Zobrazeno 1 - 10
of 317
pro vyhledávání: '"L. Baggio"'
Autor:
Leticia Forny Germano, Jacqueline A. Koehler, Laurie L. Baggio, Fiona Cui, Chi Kin Wong, Nikolaj Rittig, Xiemin Cao, Dianne Matthews, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102019- (2024)
Objective: The development of glucagon-like peptide-1 receptor (GLP-1R) agonists for the treatment of type 2 diabetes and obesity has been accompanied by evidence for anti-inflammatory and cytoprotective actions in the heart, blood vessels, kidney, a
Externí odkaz:
https://doaj.org/article/251c6b672668429ebb6e64cd03609235
Autor:
Thao D.V. Le, Payam Fathi, Amanda B. Watters, Blair J. Ellis, Gai-Linn K. Besing, Nadejda Bozadjieva-Kramer, Misty B. Perez, Andrew I. Sullivan, Jesse P. Rose, Laurie L. Baggio, Jacqueline Koehler, Jennifer L. Brown, Michelle B. Bales, Kaitlyn G. Nwaba, Jonathan E. Campbell, Daniel J. Drucker, Matthew J. Potthoff, Randy J. Seeley, Julio E. Ayala
Publikováno v:
Molecular Metabolism, Vol 72, Iss , Pp 101718- (2023)
Objective: Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1RA) and fibroblast growth factor-21 (FGF21) confer similar metabolic benefits. GLP-1RA induce FGF21, leading us to investigate mechanisms engaged by the GLP-1RA liraglutide to increa
Externí odkaz:
https://doaj.org/article/d72c33cca2fa47dca8da218c427827be
Autor:
Gemma Pujadas, Laurie L. Baggio, Kiran Deep Kaur, Brent A. McLean, Xiemin Cao, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 65, Iss , Pp 101586- (2022)
Objective: The gut hormone glucose-dependent insulinotropic polypeptide (GIP) stimulates beta cell function and improves glycemia through its incretin actions. GIP also regulates endothelial function and suppresses adipose tissue inflammation through
Externí odkaz:
https://doaj.org/article/7e70eb06308240b68752d72f802653ba
Autor:
Laurie L. Baggio, Elodie M. Varin, Jacqueline A. Koehler, Xiemin Cao, Yuliya Lokhnygina, Susanna R. Stevens, Rury R. Holman, Daniel J. Drucker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
DPP4 inhibitors are used for the treatment of diabetes, but the impact of DPP4 activity and soluble DPP4 on development of diabetes-associated inflammation remains uncertain. Here the authors study whether DPP4 inhibition controls sDPP4 and inflammat
Externí odkaz:
https://doaj.org/article/cfbe57d96821439588f72940834dce14
Autor:
Kiran Deep Kaur, Chi Kin Wong, Laurie L. Baggio, Jacqueline L. Beaudry, Shai Fuchs, Brandon L. Panaro, Dianne Matthews, Xiemin Cao, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 48, Iss , Pp 101213- (2021)
Objective: Glucose-dependent insulinotropic polypeptide (GIP) and Glucagon-like peptide-1 (GLP-1) are incretin hormones that exert overlapping yet distinct actions on islet β-cells. We recently observed that GIP, but not GLP-1, upregulated islet exp
Externí odkaz:
https://doaj.org/article/912c0af51d7541668866e9c08d11779d
Autor:
Jacqueline L. Beaudry, Kiran D. Kaur, Elodie M. Varin, Laurie L. Baggio, Xiemin Cao, Erin E. Mulvihill, Holly E. Bates, Jonathan E. Campbell, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 28, Iss , Pp 14-25 (2019)
Objective: Glucose-dependent insulinotropic polypeptide (GIP) is secreted from the gut in response to nutrient ingestion and promotes meal-dependent insulin secretion and lipid metabolism. Loss or attenuation of GIP receptor (GIPR) action leads to re
Externí odkaz:
https://doaj.org/article/74333548414145d59b6704366a4af522
Autor:
Jacqueline L. Beaudry, Kiran Deep Kaur, Elodie M. Varin, Laurie L. Baggio, Xiemin Cao, Erin E. Mulvihill, Jennifer H. Stern, Jonathan E. Campbell, Phillip E. Scherer, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 22, Iss , Pp 37-48 (2019)
Objective: Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although t
Externí odkaz:
https://doaj.org/article/34b08743c20a4fa3babce0d5ea0b6b24
Publikováno v:
Class.Quant.Grav.25:095004,2008
The first simultaneous operation of the AURIGA detector and the LIGO observatory was an opportunity to explore real data, joint analysis methods between two very different types of gravitational wave detectors: resonant bars and interferometers. This
Externí odkaz:
http://arxiv.org/abs/0710.0497
Autor:
Laurie L. Baggio, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 46, Iss , Pp 101090- (2021)
Background: Glucagon-like peptide-1 receptor (GLP-1R) agonists are approved to treat type 2 diabetes and obesity. They elicit robust improvements in glycemic control and weight loss, combined with cardioprotection in individuals at risk of or with pr
Externí odkaz:
https://doaj.org/article/5d1268b0fcd0471d85db9856c8d93b62
Autor:
Gemma Pujadas, Elodie M. Varin, Laurie L. Baggio, Erin E. Mulvihill, K.W.Annie Bang, Jacqueline A. Koehler, Dianne Matthews, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 39, Iss , Pp 101008- (2020)
Objective: Glucose-dependent insulinotropic polypeptide (GIP) conveys information from ingested nutrients to peripheral tissues, signaling energy availability. The GIP Receptor (GIPR) is also expressed in the bone marrow, notably in cells of the myel
Externí odkaz:
https://doaj.org/article/e19fde8ee5ec4243954f64ec98a8f79f