Zobrazeno 1 - 10
of 24
pro vyhledávání: '"L. A. Pohorecky"'
Publikováno v:
Stress. 10:163-172
Stressor activation of the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis can have profound effects on bone and also appetite and metabolism. We tested in rats the response of plasma osteocalcin (pOC, a bone biomarker that is
Publikováno v:
Journal of Studies on Alcohol, Supplement. :180-184
The effect of intruder status in territorial aggression on behavior in the elevated plus-maze, the open field and on 5-HT2 receptor-mediated behaviors was evaluated in male Long-Evans hooded rats. Intruders (350 g) were placed in the home cages of ag
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
The 5-hydroxytryptamine (5-HT)2A receptor is an important component of the neural substrates underlying ethanol (EtOH) intake and behaviors related to anxiety and stress. Paradoxically, both 5-HT2A agonists and antagonists have been shown to reduce E
Publikováno v:
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. 2
One of the prominent symptoms in alcoholics during withdrawal is an intense feeling of anxiety. Recently new tests have become available which may index anxiety in rodents. We have evaluated two such tests in our model of withdrawal from ethanol (ET)
Autor:
L A Pohorecky
Publikováno v:
Journal of Pharmacy and Pharmacology. 38:283-287
The effect of peripherally administered drugs that modify monoaminergic function, on ethanol (2.0 g kg−1, intragastrically)-induced changes in urine output has been examined in rats. The α-noradrenoceptor agonist, clonidine (0.05–0.15 mg kg−1)
Autor:
L. A. Pohorecky
Publikováno v:
Psychopharmacology. 50:125-129
Several behavioral manifestations were evaluated after withdrawal from ethanol in rats maintained for 6 weeks on an all-liquid diet containing ethanol. Compared with control animals (on a sucrose diet) or with animals on the chronic ethanol-containin
Autor:
L A, Pohorecky
Publikováno v:
Advances in experimental medicine and biology.
Publikováno v:
Alcohol and drug research. 6(6)
Development of tolerance to ethanol was examined using heart rate as a measure. Ethanol-treated rats were infused IG with 8-11 g/kg/day (in 3 divided doses), control rats received similar infusions of either equicaloric dextrin-maltose or water (equi
Autor:
D M, Maier, L A, Pohorecky
Publikováno v:
Alcohol and drug research. 6(6)
In male rats given 6.0-8.0 g/kg of ethanol/day via gastric intubation, footshock stress accelerated the development of functional tolerance to ethanol (ethanol-induced hypothermia and motor impairment on a dowel task). A primarily psychological stres
Autor:
L A, Pohorecky, L S, Jaffe
Publikováno v:
Research communications in chemical pathology and pharmacology. 12(3)
These studies were designed to determine several, possibly related, physiological correlates of an acute dose of ethanol. Male rats were injected with 0.5, 1.0, or 2.5 g/kg of ethanol intraperitoneally, and the accumulation of newly synthesized label