Zobrazeno 1 - 10
of 48
pro vyhledávání: '"L. A. Malikova"'
Autor:
S. S. Grankin, A. A. Meilekhov, L. V. Malikova, V. A. Stolbovoi, S. V. Litovchenko, V. M. Beresnev, V. Yu. Novikov, Oleg Sobol, S. A. Klimenko, P. V. Turbin
Publikováno v:
Journal of Superhard Materials. 38:114-122
A complex study has been performed of the effect of the technological parameters, which are responsible for the energy states of deposited particles, on the elemental, phase and structure compositions, hardness, and tribological characteristics of fo
Subtilisin-like proteinase secreted by the Bacillus pumilus KMM 62 strain at different growth stages
Autor:
L. A. Malikova, Nelly P. Balaban, Margarita R. Sharipova, N. M. Zamatlyutdinova, Ayslu Mardanova
Publikováno v:
Russian Journal of Bioorganic Chemistry. 38:203-210
Proteinase secreted in the environment by bacilli on different growth stages was isolated by ion chromatography from the culture medium of Bacillus pumilus KMM 62. According to the hydrolysis character of specific chromogenic substrates and inhibitio
Autor:
V. B. Narkevich, Fedotova Ib, P. M. Klodt, K. S. Raevskii, L. A. Malikova, Kudrin Vs, Inga I. Poletaeva
Publikováno v:
Neurochemical Journal. 2:289-292
We have studied the effects of levetiracetam, a novel anticonvulsant drug, on the content of monoamines and their metabolites in the frontal cortex, hypothalamus, striatum, and medulla of rats of the Krushinskii-Molodkina strain using the HPLC techni
Publikováno v:
Microbiology. 76:273-279
The influence of the cultivation conditions on Bacillus pumilus KMM 62 growth and effectiveness of the production of a subtilisin-like serine proteinase were investigated. Enzyme accumulation in the culture fluid reached the maximum value after 32 an
Autor:
Nelly P. Balaban, Galina N. Rudenskaya, Ayslu Mardanova, L A Malikova, Margarita R. Sharipova
Publikováno v:
Biochemistry (Moscow). 72:459-465
Proteinases secreted during the early and late stationary phases have been isolated from the culture liquid of Bacillus amyloliquefaciens H2 using CM-cellulose ion-exchange chromatography with subsequent FPLC on a Mono S column. Considering the chara
Publikováno v:
Bulletin of Experimental Biology and Medicine. 136:7-10
We evaluated the role of nitric oxide and lipid peroxidation in the pathophysiological mechanisms of seizures in genetically epilepsy prone (GEP) rats and DBA/2 mice with genetically determined audiogenic epilepsy. In rats and mice acoustic stimulati
Publikováno v:
Bulletin of Experimental Biology and Medicine. 123:319-322
Bilateral local compression ischemia in the frontal rat brain cortex modifies the levels of neurotransmitter amino acids at the stage of most pronounced disorders in the brain integrative activity. In this model, neuroprotective properties of the dru
Publikováno v:
Bioorganicheskaia khimiia. 38(2)
A protease secreted in Bacillus pumilus KMM 62 culture liquid on different growth stages was isolated using ion-exchange chromatography. On the basis of pattern of specific chromogenic substrates hydrolysis and inhibitory analysis the protease was cl
Autor:
A. V. Volkova, Fedotova Ib, Inga I. Poletaeva, T. S. Kalinina, L. A. Malikova, K. S. Rayevsky, N. M. Surina
Publikováno v:
Bulletin of experimental biology and medicine. 151(1)
We studied plus-maze behavior of inbred Krushinskii−Molodkina, Wistar, and black-hooded rats (originating from the Long-Evans outbred strain) differing by predisposition to audiogenic seizures. The severity of audiogenic seizures partially correlat
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(7)
The novel antiepileptic drug levetiracetam (keppra, 80 mg/kg, i.p.) produces a pronounced anticonvulsant effect on all parameters of the audiogenic locomotion response in Wistar rats, leading to the prevention of acoustic seizures approximately in 50