Zobrazeno 1 - 10
of 257
pro vyhledávání: '"L. Blau"'
Publikováno v:
Revista de Ciências Farmacêuticas Básica e Aplicada, Vol 29, Iss 3, Pp 231-238 (2009)
Durante o planejamento estrutural de novos fármacos, é possível prever a infl uência de grupamentos específi cos na atividade farmacológica. Entre estes, encontrase o grupo nitro, que possui potencial atividade antimicrobiana, estando presente
Externí odkaz:
https://doaj.org/article/18a3f6664d5449ec8b3438044dec5d37
Autor:
J. L. SANTOS, L. BLAU, R. F. MENEGON, H. P. OLIVEIRA, R. H. BUELONI, E. BOFFO, R. G.P. MACHADO, M. C. LONGO, M. C. CHUNG
Publikováno v:
Revista de Ciências Farmacêuticas Básica e Aplicada, Vol 28, Iss 2, Pp 235-240 (2009)
Os fármacos antiinflamatórios são sabidamente os mais comercializados em todo o mundo, e apesar disto apresentam sérios efeitos colaterais, sobretudo no que se refere ao trato gastrintestinal. A descoberta de novos protótipos com atividade e seg
Externí odkaz:
https://doaj.org/article/013bb2e09e1040caa6def6cc4975112c
Publikováno v:
Revista de Ciências Farmacêuticas Básica e Aplicada, Vol 29, Iss 3 (2008)
Durante o planejamento estrutural de novos fármacos, é possível prever a influência de grupamentos específicos na atividade farmacológica. Entre estes, encontrase o grupo nitro, que possui potencial atividade antimicrobiana, estando presente em
Externí odkaz:
https://doaj.org/article/e6b864c5b9a94cb7abf4008ebe4f4b11
Autor:
J.L. Santos, L. Blau, R.F. Menegon, H.P. Oliveira, R.H. Bueloni, E. Boffo, R.G.P. Machado, M.C. Longo, M.C. Chung
Publikováno v:
Revista de Ciências Farmacêuticas Básica e Aplicada, Vol 28, Iss 2 (2007)
Os fármacos antiinflamatórios são sabidamente os mais comercializados em todo o mundo, e apesar disto apresentam sérios efeitos colaterais, sobretudo no que se refere ao trato gastrintestinal. A descoberta de novos protótipos com atividade e seg
Externí odkaz:
https://doaj.org/article/0c03ec24a6734b4b8d37202c2d718f36
Autor:
Diane M. Simeone, Mark M. Zalupski, Ulysses G. Balis, Ronald Craig, John L. Blau, Gazala N. Khan, Naoko Takebe, Joel K. Greenson, Kent A. Griffith, Ethan V. Abel, Vaibhav Sahai, Edward J. Kim
Supplementary Figure 1 Legend. Median overall survival correlated with change in CA 19-9 (>50% decrease, versus {less than or equal to}50% decrease, or primary increase)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17864c07d9ce37b89b66ed47d18fc192
https://doi.org/10.1158/1078-0432.22455356
https://doi.org/10.1158/1078-0432.22455356
Autor:
Diane M. Simeone, Mark M. Zalupski, Ulysses G. Balis, Ronald Craig, John L. Blau, Gazala N. Khan, Naoko Takebe, Joel K. Greenson, Kent A. Griffith, Ethan V. Abel, Vaibhav Sahai, Edward J. Kim
Supplementary Figure 1. Median overall survival correlated with change in CA 19-9 (>50% decrease, versus {less than or equal to}50% decrease, or primary increase) compared to baseline.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c61f6e10f6eb68ead9c3b423a8b1df2
https://doi.org/10.1158/1078-0432.22455353.v1
https://doi.org/10.1158/1078-0432.22455353.v1
Autor:
Diane M. Simeone, Mark M. Zalupski, Ulysses G. Balis, Ronald Craig, John L. Blau, Gazala N. Khan, Naoko Takebe, Joel K. Greenson, Kent A. Griffith, Ethan V. Abel, Vaibhav Sahai, Edward J. Kim
Purpose: The hedgehog (HH) signaling pathway is a key regulator in tumorigenesis of pancreatic adenocarcinoma and is upregulated in pancreatic adenocarcinoma cancer stem cells (CSCs). GDC-0449 is an oral small-molecule inhibitor of the HH pathway. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e05e5a8257116fababcd5bd39db9801
https://doi.org/10.1158/1078-0432.c.6523001.v1
https://doi.org/10.1158/1078-0432.c.6523001.v1
Autor:
Diane M. Simeone, Mark M. Zalupski, Ulysses G. Balis, Ronald Craig, John L. Blau, Gazala N. Khan, Naoko Takebe, Joel K. Greenson, Kent A. Griffith, Ethan V. Abel, Vaibhav Sahai, Edward J. Kim
Supplementary Table 1. Summary of Treatment-Related Adverse Events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28abe1a90f256462e36627e451e04b81
https://doi.org/10.1158/1078-0432.22455350
https://doi.org/10.1158/1078-0432.22455350
Publikováno v:
Studies in Big Data ISBN: 9783031294884
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0031bfeaa0d2779df342047aef34c1d5
https://doi.org/10.1007/978-3-031-29489-1_27
https://doi.org/10.1007/978-3-031-29489-1_27
Autor:
Joseph Laakman, Kyle S Conway, John L Blau, Amy C Gottschalk, Marcus B. Nashelsky, Renee L Eigsti, Marco M. Hefti, Fozia Ghafoor
Publikováno v:
J Neuropathol Exp Neurol
1p36 deletion syndrome is the most common terminal deletion syndrome, manifesting clinically as abnormal facies and developmental delay with frequent cardiac, skeletal, urogenital, and renal abnormalities. Limited autopsy case reports describe the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce15f070a2c98de33d5c42d561013b1
https://doi.org/10.1093/jnen/nlab072
https://doi.org/10.1093/jnen/nlab072