Zobrazeno 1 - 10 of 23 pro vyhledávání: '"L. Blauw"'
1
Variants in the
Autor: Antoine, Rimbert, Ming W, Yeung, Nawar, Dalila, Chris H L, Thio, Haojie, Yu, Natalia, Loaiza, Federico, Oldoni, Adriaan, van der Graaf, Siqi, Wang, M Abdullah, Said, Lisanne L, Blauw, Aurore, Girardeau, Lise, Bray, Amandine, Caillaud, Vincent W, Bloks, Marie, Marrec, Philippe, Moulin, Patrick C N, Rensen, Bart, van de Sluis, Harold, Snieder, Mathilde, Di Filippo, Pim, van der Harst, Anne, Tybjaerg-Hansen, Philip, Zimmerman, Bertrand, Cariou, Jan Albert, Kuivenhoven
Publikováno v: Arteriosclerosis, thrombosis, and vascular biology. 42(10)
In mice, GPR146 (G-protein-coupled receptor 146) deficiency reduces plasma lipids and protects against atherosclerosis. Whether these findings translate to humans is unknown.Common and rare genetic variants in theIn the UK Biobank, carriers of the co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87e391709d86a41f5fff02f40557b147
https://pubmed.ncbi.nlm.nih.gov/36047410
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2
Akademický článek
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3
Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile
Autor: Antoine Rimbert, Ming W. Yeung, Nawar Dalila, Chris H.L. Thio, Haojie Yu, Natalia Loaiza, Federico Oldoni, Adriaan van der Graaf, Siqi Wang, M. Abdullah Said, Lisanne L. Blauw, Aurore Girardeau, Lise Bray, Amandine Caillaud, Vincent W. Bloks, Marie Marrec, Philippe Moulin, Patrick C.N. Rensen, Bart van de Sluis, Harold Snieder, Mathilde Di Filippo, Pim van der Harst, Anne Tybjaerg-Hansen, Philip Zimmerman, Bertrand Cariou, Jan Albert Kuivenhoven
Publikováno v: Rimbert, A, Yeung, M W, Dalila, N, Thio, C H L, Yu, H, Loaiza, N, Oldoni, F, van der Graaf, A, Wang, S, Said, M A, Blauw, L L, Girardeau, A, Bray, L, Caillaud, A, Bloks, V W, Marrec, M, Mouli, P, Rensen, P C N, van de Sluis, B, Snieder, H, Di Filippo, M, van der Harst, P, Tybjaerg-Hansen, A, Zimmerman, P, Cariou, B & Kuivenhoven, J A 2022, ' Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile ', Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 42, no. 10, pp. 1262-1271 . https://doi.org/10.1161/ATVBAHA.122.317514
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, 2022, 42 (10), pp.1262-1271. ⟨10.1161/atvbaha.122.317514⟩
Arteriosclerosis, thrombosis, and vascular biology, 42(10), 1262-1271. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology, 42(10), 1262-1271. LIPPINCOTT WILLIAMS & WILKINS
Background:In mice, GPR146 (G-protein–coupled receptor 146) deficiency reduces plasma lipids and protects against atherosclerosis. Whether these findings translate to humans is unknown.Methods:Common and rare genetic variants in theGPR146gene locus
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb70fea5501d89e9dcbe494d7a9b727
https://curis.ku.dk/ws/files/320753917/ATVBAHA.122.317514.pdf
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5
Hepatic triglyceride content does not affect circulating CETP: lessons from a liraglutide intervention trial and a population-based cohort
Autor: Lisanne L. Blauw, Yanan Wang, Huub J. van Eyk, Renée de Mutsert, Johannes W. A. Smit, Patrick C.N. Rensen, Ingrid M. Jazet, Ko Willems van Dijk, Hildo J. Lamb, Maurice B. Bizino
Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports, 9. NATURE PUBLISHING GROUP
Scientific Reports, 9
Scientific Reports
Cholesteryl ester transfer protein (CETP) is mainly expressed by Kupffer cells in the liver. A reduction of hepatic triglyceride content (HTGC) by pioglitazone or caloric restriction is accompanied by a decrease in circulating CETP. Since GLP-1 analo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2804fabe1cb21b66810769e2dab46423
http://link.springer.com/article/10.1038/s41598-019-45593-2
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6
Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis
Autor: Lisanne L. Blauw, Liam R. Brunham, HyeJin Julia Kong, Yanan Wang, John H. Boyd, James A. Russell, Mihai Cirstea, Cody Lo, Kelly R. Genga, Patrick C.N. Rensen, Keith R. Walley, Xuan Li, Mark Trinder
Publikováno v: American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine, 199(7), 854-862. AMER THORACIC SOC
Rationale: High-density lipoprotein (HDL) cholesterol (HDL-C) levels decline during sepsis, and lower levels are associated with worse survival. However, the genetic mechanisms underlying changes in HDL-C during sepsis, and whether the relationship w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee66358a3246e18bd48449f9e47f627
https://doi.org/10.1164/rccm.201806-1157oc
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7
Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis
Autor: Lubos Bohunek, Keith R. Walley, Liam R. Brunham, John H. Boyd, Brendan A. Daisely, Mark Trinder, Mark M. Wurfel, Christian M. Madsen, James A. Russell, Lisanne L. Blauw, Anne Tybjærg-Hansen, Patrick C.N. Rensen, Yanan Wang, Børge G. Nordestgaard, Tatjana Ponomarev, HyeJin Julia Kong
Publikováno v: Circulation, 143(9), 921-934. LIPPINCOTT WILLIAMS & WILKINS
Background: The high-density lipoprotein hypothesis of atherosclerosis has been challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors, which failed to show significant reductions in cardiovascular events. Plasma levels
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8403e40d2972efb108c216751e6a1b9
https://hdl.handle.net/1887/3563475
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8
Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes
Autor: Johan Wouter Jukema, Lisanne L. Blauw, Stella Trompet, Sander Kooijman, Jimmy F.P. Berbée, Anne Tybjærg-Hansen, Raymond Noordam, Gerard Pasterkamp, Gert J. de Borst, Diana van Heemst, Sander W. van der Laan, Patrick C.N. Rensen, Jessica van Setten
Publikováno v: Blauw, L L, Noordam, R, van der Laan, S W, Trompet, S, Kooijman, S, van Heemst, D, Jukema, J W, van Setten, J, de Borst, G J, Tybjærg-Hansen, A, Pasterkamp, G, Berbée, J F P & Rensen, P C N 2021, ' Common genetic variation in mc4r does not affect atherosclerotic plaque phenotypes and cardiovascular disease outcomes ', Journal of Clinical Medicine, vol. 10, no. 5, 932 . https://doi.org/10.3390/jcm10050932
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 932, p 932 (2021)
Volume 10
Issue 5
Journal of Clinical Medicine, 10(5). MDPI
We analyzed the effects of the common BMI-increasing melanocortin 4 receptor (MC4R) rs17782313-C allele with a minor allele frequency of 0.22–0.25 on (1) cardiovascular disease outcomes in two large population-based cohorts (Copenhagen City Heart S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a832869788750225e29412aa98ab773
https://pubmed.ncbi.nlm.nih.gov/33804309
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10
Genome-wide association study of the postprandial triglyceride response yields common genetic variation in LIPC (hepatic lipase)
Autor: Raymond Noordam, Diana van Heemst, Lisanne L. Blauw, Dorina Ibi, Ruifang Li-Gao, Tim Christen, Renée de Mutsert, Ko Willems van Dijk, J. Wouter Jukema, Jan B. van Klinken, Martijn E.T. Dollé, Dennis O. Mook-Kanamori, Frits R. Rosendaal, Stella Trompet, Patrick C.N. Rensen
Publikováno v: Circulation: Genomic and Precision Medicine, 13(4), 289-297. LIPPINCOTT WILLIAMS & WILKINS
Circulation. Genomic and precision medicine, 13(4), 289-297. Lippincott Williams and Wilkins Ltd.
Background: The increase in serum triglyceride (TG) concentrations in response to a meal is considered a risk factor for cardiovascular disease. We aimed to elucidate the genetics of the postprandial TG response through genome-wide association studie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68dfa862d2a435f2a8d6a33a230bf0b5
http://hdl.handle.net/1887/3182376
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