Zobrazeno 1 - 10
of 74
pro vyhledávání: '"L. B. Lachman"'
Publikováno v:
Ultrasound in Medicine & Biology. 29:1291-1296
To test the feasibility of applying ultrasonic elastography on small animal oncology models, experiments were performed in vitro and in situ on murine mammary lesions induced exogenously by tumor cell line 66.3. In vitro studies involved three 1-week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddda6fe225bee482bc59f5c5d0d7743d
https://doi.org/10.1016/s0301-5629(03)01013-5
https://doi.org/10.1016/s0301-5629(03)01013-5
Autor:
Ronald H. Kremer, Galina Kiriakova, Xiao Mei Rao, Janet E. Price, L. B. Lachman, Bulent Ozpolat
Publikováno v:
Cancer Gene Therapy. 8:259-268
The gene for HER2/neu is overexpressed in 30–40% of breast and ovarian cancers, and this overexpression correlates with increased metastasis and poor prognosis. The HER2/neu gene product, a transmembrane protein kinase member of the EGF receptor fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acc32eb0ddbaf955f8b6605580ff0c3
https://doi.org/10.1038/sj.cgt.7700300
https://doi.org/10.1038/sj.cgt.7700300
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 3:289-302
Vaccination against Helicobacter pylori using DNA sequences encoding Urease A and B subunits was compared to immunization with urease antigen and MTP-PE in a liposome formulation. To determine the effectiveness of a vaccine against H. pylori in a mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7117c74225ae2c7cee8831a4bff0d5
https://doi.org/10.2174/1386207003331526
https://doi.org/10.2174/1386207003331526
Publikováno v:
Cytokine. 4:106-113
Lipopolysaccharide (LPS) either in its soluble form or associated with multilamellar phospholipid vesicles (liposomes) was investigated for its ability to induce human monocyte interleukin (IL)-1 alpha and IL-1 beta. When human monocytes were activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb32fbdb977eb494fafa331b160e6f5
https://doi.org/10.1016/1043-4666(92)90045-s
https://doi.org/10.1016/1043-4666(92)90045-s
Publikováno v:
The Journal of Immunology. 148:84-91
In an attempt to define the mechanism by which endotoxin induces its biologic activity, LPS was incorporated into phospholipid vesicles (liposomes) and compared with free LPS for ability to stimulate human monocytes. Activation of human monocytes by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3422b5fa6cd6bfe3ff16bf49429fbc3c
https://doi.org/10.4049/jimmunol.148.1.84
https://doi.org/10.4049/jimmunol.148.1.84
Publikováno v:
The Journal of Immunology. 147:2164-2169
To determine whether membrane-associated IL-1 is palmitylated, we labeled LPS-activated human monocytes with [3H]palmitic acid. The plasma membranes were isolated, and the membrane proteins extracted and analyzed simultaneously by SDS-PAGE-autoradiog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b48cdf972b2dfa6898e02e53eb61e4
https://doi.org/10.4049/jimmunol.147.7.2164
https://doi.org/10.4049/jimmunol.147.7.2164
Autor:
Bulent Ozpolat, L. B. Lachman
Publikováno v:
Vaccine Adjuvants and Delivery Systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98f1bddc2c8b27c7d383fa8f29626a2
https://doi.org/10.1002/9780470134931.ch11
https://doi.org/10.1002/9780470134931.ch11
Publikováno v:
Gene therapy. 14(4)
Melanoma patients with metastases have a very low survival rate and limited treatment options. Therefore, the targeting of melanoma cells when they begin to invade and metastasize would be beneficial. An adhesion molecule that is upregulated at the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39d001ac572df27ce5c5977616aaf24
https://pubmed.ncbi.nlm.nih.gov/17024104
https://pubmed.ncbi.nlm.nih.gov/17024104
Autor:
Bulent Ozpolat, L. B. Lachman
Publisher Summary The use of adjuvants is critical for the development of successful subunit vaccines because most peptide antigens are either non-immunogenic or weakly immunogenic. Adjuvants provide a mechanism for antigen persistence at the injecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e9dbb81e3360569a1f7400b74efed0f
https://doi.org/10.1016/s0076-6879(03)73006-7
https://doi.org/10.1016/s0076-6879(03)73006-7
Helicobacter pyloriis one of the most common chronic infections in humans, in whom it is a key etiological factor in peptic ulcer disease, gastric mucosa-associated lymphoid tissue lymphoma, and gastric adenocarcinoma. Humans are the bacterium's only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9613361e3bb470e417ac2211e43f1b
https://europepmc.org/articles/PMC130860/
https://europepmc.org/articles/PMC130860/