Zobrazeno 1 - 10
of 377
pro vyhledávání: '"L. Gaffo"'
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Objective To determine if methotrexate or folic acid prescription was associated with differential risk for COVID-19 diagnosis or mortality.Design Case–control analysis.Setting The population-based UK Biobank (UKBB) cohort.Participants Data from 38
Externí odkaz:
https://doaj.org/article/a8ff62656ebe47a3a970fbc563fe0ef0
Autor:
Huai Leng Pisaniello, Mark C. Fisher, Hamish Farquhar, Ana Beatriz Vargas-Santos, Catherine L. Hill, Lisa K. Stamp, Angelo L. Gaffo
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-18 (2021)
Abstract Gout flare prophylaxis and therapy use in people with underlying chronic kidney disease (CKD) is challenging, given limited treatment options and risk of worsening renal function with inappropriate treatment dosing. This literature review ai
Externí odkaz:
https://doaj.org/article/a9b2cd32111d4965b307ccb47208a308
Autor:
Mariana Urquiaga, Angelo L. Gaffo
Publikováno v:
Gout, Urate, and Crystal Deposition Disease. 1:37-48
Gout is a prevalent and burdensome condition despite the advances in our knowledge of its underlying mechanisms, prevention, and treatment. There is still work to be done to elucidate relevant questions that could lead to better patient care. This co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998bd652787158c558d5d2e0b62e3517
https://doi.org/10.3390/gucdd1010005
https://doi.org/10.3390/gucdd1010005
Autor:
Mengying Sun, Ana I. Vazquez, Richard J. Reynolds, Jasvinder A. Singh, Mathew Reeves, Tony R. Merriman, Angelo L. Gaffo, Gustavo de los Campos
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-9 (2018)
Abstract Background Many gout comorbidities (e.g., hypertension) are correlated with serum urate. In this investigation, we identified risk factors (e.g., systolic blood pressure [SBP]), that (1) are associated with incident gout, (2) have effects on
Externí odkaz:
https://doaj.org/article/7458e45350db42b4ae846fa635980991
Autor:
Joshua Melnick, Amy S. Mudano, Angelo L. Gaffo, Nicola Dalbeth, Jeffrey Foster, Anthony Doyle, Stephanie R. Biggers-Clark, Anne Horne, David T. Redden, Kenneth G. Saag
Publikováno v:
Seminars in Arthritis and Rheumatism. 51:1218-1223
Background/Purpose Disordered osteoclast activity has been implicated in the pathogenesis of gouty bone erosion. We sought to determine if the addition of denosumab (a monoclonal antibody targeting the receptor activator of nuclear factor kappa-B lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d066af1f1d461eaa0568db4fd21808
https://doi.org/10.1016/j.semarthrit.2021.10.002
https://doi.org/10.1016/j.semarthrit.2021.10.002
Autor:
Nagisa Morikawa, Yuichiro Yano, Angelo L. Gaffo, Myron D. Gross, David R. Jacobs, Daniel Duprez, Masanari Kuwabara, Michael P. Bancks
Publikováno v:
Hypertension
Serum urate levels have been shown to be correlated with risk for incident cardiovascular disease (CVD) events among middle-aged or older adults. However, serum urate trajectory during young adulthood and its association with CVD events has been unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae78e938d2e809340c22f0b1a0e4fb3
https://doi.org/10.1161/hypertensionaha.121.17555
https://doi.org/10.1161/hypertensionaha.121.17555
Publikováno v:
BMC Rheumatology, Vol 5, Iss 1, Pp 1-7 (2021)
BMC Rheumatology
BMC Rheumatology
Background Previous studies have noted significant variation in serum urate (sUA) levels, and it is unknown how this influences the accuracy of hyperuricemia classification based on single data points. Despite this known variability, hyperuricemic pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf72a038205bf014927bb4d96618e7c6
https://doaj.org/article/f8902957171d435792fac8a4ebf17807
https://doaj.org/article/f8902957171d435792fac8a4ebf17807
Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities
Autor:
Robert Terkeltaub, Lisa K. Stamp, David B. Mount, Huai Leng Pisaniello, Angelo L. Gaffo, Mark Fisher, Hyon K. Choi, Ana Beatriz Vargas-Santos, Hamish Farquhar, Christopher Hill
Publikováno v:
Nature Reviews. Rheumatology
Gout and chronic kidney disease (CKD) frequently coexist, but quality evidence to guide gout management in people with CKD is lacking. Use of urate-lowering therapy (ULT) in the context of advanced CKD varies greatly, and professional bodies have iss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a456b5a13abda110c9a88c1265f5747
https://doi.org/10.1038/s41584-021-00657-4
https://doi.org/10.1038/s41584-021-00657-4
Autor:
Kenneth G. Saag, Leslie Lang, Elsayed Z. Soliman, S. Louis Bridges, Tony R. Merriman, Ninad S. Chaudhary, George Howard, Lisandro D. Colantonio, Monika M. Safford, Richard J. Reynolds, Timothy B Plante, Nicole D. Armstrong, Paul Muntner, Angelo L. Gaffo, Marguerite R. Irvin, Jeffrey R. Curtis, Jasvinder A. Singh
Publikováno v:
J Rheumatol
Objective.To determine the association of serum urate (SU) levels with sudden cardiac death and incident coronary heart disease (CHD), separately, among adults without a history of CHD.Methods.We conducted a case-cohort analysis of Black and White pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6599407f7829724785daab5c4977dbf
https://doi.org/10.3899/jrheum.210139
https://doi.org/10.3899/jrheum.210139
Autor:
Sebastian E. Sattui, Angelo L. Gaffo, David A. Calhoun, Phillip J. Foster, Suzanne Oparil, Peng Li, Tanja Dudenbostel, Paul Muntner, S. Louis Bridges, Michael B. Saddekni, Daniel I. Feig, David T. Redden, Stephanie R. Biggers-Clark, Amy S. Mudano, Elizabeth J. Rahn, Kenneth G. Saag
Publikováno v:
Arthritis & Rheumatology. 73:1514-1522
OBJECTIVE To determine whether serum urate reduction with allopurinol lowers blood pressure (BP) in young adults and the mechanisms mediating this hypothesized effect. METHODS We conducted a single-center, randomized, double-blind, crossover clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29707bcfed49a99a8b1c1eeccb99a000
https://doi.org/10.1002/art.41749
https://doi.org/10.1002/art.41749