Zobrazeno 1 - 10
of 866
pro vyhledávání: '"L. A. Martins"'
Autor:
Yizhou Yu, Civia Z. Chen, Ivana Celardo, Bryan Wei Zhi Tan, James D. Hurcomb, Nuno Santos Leal, Rebeka Popovic, Samantha H. Y. Loh, L. Miguel Martins
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-16 (2024)
Abstract Alzheimer’s disease (AD) is the most common form of age-related dementia. In AD, the death of neurons in the central nervous system is associated with the accumulation of toxic amyloid β peptide (Aβ) and mitochondrial dysfunction. Mitoch
Externí odkaz:
https://doaj.org/article/605b9850824343b095e198c3f1015e4c
Autor:
Niall A. Buckley, Andrew Craxton, Xiao-Ming Sun, Emanuele Panatta, Lucia Giraldez Pinon, Sina Beier, Lajos Kalmar, Jaime Llodrá, Nobuhiro Morone, Ivano Amelio, Gerry Melino, L. Miguel Martins, Marion MacFarlane
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-13 (2024)
Abstract Dysregulated mitochondrial fusion and fission has been implicated in the pathogenesis of numerous diseases. We have identified a novel function of the p53 family protein TAp73 in regulating mitochondrial dynamics. TAp73 regulates the express
Externí odkaz:
https://doaj.org/article/b7ed34c281d6442daa8f3233d2879a64
Autor:
Emma L. Wilson, Yizhou Yu, Nuno S. Leal, James A. Woodward, Nikolaos Patikas, Jordan L. Morris, Sarah F. Field, William Plumbly, Vincent Paupe, Suvagata R. Chowdhury, Robin Antrobus, Georgina E. Lindop, Yusuf M. Adia, Samantha H. Y. Loh, Julien Prudent, L. Miguel Martins, Emmanouil Metzakopian
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-16 (2024)
Abstract Organelles form membrane contact sites between each other, allowing for the transfer of molecules and signals. Mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) are cellular subdomains characterized by close apposition of mitocho
Externí odkaz:
https://doaj.org/article/2914aeb333b24972878c1604812247ee
Autor:
Isabelle P. A. Magalhaes, Bibiana D. Boger, Nathalia L. Gomes, Guilherme L. P. Martins, Leomarques A. Bomfim, Gustavo F. C. Fagundes, Roberta S. Rocha, Fernando M. A. Coelho, Jose L. Chambo, Ana Claudia Latronico, Maria Candida B. V. Fragoso, Ana O. Hoff, Berenice B. Mendonca, Marcos R. Menezes, Madson Q. Almeida
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
For pheochromocytoma and paraganglioma (PPGL), the efficacy of percutaneous ablative therapies in achieving control of metastatic tumors measuring
Externí odkaz:
https://doaj.org/article/a05ac4f5952e47e791492ce49c6ba160
Autor:
Felix O’Farrell, Benjamin Aleyakpo, Rima Mustafa, Xiyun Jiang, Rui Climaco Pinto, Paul Elliott, Ioanna Tzoulaki, Abbas Dehghan, Samantha H. Y. Loh, Jeff W. Barclay, L. Miguel Martins, Raha Pazoki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Biological pathways between alcohol consumption and alcohol liver disease (ALD) are not fully understood. We selected genes with known effect on (1) alcohol consumption, (2) liver function, and (3) gene expression. Expression of the ortholog
Externí odkaz:
https://doaj.org/article/0325f1b64d454089b354873fd13c3280
Autor:
Charles Cadieux, Mykhaylo Plotnykov, René Doyon, Diana Valencia, Farbod Jahandar, Lisa Dang, Martin Turbet, Thomas J. Fauchez, Ryan Cloutier, Collin Cherubim, Étienne Artigau, Neil J. Cook, Billy Edwards, Tim Hallatt, Benjamin Charnay, François Bouchy, Romain Allart, Lucile Mignon, Frédérique Baron, Susana C. C. Barros, Björn Benneke, B. L. Canto Martins, Nicolas B. Cowan, J. R. De Medeiros, Xavier Delfosse, Elisa Delgado-Mena, Xavier Dumusque, David Ehrenreich, Yolanda G. C. Frensch, J. I. González Hernández, Nathan C. Hara, David Lafrenière, Gaspare Lo Curto, Lison Malo, Claudio Melo, Dany Mounzer, Vera Maria Passeger, Francesco Pepe, Anne-Sophie Poulin-Girard, Nuno C. Santos, Danuta Sosnowska, Alejandro Suárez Mascareño, Simon Thibault, Valentina Vaulato, Gregg A. Wade, François Wildi
Publikováno v:
The Astrophysical Journal Letters, Vol 960, Iss 1, p L3 (2024)
The two-planet transiting system LHS 1140 has been extensively observed since its discovery in 2017, notably with Spitzer, HST, TESS, and ESPRESSO, placing strong constraints on the parameters of the M4.5 host star and its small temperate exoplanets,
Externí odkaz:
https://doaj.org/article/248184ef49024f78bbde20d84a848845
Publikováno v:
Brazilian Journal of Biology, Vol 83 (2023)
Abstract Transgenic Bt soybean plants have been developed to control insect pests, such as Anticarsia gemmatalis and Chrysodeixis includens. This objective has been achieved successfully; however, recently, some authors claimed that Bt soybean plants
Externí odkaz:
https://doaj.org/article/a40edab1c50b4ee78c16674e7ac923ea
Autor:
Rebeka Popovic, Amrita Mukherjee, Nuno Santos Leal, Lydia Morris, Yizhou Yu, Samantha H. Y. Loh, L. Miguel Martins
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-9 (2023)
Abstract Parkinson’s disease (PD) is characterised by selective death of dopaminergic (DA) neurons in the midbrain and motor function impairment. Gastrointestinal issues often precede motor deficits in PD, indicating that the gut-brain axis is invo
Externí odkaz:
https://doaj.org/article/6ebc6adba57e4b589a5e06e303d898c6
Autor:
Armin A. Quispe-Cornejo, Ana L. Alves da Cunha, Hassane Njimi, Wasineenart Mongkolpun, Ana L. Valle-Martins, Mónica Arébalo-López, Jacques Creteur, Jean-Louis Vincent
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-10 (2022)
Abstract Background Rapid fluid administration may decrease hemoglobin concentration (Hb) by a diluting effect, which could limit the increase in oxygen delivery (DO2) expected with a positive response to fluid challenge in critically ill patients. O
Externí odkaz:
https://doaj.org/article/6cf7430100724389a3c5aa6efbac6a2c
Autor:
D. O. Fontinele, P. D. S. de Lima, Y. S. Messias, R. L. Gomes, C. E. Ferreira Lopes, B. L. Canto Martins, I. C. Leão, J. M. De Araújo, E. Janot Pacheco, J. R. De Medeiros
Publikováno v:
The Astrophysical Journal, Vol 973, Iss 2, p 106 (2024)
This study presents the results of a search for rotation signatures in 250 Gaia Data Release 3 ultra-cool dwarfs (UCDs) with TESS light curves (LCs). We identified 71 targets with unambiguous periodicities, of which 61 present rotation signatures and
Externí odkaz:
https://doaj.org/article/f4a00210a01b4ce0aa200f4cc3eb2b20