Výsledky vyhledávání - "L. A. Leksina"

Transition from physiological to pathophysiological indices as exemplified by amyloidosis in periodic disease, non-insulin-dependent diabetes mellitus, and Alzheimer’s disease

Autor: L. A. Piruzyan, L. A. Leksina

Publikováno v: Human Physiology. 35:96-107

Theoretical studies on amyloidosis have been performed. The results promote understanding of primary causes and molecular mechanisms of the formation of pathological protein and permits tracing the transitions from physiological indices to pathologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48e10f452723f28f2e0aa3cbd40fdde9
https://doi.org/10.1134/s0362119709010150

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[A computer study of the relationship between the value and type of their embryotoxicity and the structure of synthetic analogs of biogenic amines]

Autor: I I, Baskin, G A, Buznikov, A S, Kabankin, M A, Landau, L A, Leksina, A A, Ordukhanian, V A, Paliulin, D E, Petelin

Publikováno v: Izvestiia Akademii nauk. Seriia biologicheskaia. (4)

We calculated 219 topological, electronic, and steric indices for each of 59 studied embryotoxic benzylalkylamines and indolamines. Statistically significant equations correlating embryotoxicity and five calculated parameters were obtained using the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ec1acb17d10fc5ca32d9e382e137818
https://pubmed.ncbi.nlm.nih.gov/9410265

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[The computer prognosis of the phenomenon of the superactivity neuropharmacological embryotoxic preparations by using molecular topological parameters and the methods of the sample recognition theory]

Autor: L A, Leksina, A S, Kabankin, A A, Ordukhanian, G A, Buznikov, M A, Landau

Publikováno v: Izvestiia Akademii nauk. Seriia biologicheskaia. (6)

Discriminant functions were obtained on the basis of experimental data on the superactivity of synthetic analogues of the natural biogenic amines (26 active and 33 superactive derivatives of benzene and indole), which allow prognostication of the sup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c5a44b41d937d9a2ef9611b65cf8e65
https://pubmed.ncbi.nlm.nih.gov/8541788

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Change in molecular characteristics during thermal decomposition of cellulose nitrate

Autor: L.P. Smirnov, V.S. Ushakova, L. N. Leksina, Yu.N. Rogov

Publikováno v: Polymer Science U.S.S.R.. 31:387-394

The change in the molecular characteristics of cellulose nitrate as a result of the change in the conditions of thermal decomposition is studied. A decrease of MM and narrowing of the MMD in the flow system are observed, the MM is decreased in the cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b18972b58530b37807cea0c8186092b0
https://doi.org/10.1016/0032-3950(89)90395-x

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Computer analysis of a file of psychotropically active compounds. V. relationship between test results for experimental animals and model enzyme systems

Autor: L. A. Leksina, É. F. Lavretskaya, M. A. Landau, A. S. Kabankin, P. N. Baldenkov

Publikováno v: Pharmaceutical Chemistry Journal. 17:579-581

It was found that the number of tests required to split up the training sample correctly into forms of activity and to give a correct forecast on the activity for new compounds can be reduced considerably: Good results are obtained for certain forms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7eb4d1880fa409d441c8b3d3fcdfcd20
https://doi.org/10.1007/bf00764694

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IR spectra of certain methyl -d-glucopyranoside nitrates

Autor: L. N. Leksina, Nikita V. Chukanov, Sergey I. Firgang, A. I. Usov, Yu.N. Rogov

Publikováno v: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 36:1631-1633

A study has been made of the IR spectra of methyl-β-D-glucopyranoside 2-and 3-nitrates, methyl-α-D-glucopyranoside 6-nitrate, and methyl-4-O-methyl-β-D-glucopyranoside 2,3-and 3,6-dinitrates and 2,3,6-trinitrate.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8050ea14b1fea03a8de21e1dc4d3efa
https://doi.org/10.1007/bf00960119

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