Výsledky vyhledávání - "L. A. Saint Louis"

Akademický článek

The Brain-Nose Interface: A Potential Cerebrospinal Fluid Clearance Site in Humans

Autor: Neel H. Mehta, Jonah Sherbansky, Angela R. Kamer, Roxana O. Carare, Tracy Butler, Henry Rusinek, Gloria C. Chiang, Yi Li, Sara Strauss, L. A. Saint-Louis, Neil D. Theise, Richard A. Suss, Kaj Blennow, Michael Kaplitt, Mony J. de Leon

Publikováno v: Frontiers in Physiology, Vol 12 (2022)

The human brain functions at the center of a network of systems aimed at providing a structural and immunological layer of protection. The cerebrospinal fluid (CSF) maintains a physiological homeostasis that is of paramount importance to proper neuro

Externí odkaz: https://doaj.org/article/66f26e66bfc045c3b1356ec2725aaaf4

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Longitudinal CSF isoprostane and MRI atrophy in the progression to AD

Autor: Lisa Mosconi, Remigiusz Switalski, S. De Santi, Lidia Glodzik, L. A. Saint Louis, Kenneth Rich, Y. Yao, Domenico Praticò, M. J. de Leon, Wai Hon Tsui, Elizabeth Pirraglia, Miroslaw Brys, Jialin Li, Elizabeth Javier

Publikováno v: Journal of Neurology. 254:1666-1675

Very little data exist to evaluate the value of longitudinal CSF biological markers for Alzheimer's disease (AD). Most studies indicate that tau and amyloid beta markers do not reflect disease progression. We now report on a longitudinal, three-time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771b9d4241d60553f80dd66e2233591f
https://doi.org/10.1007/s00415-007-0610-z

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Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment

Autor: Henry Rusinek, P. Lesbre, John F. DeBernardis, Daniel J. Kerkman, Chaim Tarshish, Peter Davies, W. Tsui, Pankaj Mehta, Susan DeSanti, John T. Poirier, Antonio Convit, Thomas Wisniewski, C. Caraos, Ray Zinkowski, F Qadri, A Gary, S. Segal, M. J. de Leon, L. A. Saint Louis

Publikováno v: Neuroscience Letters. 333:183-186

Cross-sectional cerebrospinal fluid (CSF) levels of tau and amyloid (A) beta (beta) are of diagnostic importance for Alzheimer's disease (AD) and mild cognitive impairment (MCI). However, most longitudinal studies of tau fail to demonstrate progressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7786a41f78192ae3c9ebda0391c110b1
https://doi.org/10.1016/s0304-3940(02)01038-8

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The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease

Autor: Henry Rusinek, Matthew Bobinski, Susan DeSanti, H. M. Wisniewski, Jerzy Wegiel, L. A. Saint Louis, M. J. de Leon, Antonio Convit

Publikováno v: Neuroscience. 95:721-725

For 11 AD cases and four normal elderly controls, post mortem volumes of the hippocampal subdivisions were calculated by using magnetic resonance imaging and histological sections. After at least six weeks of fixation in formalin, brains were examine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758cfeb45dc857bad1cce537f6618958
https://doi.org/10.1016/s0306-4522(99)00476-5

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Asymmetric Progressive Glaucomatous Optic Neuropathy in a Patient With a Rare Developmental Variant of the Ophthalmic Artery

Autor: Zaher Sbeity, Jeffrey M. Liebmann, Syril Dorairaj, L. A. Saint-Louis, Pat Michael Palmiero, Robert Ritch

Publikováno v: Journal of Glaucoma. 17:699-701

PURPOSE To report a case of a developmental anatomic finding of the ophthalmic artery (OA) in a patient with ipsilateral progressive advanced glaucomatous optic neuropathy and visual field loss. METHODS A 59-year-old Asian man with normal tension gla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b600fac39bee6d49e85ab262bce834
https://doi.org/10.1097/ijg.0b013e318168f050

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Contribution of Structural Neuroimaging to the Early Diagnosis of Alzheimer's Disease

Autor: Matthew Bobinski, R. Carroll, L. A. Saint Louis, Henry Rusinek, Ajax E. George, M. J. de Leon, H. M. Wisniewski, Antonio Convit, Susan DeSanti

Publikováno v: International Psychogeriatrics. 9:183-190

There is compelling evidence for the early involvement of the hippocampal formation in the natural history of Alzheimer's disease (AD). The evidence comes from recent neuropathology, neuropsychology, and neuroimaging studies. AD-type histopathologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb338cd8486d3d6d4884646fef957f8
https://doi.org/10.1017/s1041610297004900

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Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease

Autor: Yi Li, Pankaj Mehta, W. Tsui, Ray Zinkowski, Henry Rusinek, Susan DeSanti, M. J. de Leon, Kenneth Rich, Miroslaw Brys, Lisa Mosconi, Juha O. Rinne, L. A. Saint Louis, Kaj Blennow, Domenico Praticò, Lidia Sobanska

Publikováno v: Annals of the New York Academy of Sciences. 1097

It is widely believed that the path to early and effective treatment for Alzheimer's disease (AD) requires the development of early diagnostic markers that are both sensitive and specific. To this aim, using longitudinal study designs, we and others

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790a077c36d3a50eb5007bbfee2c078c
https://pubmed.ncbi.nlm.nih.gov/17413016

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Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment

Publikováno v: Neurobiology of aging. 27(3)

The diagnosis of Alzheimer's disease (AD) in patients with mild cognitive impairment (MCI) is limited because it is based on non-specific behavioral and neuroimaging findings. The lesions of Alzheimer's disease: amyloid beta (Abeta) deposits, tau pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08794f78cf285032bebf499b9b3fc459
https://pubmed.ncbi.nlm.nih.gov/16125823

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