Výsledky vyhledávání - "L. B. Overacre"

Molecular Structures and Conformational Studies of Triarylcyclopropyl and Related Nonsteroidal Anti-Estrogens

Autor: K. L. Meyer, L. B. Overacre, Evamarie O. Pordesimo, R. A. Magarian, Francis J. Schmitz, B. W. Day, M. B. Hossain, D. Van Der Helm

Publikováno v: Journal of Medicinal Chemistry. 37:1670-1683

Molecular structures and conformational characteristics of a series of 1,1-dichloro-2,2,3-triarylcyclopropanes (DTACs), which were reported previously to be distinctly antiestrogenic and inhibitors of the estrogen-receptor-positive MCF-7 human breast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd62adeceb5773959739d609d409ffc8
https://doi.org/10.1021/jm00037a018

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Synthesis and biological evaluation of basic side chain derivatives of Analog II as pure antiestrogens and antitumor agents

Autor: R A, Magarian, K S, Avor, L B, Overacre, J, Kunchandy, T R, Paxton

Publikováno v: Anti-cancer drug design. 10(4)

In an effort to prepare effective non-steroidal antiestrogens without intrinsic estrogenicity and with greater antagonism than those of the triarylethylenes (tamoxifen; TAM) four N-substituted (Z)-1,1-dichloro-2-[4-(2-aminoethoxy)phenyl]-3-phenylcycl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19744a8c174be1d7600fa4acd4695254
https://pubmed.ncbi.nlm.nih.gov/7786397

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