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pro vyhledávání: '"L-M Ching"'
Akademický článek
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Autor:
K Guo, L-M Ching, L-C S Wang, Kimiora Henare, Sofian M. Tijono, Brian D. Palmer, Steven M. Albelda
Publikováno v:
British Journal of Cancer
Background: Species selectivity of DMXAA (5,6-dimethylxanthenone-4-acetic acid, Vadimezan) for murine cells over human cells could explain in part the recent disappointing phase III trials clinical results when preclinical studies were so promising.
Publikováno v:
Cancer Genetics and Cytogenetics. 118:24-27
We describe a case of T-lymphoblastic lymphoma (T-LBL) in a 13-year-old boy in which conventional cytogenetic analysis of lymph node tissue showed complex karyotypic aberrations including add(1p), add(2q), and multiple chromosomal deletions involving
Akademický článek
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Publikováno v:
Cancer Genetics and Cytogenetics. 93:172-176
Three consecutive cases of pediatric myelodysplastic syndrome (MDS) diagnosed over a three-year period in Queen Mary Hospital, Hong Kong, were described. Depending on the classification system used, they comprised two cases of chronic myelomonocytic
Autor:
Tong Zhang, Long Jun Gu, Shao Qin Kuang, Wei Huang, Sai Juan Chen, Zhu Chen, Shuo Dong, L. M. Ching, Qiu Hua Huang, L. C. Chang
Publikováno v:
Cancer Genetics and Cytogenetics. 81:76-82
The TAL-1 gene is located on chromosome 1p32. In about 20% of T-cell acute lymphoblastic leukemias (T-ALL), this gene is disrupted in its 5' portion by a site-specific 100-kg deletion and is fused with the 5' part of the SIL gene, to form SIL-TAL-1 c
Publikováno v:
The Journal of Immunology. 153:4684-4693
The synthetic flavone analogue 5,6-dimethylxanthenone-4-acetic acid (5,6-MeXAA) has shown promise as an antitumor agent and is currently a candidate for clinical trials. Because 5,6-MeXAA has been shown in a murine macrophage and a human myelomonocyt
Publikováno v:
American Journal of Hematology. 43:211-215
The translocation (8;21)(q22;q22) is commonly associated with acute myeloid leukemia (AML) M2 according to the French-American-British (FAB) classification. We describe 11 cases of t(8;21) diagnosed by strict FAB criteria. Six cases were diagnosed as
Publikováno v:
Cancer Genetics and Cytogenetics. 62:154-159
The karyotypes of 98 patients between the ages of 8 and 81 years with acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and chronic myeloid leukemia (CML) are presented. Although the well-described cyt
Publikováno v:
Cancer research. 61(5)
The promise of cancer immunotherapy is that it will not only eradicate primary tumors but will generate systemic antitumor immunity capable of destroying distant metastases. A major problem that must first be surmounted relates to the immune resistan