Zobrazeno 1 - 10
of 77
pro vyhledávání: '"L. A. Aarden"'
Autor:
J.C. van Denderen, Mike J L Peters, Gertjan Wolbink, L. A. Aarden, Ben A. C. Dijkmans, M.K. de Vries, Michael T. Nurmohamed, S.O. Stapel, I E van der Horst-Bruinsma
Publikováno v:
Annals of the rheumatic diseases, 68(4), 531-535. BMJ Publishing Group
de Vries, M K, van der Horst-Bruinsma, I E, Nurmohamed, M T, Aarden, L, Stapel, S N, Peters, M J L, van Denderen, A C, Dijkmans, B A C & Wolbink, G 2009, ' Immunogenicity does not influence treatment with etanercept in patients with ankylosing spondylitis ', Annals of the Rheumatic Diseases, vol. 68, no. 4, pp. 531-535 . https://doi.org/10.1136/ard.2008.089979
Annals of the Rheumatic Diseases, 68(4), 531-535. BMJ Publishing Group
de Vries, M K, van der Horst-Bruinsma, I E, Nurmohamed, M T, Aarden, L, Stapel, S N, Peters, M J L, van Denderen, A C, Dijkmans, B A C & Wolbink, G 2009, ' Immunogenicity does not influence treatment with etanercept in patients with ankylosing spondylitis ', Annals of the Rheumatic Diseases, vol. 68, no. 4, pp. 531-535 . https://doi.org/10.1136/ard.2008.089979
Annals of the Rheumatic Diseases, 68(4), 531-535. BMJ Publishing Group
Background:Immunogenicity, specifically the onset of antibodies against tumour necrosis factor (TNF) blocking agents, seems to play an important role in non-response to treatment with these drugs.Objectives:To assess the relation of clinical response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ff130e82aa3c95a599190b27b814ab
https://doi.org/10.1136/ard.2008.089979
https://doi.org/10.1136/ard.2008.089979
Publikováno v:
Oral microbiology and immunology, 22(3), 145-151. Wiley-Blackwell
Oral Microbiology and Immunology, 22(3), 145-151. Wiley-Blackwell
Kikkert, R, Laine, M L, Aarden, L A & van Winkelhoff, A J 2007, ' Activiation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria ', Oral Microbiology and Immunology, vol. 22, no. 3, pp. 145-151 . https://doi.org/10.1111/j.1399-302X.2007.00335.x
Oral Microbiology and Immunology, 22(3), 145-151. Wiley-Blackwell
Kikkert, R, Laine, M L, Aarden, L A & van Winkelhoff, A J 2007, ' Activiation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria ', Oral Microbiology and Immunology, vol. 22, no. 3, pp. 145-151 . https://doi.org/10.1111/j.1399-302X.2007.00335.x
Background/aims: Periodontitis is a chronic infectious disease associated with a gram-negative subgingival microflora. Bacterial components stimulate, among other receptors, Toll-like receptor (TLR) 2 and/or TLR4. Accumulating evidence indicates that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0baa40183d535b16bd481687bd966867
https://doi.org/10.1111/j.1399-302x.2007.00335.x
https://doi.org/10.1111/j.1399-302x.2007.00335.x
Autor:
R J van de Stadt, I E van der Horst-Bruinsma, M M J Nielen, A R van der Horst, Dörte Hamann, L. A. Aarden, D. van Schaardenburg, B A C Dijkmans
Publikováno v:
Annals of the rheumatic diseases, 64(8), 1199-1204. BMJ Publishing Group
Annals of the Rheumatic Diseases, 64(8), 1199-1204. BMJ Publishing Group
Nielen, MM, van der Horst, A R, van Schaardenburg, D, van der Horst-Bruinsma, I E, van de Stadt, RJ, Aarden, L A, Dijkmans, B A C & Hamann, D 2005, ' Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis ', Annals of the Rheumatic Diseases, vol. 64, no. 8, pp. 1199-1204 . https://doi.org/10.1136/ard.2004.029389
Annals of the Rheumatic Diseases, 64(8), 1199-1204. BMJ Publishing Group
Nielen, MM, van der Horst, A R, van Schaardenburg, D, van der Horst-Bruinsma, I E, van de Stadt, RJ, Aarden, L A, Dijkmans, B A C & Hamann, D 2005, ' Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis ', Annals of the Rheumatic Diseases, vol. 64, no. 8, pp. 1199-1204 . https://doi.org/10.1136/ard.2004.029389
Background: The anti-cyclic citrullinated peptide (CCP) test has a high sensitivity and specificity for rheumatoid arthritis, although CCP is not the physiological target of the autoantibodies. Citrullinated fibrin is abundant in inflamed synovium Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdf3639b6f07c1ae9b03e9581fac3a9
https://hdl.handle.net/1871/23200
https://hdl.handle.net/1871/23200
Publikováno v:
Blood. 87:5051-5060
Acute inflammatory illnesses, including the sepsis syndrome, often include a component of coagulation. A human whole blood culture system was developed so that the relationship between coagulation activation and cytokine responses in the presence or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fa65d674fbbc1c28f2701a77af9f9b8
https://doi.org/10.1182/blood.v87.12.5051.bloodjournal87125051
https://doi.org/10.1182/blood.v87.12.5051.bloodjournal87125051
Publikováno v:
The Journal of Immunology. 156:1818-1823
IL-13, a T cell-derived cytokine, shares many of its biologic activities with the Th2 cytokine IL-4, including induction of a class switch to IgE and anti-inflammatory properties. Its potential impact on development of Th2 responses makes it interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19564fa2da80a0ca7703738540a11975
https://doi.org/10.4049/jimmunol.156.5.1818
https://doi.org/10.4049/jimmunol.156.5.1818
Publikováno v:
Clinical and Experimental Immunology. 99:473-478
SUMMARY In lymphocyte cultures, IgE production was achieved by stimulating T cells with anti-CD2 and IL-2. Here we show that anti-CD28, in the presence or absence of IL-2, reduces this IgE production approximately 10-fold. This inhibition of IgE prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa78d0110df16555a56c2d0ce5adf3e
https://doi.org/10.1111/j.1365-2249.1995.tb05575.x
https://doi.org/10.1111/j.1365-2249.1995.tb05575.x
Publikováno v:
Clinical and experimental immunology, 97(2), 254-259. Wiley-Blackwell
SUMMARYTo analyse whether there is a general defect in T or B cell function in atopic individuals we have measured cytokine and IgE production by peripheral blood lymphocytes, isolated from 19 atopic donors (17 asthma/rhinitis and two dermatitis pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99a0da1d829aa90b64b25e3c3865ebe
https://doi.org/10.1111/j.1365-2249.1994.tb06077.x
https://doi.org/10.1111/j.1365-2249.1994.tb06077.x
Autor:
P. J. Den Boer, J. C. Bakker, E. M. De Groot, Wim K. Bleeker, P. T. M. Biessels, L. A. Aarden
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 22:835-840
Induction of interleukin-6 (IL-6) production by isolated human mononuclear blood cells was taken as in vitro model for the induction of inflammatory reactions. The model was very sensitive to bacterial endotoxin (detection limit < 10pg/ml). Hemoglobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc82ecb45f17d840bc51708c5b643d98
https://doi.org/10.3109/10731199409117918
https://doi.org/10.3109/10731199409117918
Autor:
Anna Jamnitski, Michael T. Nurmohamed, B A C Dijkmans, A E Voskuyl, M. Hart, L. A. Aarden, C. Krieckaert, G.J. Wolbink
Publikováno v:
Annals of the Rheumatic Diseases, 71(1), 88-91. BMJ Publishing Group
Jamnitski, A, Krieckaert, C L, Nurmohamed, M T, Hart, M H, Dijkmans, B A C, Aarden, L, Voskuyl, A E & Wolbink, G J 2012, ' Patients non-responding to etanercept obtain lower etanercept concentrations compared with responding patients ', Annals of the Rheumatic Diseases, vol. 71, no. 1, pp. 88-91 . https://doi.org/10.1136/annrheumdis-2011-200184
Jamnitski, A, Krieckaert, C L, Nurmohamed, M T, Hart, M H, Dijkmans, B A C, Aarden, L, Voskuyl, A E & Wolbink, G J 2012, ' Patients non-responding to etanercept obtain lower etanercept concentrations compared with responding patients ', Annals of the Rheumatic Diseases, vol. 71, no. 1, pp. 88-91 . https://doi.org/10.1136/annrheumdis-2011-200184
ObjectiveTo investigate the relationship between serum etanercept levels and clinical response.MethodsIn 292 etanercept-treated patients with rheumatoid arthritis clinical and pharmacological data were determined at baseline and after 1, 4 and 6 mont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a490daf6bfb4097d703e0e9722e882
https://pubmed.ncbi.nlm.nih.gov/21914626
https://pubmed.ncbi.nlm.nih.gov/21914626
Autor:
Onno Teng, Koen Vos, J.M. van Laar, Gertjan Wolbink, Danielle M. Gerlag, S.O. Stapel, Paul P. Tak, Rogier M. Thurlings, L. A. Aarden
Publikováno v:
Annals of the Rheumatic Diseases, 69(2), 409-412. BMJ Publishing Group
Annals of the Rheumatic Diseases, 69(2), 409-412
Annals of the rheumatic diseases, 69(2), 409-412. BMJ Publishing Group
Annals of the Rheumatic Diseases, 69(2), 409-412
Annals of the rheumatic diseases, 69(2), 409-412. BMJ Publishing Group
Objectives:To analyse whether persistence of synovial B lineage cells and lack of clinical response to rituximab treatment in patients with rheumatoid arthritis (RA) are associated with low rituximab serum levels and anti-rituximab antibody (ARA) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d93f2a979293f2e7b6c6364303231d
https://doi.org/10.1136/ard.2009.109041
https://doi.org/10.1136/ard.2009.109041
