Zobrazeno 1 - 10
of 109
pro vyhledávání: '"L. A. Bowers"'
Autor:
Kelly M. Grimes, Vikram Prasad, Jiuzhou Huo, Yasuhide Kuwabara, Davy Vanhoutte, Tanya A. Baldwin, Stephanie L. K. Bowers, Anne Katrine Z. Johansen, Michelle A. Sargent, Suh-Chin J. Lin, Jeffery D. Molkentin
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: The ribosomal protein L3-like (RPL3L) is a heart and skeletal muscle-specific ribosomal protein and paralogue of the more ubiquitously expressed RPL3 protein. Mutations in the human RPL3L gene are linked to childhood cardiomyopathy and
Externí odkaz:
https://doaj.org/article/e9e91a84e9de42468035dd74dbc281e1
Autor:
Stephanie L. K. Bowers, Qinghang Meng, Yasuhide Kuwabara, Jiuzhou Huo, Rachel Minerath, Allen J. York, Michelle A. Sargent, Vikram Prasad, Anthony J. Saviola, David Ceja Galindo, Kirk C. Hansen, Ronald J. Vagnozzi, Katherine E. Yutzey, Jeffery D. Molkentin
Publikováno v:
Cells, Vol 12, Iss 17, p 2174 (2023)
Rationale: The adult cardiac extracellular matrix (ECM) is largely comprised of type I collagen. In addition to serving as the primary structural support component of the cardiac ECM, type I collagen also provides an organizational platform for other
Externí odkaz:
https://doaj.org/article/bc1cebba95e0499bb087b9d6cd86552f
Publikováno v:
Nature Cardiovascular Research. 1:312-321
Autor:
Dae Joong Kim, Pieter R Norden, Jocelynda Salvador, David M Barry, Stephanie L K Bowers, Ondine Cleaver, George E Davis
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184461 (2017)
Here we examine the question of how endothelial cells (ECs) develop their apical membrane surface domain during lumen and tube formation. We demonstrate marked apical membrane targeting of activated Src kinases to this apical domain during early and
Externí odkaz:
https://doaj.org/article/f1a989f8e0584da284439abdd48c2c64
Cardiac fibroblasts regulate cardiomyocyte hypertrophy through dynamic regulation of type I collagen
Autor:
Qinghang Meng, Stephanie L. K. Bowers, Yasuhide Kuwabara, Jiuzhou Huo, Rachel Minerath, Allen J. York, Michelle A. Sargent, Vikram Prasad, Anthony J. Saviola, David Ceja Galindo, Kirk C. Hansen, Ronald J. Vagnozzi, Katherine E. Yutzey, Jeffery D. Molkentin
RationaleCardiomyocytes and fibroblasts in the heart communicate through both secreted growth factors as well as through sensing the structural properties of the extracellular matrix that each helps generate. Previous studies have shown that defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f27790df13357df1234b902ad0d4ec8f
https://doi.org/10.1101/2022.05.25.493406
https://doi.org/10.1101/2022.05.25.493406
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85147 (2013)
We describe a novel 3D fibrin matrix model using recombinant hematopoietic stem cell cytokines under serum-free defined conditions which promotes the assembly of human endothelial cell (EC) tubes with co-associated pericytes. Individual ECs and peric
Externí odkaz:
https://doaj.org/article/270db60ce53347f49d8813b64634a364
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e49704 (2012)
Concern for a pandemic caused by a newly emerged avian influenza A virus has led to clinical trials with candidate vaccines as preparation for such an event. Most trials have involved vaccines for influenza A (H5N1), A (H7N7) or A (H9N2).To evaluate
Externí odkaz:
https://doaj.org/article/46b6c432cc9340afa7d1ed84537fd8b4
Autor:
Davis-Rodriguez Stephanie R, Zachary M. Thomas, Prasad Devarajan, Valeria Rudomanova, W. Clark Bacon, Stephanie L. K. Bowers, Burns C. Blaxall, Alex Beiersdorfer, Qing Ma
Publikováno v:
Am J Physiol Renal Physiol
Fibrosis is a common feature of chronic kidney disease; however, no clinical therapies effectively target the progression of fibrosis. Inhibition of fibronectin polymerization with the small peptide pUR4 attenuates fibrosis in the liver and heart. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba5d76f1c693c50b7ba8af8a7e097ee
https://europepmc.org/articles/PMC6620592/
https://europepmc.org/articles/PMC6620592/
Autor:
A. B. Stefaniak, L. N. Bowers, A. K. Knepp, T. P. Luxton, D. M. Peloquin, E. J. Baumann, J. E. Ham, J. R. Wells, A. R. Johnson, R. F. LeBouf, F.-C. Su, S. B. Martin, M. A. Virji
Little is known about emissions and exposure potential from vat polymerization additive manufacturing, a process that uses light-activated polymerization of a resin to build an object. Five vat polymerization printers (three stereolithography (SLA) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179bee29dc79c8cb445a2f3f59f752ac
Publikováno v:
Connective Tissue Research. 56:392-402
This review addresses fundamental mechanisms underlying how capillaries form in three-dimensional extracellular matrices and how endothelial cells (ECs) and pericytes co-assemble to form capillary networks. In addition to playing a critical role in s