Subgrouping of patients with oral lichen planus according to cytochrome P450 enzyme phenotype and genotype

Autor: Camilla Kragelund, K. Broesen, L. A. Torpet, Jesper Reibel, Siri Beier Jensen, C. Hansen Cand Scient

Publikováno v: Kragelund, C, Jensen, S B, Scient, C H C, Brøsen, K, Torpet, L A & Reibel, J 2014, ' Subgrouping of patients with oral lichen planus according to cytochrome P450 enzyme phenotype and genotype ', Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, vol. 118, no. 4, pp. 469-474 . https://doi.org/10.1016/j.oooo.2014.06.008

Objective This study aimed to determine if the activity of the environmentally influenced cytochrome P450 enzyme CYP1A2, alone or in combination with CYP2D6*4 genotype, discriminates subgroups of oral lichen planus (OLP) according to lifestyle factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc5793d4d576078e72384c424ec039e
https://doi.org/10.1016/j.oooo.2014.06.008

Associations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older people

Autor: Dorte Smidt, Anne Marie Lynge Pedersen, Birgitte Nauntofte, L. A. Torpet, Karen Margrethe Heegaard

Publikováno v: Community Dentistry and Oral Epidemiology. 38:422-435

Smidt D, Torpet LA, Nauntofte B, Heegaard KM, Pedersen AML. Associations between labial and whole salivary flow rates, systemic diseases and medications in a sample of older people. Community Dent Oral Epidemiol 2010; 38: 422–435. © 2010 John Wile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9202636a35ed5e5a3cfc679b95abcba2
https://doi.org/10.1111/j.1600-0528.2010.00554.x

Polymorphic drug metabolizing CYP-enzymes - a pathogenic factor in oral lichen planus?

Autor: Birgitte Nauntofte, L. A. Torpet, Hans Eiberg, Claus Hansen, K. Broesen, Anne Marie Lynge Pedersen, D. Smidt, Jesper Reibel, Camilla Kragelund

Publikováno v: Journal of Oral Pathology & Medicine. 38:63-71

Background: Oral lichen planus (OLP) is a chronic mucosal disease with a characteristic clinical phenotype. Environmental exposures, e.g. drugs have been associated with the pathogenesis. Objectives: To test the hypothesis that some OLP lesions have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d796a60ffd9b1a57c834d9e8725b9e2
https://doi.org/10.1111/j.1600-0714.2008.00702.x

Oral Adverse Drug Reactions to Cardiovascular Drugs

Autor: L. A. Torpet, Jesper Reibel, Camilla Kragelund, Birgitte Nauntofte

Publikováno v: Critical Reviews in Oral Biology & Medicine. 15:28-46

A great many cardiovascular drugs (CVDs) have the potential to induce adverse reactions in the mouth. The prevalence of such reactions is not known, however, since many are asymptomatic and therefore are believed to go unreported. As more drugs are m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b26a2044311ec2ecb3373099d7354f
https://doi.org/10.1177/154411130401500104

An Ultrastructural Evaluation of the SKIN2™ ZK1200 System as an in Vitro Model of the Human Oral Mucosa

Autor: L. A. Torpet, Kaj Josephsen, Dorthe Arenholt-Bindslev

Publikováno v: Alternatives to Laboratory Animals. 25:263-270

At present, there are no validated experimental models for the preclinical oral mucosa irritancy screening of dental materials and oral hygiene products. Standardised in vitro models for the assessment of skin irritancy have been marketed, and have m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16b42f7d1ba0acb6b2489f238174591b
https://doi.org/10.1177/026119299702500306