A Clinical Prediction Model to Determine Probability of Response to Certolizumab Pegol for Crohn’s Disease

Autor: Pavine L. C. Lefevre, Parambir S. Dulai, Zhongya Wang, Leonardo Guizzetti, Brian G. Feagan, Anca Pop, Mohamed Yassine, Lisa M. Shackelton, Vipul Jairath, William J. Sandborn, Niels Vande Casteele

Publikováno v: BioDrugs
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, vol 36, iss 1

BackgroundCertolizumab pegol (CZP) is effective for moderately to severely active Crohn's disease (CD). Higher plasma concentrations are associated with better outcomes and increased drug clearance is the driver of subtherapeutic CZP concentrations.O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd70782f66fb7911f482d45aa5854eea
https://europepmc.org/articles/PMC9826742/

260 Impact of BRCA & PD-L1 in EOC patients receiving standard 1st line therapy +/- Pembrolizumab: Exploratory analyses from the NeoPembrOV Study (GINECO)

Autor: L Venat-Bouvet, I.L. Ray-Coquard, L. Bengrine Lefevre, E Coquan, Olfa Derbel, M Martinez, C. Cornila, Marie Ange Mouret-Reynier, T Isabelle, Elsa Kalbacher, O. Le Saux, A.M. Savoye, Olivier Collard, Frank Priou, Dominique Berton, A Angelergues, C Schiffler, Alejandra Martinez, N Cloarec, S Gouerant

Publikováno v: Ovarian cancer.

Introduction/Background* In the randomized phase II NeoPembrOV study (NCT03275506), Pembrolizumab in combination with neoadjuvant chemotherapy (NACT) met its primary endpoint of complete debulking rate (CRR) for the treatment of patients with advance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77cbb85da23e74e9a0c4d330cd2e8abb
https://doi.org/10.1136/ijgc-2021-esgo.369

Successful treatment of meningococcal bacteremia using oral doxycycline: A case report

Autor: Benjamin Davido, Morgan Matt, Latifa Noussair, Aurélien Dinh, S. Simeon, S. Berbescu, L. Armand-Lefevre

Publikováno v: International Journal of Infectious Diseases
International Journal of Infectious Diseases, Elsevier, 2020, 92, pp.78-80. ⟨10.1016/j.ijid.2019.12.032⟩

International audience; We report the case of an 18-year-old immunocompetent man who presented to the hospital with fever, headaches, and arthromyalgia, which progressed to include an erythematous rash. He had a history of a tick bite 72 h earlier. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab99ef9a91087e1f7f547c99c5a07a02
https://doi.org/10.1016/j.ijid.2019.12.032

Perceived burden and quality of life of the primary caregiver of patients aged 70 and over with cancer, 5 years after initial treatment

Autor: V. Quipourt, J. Collot, S. Dabakuyo-Yonli, O. Billa, T. Collot, J. Barben, P. Manckoundia, L. Bengrine Lefevre

Publikováno v: Journal of Geriatric Oncology. 12:S71

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d367832b6d605c7a84966ca5bc1cfc13
https://doi.org/10.1016/s1879-4068(21)00473-2

823P Extended follow-up of a real-world cohort of patients (pts) with BRCA mutation (BRCAm) relapsed epithelial ovarian cancer (EOC) receiving olaparib maintenance therapy: The GINECO RETROLA study

Autor: C. Gavoille, C. Cornila, M-A Mouret-Reynier, D. Coeffic, C. Garnier Tixidre, Dominique Spaeth, Emeline Colomba, Anne Patsouris, Olivier Collard, Michel Fabbro, Camille Chakiba, B. Lucas, D. Garbay, P. Toussaint, H. Simon, Dominique Berton, C. Lefeuvre-Plesse, T. de La Motte Rouge, Bernard Asselain, L. Bengrine Lefevre

Publikováno v: Annals of Oncology. 31:S621-S622

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::34612ab25cb728a3a0cfb24584951304
https://doi.org/10.1016/j.annonc.2020.08.962