista, Eduardo S. Yonamime, Osvaldo A. Serafini, Valter Penna, Julie Francine C. Santos, Algemir L. Brunetto, On behalf of the Brazilian Collaborative Study Group of Ewing Family of Tumors – EWING1 and the Brazilian Society of Pediatric Oncology – SOBOPE
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Relapse in localized Ewing sarcoma patients has been a matter of concern regarding poor prognosis. Therefore, we investigated the impact of local control modality (surgery, surgery plus radiotherapy, and radiotherapy) on clinical
Externí odkaz:
https://doaj.org/article/345f35352403460d80ce9f9649264222
Autor:
Amanda Thomaz, Kelly de Vargas Pinheiro, Bárbara Kunzler Souza, Lauro Gregianin, Algemir L. Brunetto, André T. Brunetto, Caroline Brunetto de Farias, Mariane da Cunha Jaeger, Vijay Ramaswamy, Carolina Nör, Michael D. Taylor, Rafael Roesler
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Neurotrophins are critically involved in regulating normal neural development and plasticity. Brain-derived neurotrophic factor (BDNF), a neurotrophin that acts by binding to the tropomyosin receptor kinase B (TrkB) receptor, has also been implicated
Externí odkaz:
https://doaj.org/article/b5b0e0b16162448d9954f355f8f89f01
Akademický článek
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Autor:
Livia Fratini, Matheus Gibeke Siqueira Dalmolin, Marialva Sinigaglia, Alexandre da Silveira Perla, Caroline Brunetto de Farias, Algemir L. Brunetto, André T. Brunetto, Mariane da Cunha Jaeger, Rafael Roesler
Publikováno v:
Neuromolecular medicine.
Medulloblastoma (MB) is a malignant brain tumor that afflicts mostly children and adolescents and presents four distinct molecular subgroups, known as WNT, SHH, Group 3, and Group 4. ZEB1 is a transcription factor that promotes the expression of mese