Zobrazeno 1 - 10
of 28
pro vyhledávání: '"L. A. Conroy"'
Autor:
Dominic J. Corkill, F Koentgen, E C Martin, J Powell, L A Conroy, Nicola H.E. Davis, Joanne Woods, E. S. Cohen, Phillip Monk, N Brennan, Alison J. Dodd, R. M. Wilson, D Manuel, C Joberty-Candotti, F Dempsey, I.K. Anderson, Richard D. May
Publikováno v:
British Journal of Pharmacology. 166:177-193
BACKGROUND AND PURPOSE IL-13 is a pleiotropic Th2 cytokine considered likely to play a pivotal role in asthma. Here we describe the preclinical in vitro and in vivo characterization of CAT-354, an IL-13-neutralizing IgG4 monoclonal antibody (mAb), cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d66ac00a4592a4a548a0f9e1bf51ec
https://doi.org/10.1111/j.1476-5381.2011.01659.x
https://doi.org/10.1111/j.1476-5381.2011.01659.x
Autor:
Erica L. Campbell-Conroy, Dennis James Hurley, Jinglan Zhou, Alina Silina, Uy Johnny, Michael Paul Deninno, Bryan A. Frieman, Pierre Fabrice Jean Denis, Nicole Hilgraf
Publikováno v:
The Journal of organic chemistry. 80(1)
An array of six pyridyl-substituted fused bicyclic piperidines was prepared as novel cores for medicinal chemistry. For maximum diversity, the size of the fused ring varied from three to six atoms and contained up to two oxygen atoms. The pyridine ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e80eb3ce510545db78ec4f3d4156cd
https://pubmed.ncbi.nlm.nih.gov/25405702
https://pubmed.ncbi.nlm.nih.gov/25405702
Publikováno v:
The Journal of Immunology. 158:5773-5782
CD45 is a transmembrane phosphotyrosine phosphatase expressed on all nucleated hemopoietic cells. Targeting of CD45 exon 9 has generated a mouse line completely lacking CD45 expression (CD45-null) in which there are severe abnormalities in T cell dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c03a8bd6648317d5915ab66daa561d5
https://doi.org/10.4049/jimmunol.158.12.5773
https://doi.org/10.4049/jimmunol.158.12.5773
Autor:
R D, May, P D, Monk, E S, Cohen, D, Manuel, F, Dempsey, N H E, Davis, A J, Dodd, D J, Corkill, J, Woods, C, Joberty-Candotti, L A, Conroy, F, Koentgen, E C, Martin, R, Wilson, N, Brennan, J, Powell, I K, Anderson
Publikováno v:
British Journal of Pharmacology
BACKGROUND AND PURPOSE IL-13 is a pleiotropic Th2 cytokine considered likely to play a pivotal role in asthma. Here we describe the preclinical in vitro and in vivo characterization of CAT-354, an IL-13-neutralizing IgG4 monoclonal antibody (mAb), cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5de2d16c0e4841a1ce276ca0dd0e33e6
https://pubmed.ncbi.nlm.nih.gov/21895629
https://pubmed.ncbi.nlm.nih.gov/21895629
Autor:
L. E. Conroy
Publikováno v:
Inorganic Reactions and Methods: Formation of Bonds to O, S, Se, Te, Po (Part 2), Volume 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f893861438eb2eb46ce5898dfba74cb8
https://doi.org/10.1002/9780470145203.ch154
https://doi.org/10.1002/9780470145203.ch154
Autor:
L. E. Conroy
Publikováno v:
Inorganic Reactions and Methods: Formation of Bonds to O, S, Se, Te, Po (Part 2), Volume 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::352362d0007f71902a202b00cff10f0f
https://doi.org/10.1002/9780470145203.ch153
https://doi.org/10.1002/9780470145203.ch153
Autor:
L. E. Conroy
Publikováno v:
Inorganic Reactions and Methods: Formation of Bonds to O, S, Se, Te, Po (Part 2), Volume 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce8721561449de775ce66b033b34c10
https://doi.org/10.1002/9780470145203.ch111
https://doi.org/10.1002/9780470145203.ch111
Publikováno v:
The Annals of occupational hygiene. 44(6)
The objective of this research was to compare mathematical models of the fluid velocity in the vicinity of an open tank with lateral slot exhaust. Two approaches were explored: a numerical solution assuming turbulent flow and an analytical solution a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f93dc6be5e51ad0bbd46e7eec848a3c2
https://pubmed.ncbi.nlm.nih.gov/10963705
https://pubmed.ncbi.nlm.nih.gov/10963705
Autor:
L. A. Conroy, J. D. Stone, Nick Holmes, J. A. Frearson, K. F. Byth, Sarah Howlett, Denis R. Alexander
Publikováno v:
Biochemical Society transactions. 25(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91558582d3c276945f6c968efdcb6024
https://pubmed.ncbi.nlm.nih.gov/9191133
https://pubmed.ncbi.nlm.nih.gov/9191133
Autor:
L A, Conroy, D R, Alexander
Publikováno v:
Leukemia. 10(9)
Apoptosis plays a critical role during T cell development, both in the generation of functionally competent T cells in the thymus and the regulation of peripheral T cell populations. The fate of any T cell, whether it is developing in the thymus, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fbde7e2dc30b25ee744966652a57ee4
https://pubmed.ncbi.nlm.nih.gov/8751458
https://pubmed.ncbi.nlm.nih.gov/8751458