Zobrazeno 1 - 10
of 58
pro vyhledávání: '"L. A. Matis"'
Autor:
L. A. Matis, Qile Hu, J. B. Bolen, L. K. T. Gauen, Yuexin Zhu, Andrey S. Shaw, R. D. Klausner, F. Letourneur
Publikováno v:
Molecular and Cellular Biology. 14:3729-3741
The tyrosine-based activation motif is a 20- to 25-amino-acid sequence contained in the cytoplasmic domains of many hematopoietic receptors which is sufficient by itself to reconstitute signalling. This motif is characterized by two YXXL/I sequences
Publikováno v:
The Journal of Experimental Medicine
Immunization of both B10.A and B10.S(9R) mice with pigeon cytochrome c (pcc) elicits T cells capable of proliferating to pcc presented on I-E major histocompatibility complex (MHC) molecules. The T cell receptor (TCR) repertoire used by pcc-specific
Autor:
C. T. Ravirajan, David S. Latchman, Lucienne Papadaki, L. A. Matis, Y. Wang, David A. Isenberg, M Griffiths
Publikováno v:
Rheumatology (Oxford, England). 43(4)
Objectives. There is considerable evidence suggesting that anti-double-stranded deoxyribonucleic acid (anti-dsDNA) antibodies are involved in the pathogenesis of lupus nephritis. It was shown previously using severe combined immune deficient (SCID) m
Autor:
H, Wang, S A, Rollins, Z, Gao, B, Garcia, Z, Zhang, J, Xing, L, Li, R, Kellersmann, L A, Matis, R, Zhong
Publikováno v:
Transplantation. 68(11)
The present study was undertaken to determine whether anti-complement 5 (C5) monoclonal antibodies (mAb) prevent hyperacute rejection (HAR) in a rat-to-presensitized mouse heart transplantation model and whether these mAb, combined with cyclosporine
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(9)
There is controversy regarding the possible role of glial cells as APCs in the pathogenesis of central nervous system (CNS) demyelinating diseases such as multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). Micro
Autor:
L. A. Matis, S. A. Rollins
Publikováno v:
Xenotransplantation ISBN: 9783642644603
The advent of effective strategies to eliminate the hyperacute rejection of porcine organs has placed greater focus on the human anti-porcine cellular interactions that may contribute to discordant xenograft rejection. A better understanding of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17e3264809c25ebc74e88418d30e1f8
https://doi.org/10.1007/978-3-642-60572-7_14
https://doi.org/10.1007/978-3-642-60572-7_14
Autor:
T J, Kroshus, S A, Rollins, A P, Dalmasso, E A, Elliott, L A, Matis, S P, Squinto, R M, Bolman
Publikováno v:
Transplantation. 60(11)
Prevention of hyperacute xenograft rejection in the pig-to-primate combination has been accomplished by removal of natural antibodies, complement depletion with cobra venom factor, or prevention of C3 activation with the soluble complement inhibitor
Publikováno v:
Transplantation. 60(11)
The hyperacute rejection (HAR) of xenotransplanted organs is initiated by the deposition of natural antibodies on donor endothelium followed by the activation of the recipient complement system, which rapidly destroys the graft. Studies of the role o
Publikováno v:
Transplantation. 60(11)
Vascular cell adhesion molecule (VCAM) is expressed on activated endothelial cells and binds to the alpha 4 beta 1 integrin receptor, very late antigen-4 (VLA-4), expressed on human lymphoid cells. Anti-VCAM mAbs have been shown to prolong allograft
Publikováno v:
Transplantation. 57(12)
In this study we present a comprehensive evaluation of the molecular interactions between human T cells and porcine aortic endothelial cells (PAEC) that contribute to human T cell activation. Binding assays demonstrated that porcine erythrocytes (E)